Zobrazeno 1 - 10
of 23
pro vyhledávání: '"uPA, urokinase type plasminogen activator"'
Autor:
Andrew W. Duncan, Yong-Kook Kwon, Arman Zarnegar, Xinping Tan, Marie C. DeFrances, Evan R. Delgado, Jihong Ma, Reza Zarnegar
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 2, Pp 565-582 (2022)
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 2, Pp 565-582 (2022)
Background & Aims Nonalcoholic fatty liver disease is a frequent cause of hepatic dysfunction and is now a global epidemic. This ailment can progress to an advanced form called nonalcoholic steatohepatitis (NASH) and end-stage liver disease. Currentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30958d41e6dcdb7086f377f001ad86cf
https://pubmed.ncbi.nlm.nih.gov/34756982
https://pubmed.ncbi.nlm.nih.gov/34756982
Autor:
Fuentes-Prior, Pablo
Publikováno v:
The Journal of Biological Chemistry
Journal of Biological Chemistry
Journal of Biological Chemistry
The ongoing COVID-19 pandemic has already caused over a million deaths worldwide, and this death toll will be much higher before effective treatments and vaccines are available. The causative agent of the disease, the coronavirus SARS-CoV-2, shows im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a890ea4d258fb6275e96e74e6acce01
https://doi.org/10.1074/jbc.rev120.015980
https://doi.org/10.1074/jbc.rev120.015980
Publikováno v:
The Journal of Biological Chemistry
Advances in cancer biology are revealing the importance of the cancer cell microenvironment on tumorigenesis and cancer progression. Hyaluronan (HA), the main glycosaminoglycan in the extracellular matrix, has been associated with the progression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e51a668982b77746ddcbc2e12d92d7cd
https://doi.org/10.1016/j.jbc.2021.100549
https://doi.org/10.1016/j.jbc.2021.100549
Publikováno v:
Matrix Biology Plus, Vol 6, Iss, Pp 100038-(2020)
Matrix Biology Plus
Matrix Biology Plus
The extracellular matrix is engaged in an ever-evolving and elegant ballet of dynamic reciprocity that directly and bi-directionally regulates cell behavior. Homeostatic and pathophysiological changes in cell-matrix signaling cascades manifest as com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e0706f5167c8f3bf2dfb334f7e3546a
https://doi.org/10.1016/j.mbplus.2020.100038
https://doi.org/10.1016/j.mbplus.2020.100038
Publikováno v:
Neurobiology of Sleep and Circadian Rhythms
Neurobiology of Sleep and Circadian Rhythms, Vol 5, Iss, Pp 15-36 (2018)
Neurobiology of Sleep and Circadian Rhythms, Vol 5, Iss, Pp 15-36 (2018)
The mammalian circadian and sleep-wake systems are closely aligned through their coordinated regulation of daily activity patterns. Although they differ in their anatomical organization and physiological processes, they utilize overlapping regulatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9784b59b0d2c00d8e0ea1156b937fff4
https://pubmed.ncbi.nlm.nih.gov/31236509
https://pubmed.ncbi.nlm.nih.gov/31236509
Publikováno v:
Journal of Biotechnology
Highlights • Histidine-tagged bovine enterokinase was refolded from bacterial inclusion bodies. • Refolding yields satisfy high demands of protein crystallography projects. • Enterokinase specifically cleaved artificial propeptides from target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::587320350272afd2a36836a4353b54d3
Publikováno v:
Bioscience Reports, Vol 34, Iss 6, p e00147 (2014)
Bioscience Reports
Bioscience Reports
STS (soft tissue sarcomas) are rare malignant tumours deriving from cells of mesenchymal origin and represent only 1% of all malignant neoplasms. It has been extensively demonstrated that angiogenesis has an important role in cancer malignancy. Parti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ce7eda5bcfb7a98efbc409f79f7b540
https://doi.org/10.1042/bsr20140075
https://doi.org/10.1042/bsr20140075
Autor:
Fiorita Gonzales Lopes Mundim, Maria Lucia Hirata Katayama, Suely Nanogaki, Geertruida H. de Bock, Simone Maistro, Rosimeire Aparecida Roela, Maria Aparecida Azevedo Koike Folgueira, Maria Mitzi Brentani
Publikováno v:
Bioscience Reports
Bioscience Reports, Vol 33, Iss 6, p e00085 (2013)
Bioscience Reports, Vol 33, Iss 6, p e00085 (2013)
CAFs (cancer-associated fibroblasts), the most abundant cell type in breast cancer stroma, produce a plethora of chemokines, growth factors and ECM (extracellular matrix) proteins, that may contribute to dissemination and metastasis. Axillary nodes a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::891c1a3a0fa4e759f4c8594bfe37e682
https://doi.org/10.1042/bsr20130060
https://doi.org/10.1042/bsr20130060
Autor:
Majstorović, Ivana
Urokinazni aktivacijski sustav plazminogena je više komponentni regulatorni sustav koji ima ključnu ulogu u mnogim fiziološkim i patološkim procesima, uglavnom putem vanstanične proteolize. Sačinjen je od urokinaznog aktivatora plazminogena, nj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3908::8380576b63a647ade8abfd48857e07f2
https://repozitorij.pmf.unizg.hr/islandora/object/pmf:1037
https://repozitorij.pmf.unizg.hr/islandora/object/pmf:1037
Autor:
Klavs Dolmer, Peter G.W. Gettins
Publikováno v:
Biochemical Journal
The LRP (low-density lipoprotein receptor-related protein) can bind a wide range of structurally diverse ligands to regions composed of clusters of ~40 residue Ca2+-dependent, disulfide-rich, CRs (complement-like repeats). Whereas lysine residues fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd6536fec63e9c82a40cf3c497466df1
https://pubmed.ncbi.nlm.nih.gov/22181833
https://pubmed.ncbi.nlm.nih.gov/22181833