Zobrazeno 1 - 10
of 62
pro vyhledávání: '"ubash3a"'
Autor:
Jie Wang, Chunlin Wang, Anling Hu, Kunlin Yu, Yi Kuang, Babu Gajendran, Eldad Zacksenhaus, Klarke Michael Sample, Xiao Xiao, Wuling Liu, Yaacov Ben-David
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background FLI1 is an oncogenic transcription factor that promotes diverse malignancies through mechanisms that are not fully understood. Herein, FLI1 is shown to regulate the expression of Ubiquitin Associated and SH3 Domain Containing A/B
Externí odkaz:
https://doaj.org/article/1e7a10e00166424bb547a8f8b2b0ef0d
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1932 (2024)
UBASH3A and UBASH3B are protein families of atypical protein tyrosine phosphatases that function as regulators of various cellular processes during mammalian development. As UBASH3A has only mild phosphatase activity, its regulatory effects are based
Externí odkaz:
https://doaj.org/article/5e61ae5c160a49b18fc5aa8095811b90
Autor:
Kaoru Yamagata, Shingo Nakayamada, Tong Zhang, Anh Phuong Nguyen, Naoyuki Ohkubo, Shigeru Iwata, Shigeaki Kato, Yoshiya Tanaka
Publikováno v:
Inflammation and Regeneration, Vol 42, Iss 1, Pp 1-14 (2022)
Abstract Background Rheumatoid arthritis (RA) is associated with immune dysfunction. UBASH3A as a negative regulator of T cell receptors (TCRs) signaling is a susceptible factor in RA. The aim of this study was to determine the role of UBASH3A in RA
Externí odkaz:
https://doaj.org/article/d80214a85f0b444d934e00ead7d3fba4
Akademický článek
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Autor:
Alexander Y. Tsygankov
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9126 (2023)
The two members of the UBASH3/STS/TULA protein family have been shown to critically regulate key biological functions, including immunity and hemostasis, in mammalian biological systems. Negative regulation of signaling through immune receptor tyrosi
Externí odkaz:
https://doaj.org/article/2b115646c93e45e6946bfbc213275742
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8671 (2023)
UBASH3A is a negative regulator of T cell activation and IL-2 production and plays key roles in autoimmunity. Although previous studies revealed the individual effects of UBASH3A on risk for type 1 diabetes (T1D; a common autoimmune disease), the rel
Externí odkaz:
https://doaj.org/article/7bfdea4e54db416b9b09e114bf8eb162
Akademický článek
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Autor:
Xiao-Ke Yang, Juan Liu, Shan-Yu Chen, Mu Li, Ming-Ming Zhang, Rui-Xue Leng, Hai-Feng Pan, Yuan Shen, Wen-Xue Liu, Sheng-Qian Xu, Dong-Qing Ye, Zong-Wen Shuai
Publikováno v:
Autoimmunity, Vol 52, Iss 1, Pp 21-26 (2019)
Objectives: Recent evidence has demonstrated that UBASH3A play a pivotal role in multiple autoimmune diseases. In this study, we explored the association between UBASH3A gene single-nucleotide polymorphisms (SNPs) and rheumatoid arthritis (RA) in a C
Externí odkaz:
https://doaj.org/article/5afc92776b574a86987c96b6dc128f5c
Autor:
Mirela Lozic, Luka Minarik, Anita Racetin, Natalija Filipovic, Mirna Saraga Babic, Katarina Vukojevic
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9183 (2021)
We aimed to investigate the spatio-temporal expression of possible CAKUT candidate genes CRKL, AIFM3, and UBASH3A, as well as AIF and BCL2 during human kidney development. Human fetal kidney tissue was stained with antibodies and analyzed by fluoresc
Externí odkaz:
https://doaj.org/article/fff30a7a3c6a4205b88a6e2043d48810
Akademický článek
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