Zobrazeno 1 - 10
of 648
pro vyhledávání: '"tyrosine kinase inhibitors (tkis)"'
Autor:
Ying Zhang, Wei-Hui Zheng, Shi-Hong Zhou, Jia-Lei Gu, Qing Yu, Yi-Zhou Zhu, Yu-Jie Yan, Zhi Zhu, Jin-Biao Shang
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-27 (2024)
Abstract Medullary thyroid carcinoma (MTC) is a rare type of thyroid malignancy that accounts for approximately 1–2% of all thyroid cancers (TCs). MTC include hereditary and sporadic cases, the former derived from a germline mutation of rearrangeme
Externí odkaz:
https://doaj.org/article/278f910d4f0146b9afa6e31e7b63ee1f
Autor:
Vishnu Priya Veeraraghavan, Shikhar Daniel, Arun Kumar Dasari, Kaladhar Reddy Aileni, Chaitra patil, Santosh R. Patil
Publikováno v:
Oral Oncology Reports, Vol 11, Iss , Pp 100592- (2024)
This comprehensive study explored the role of epidermal growth factor receptor (EGFR)-targeted therapies in oral cancer, focusing on emerging strategies, challenges, and future directions. The EGFR signalling pathway plays a critical role in the deve
Externí odkaz:
https://doaj.org/article/5b78da09e6684f49b33fd5d27e0603f0
Autor:
Kei Morikawa, Yu Numata, Yusuke Shinozaki, Shotaro Kaneko, Aya Matsushima, Makoto Nishida, Hirotaka Kida, Hiroshi Handa, Hiroki Nishine, Masamichi Mineshita
Publikováno v:
Thoracic Cancer, Vol 15, Iss 6, Pp 496-499 (2024)
Abstract Anaplastic lymphoma kinase (ALK) fusion gene‐positive lung cancer often shows brain metastasis at initial diagnosis or during the course of treatment. However, molecular‐targeted drugs are known to pass through the blood–brain barrier
Externí odkaz:
https://doaj.org/article/0860e34e98624a1880da4cf689d2bfb3
Autor:
Piotr Domański, Jadwiga Jarosińska, Barbara Kruczyk, Mateusz Piętak, Anna Mydlak, Tomasz Demkow, Łukasz Kuncman, Marta Darewicz, Bożena Sikora-Kupis, Wojciech Michalski, Jakub Kucharz
Publikováno v:
Contemporary Oncology, Vol 27, Iss 4, Pp 242-248 (2024)
Externí odkaz:
https://doaj.org/article/ac324b6385744488a33d96c85b6e5c03
Publikováno v:
Frontiers in Chemistry, Vol 11 (2024)
Glioblastoma multiforme (GBM) is a highly aggressive malignant primary tumor in the central nervous system. Despite extensive efforts in radiotherapy, chemotherapy, and neurosurgery, there remains an inadequate level of improvement in treatment outco
Externí odkaz:
https://doaj.org/article/70e826bab88d43609369fa0a07aa7d85
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/edfafdc3548e41ca9fcd55a183a80298
Publikováno v:
Frontiers in Surgery, Vol 10 (2024)
BackgroundUsing TKIs plus anti-PD-1 antibodies combined with TACE in the treatment of patients with initially unresectable multiple HCCs has a high tumour response rate, and using laparoscopic hepatectomy (LH) combined with intraoperative RFA for rad
Externí odkaz:
https://doaj.org/article/ab3ba8ced36941c69cb2389c4963f64e
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Receptor tyrosine kinases (RTKs) play a crucial role in cellular signaling and oncogenic progression. Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs) have become the standard treatment for advanced non-small cell lung cancer (
Externí odkaz:
https://doaj.org/article/1f5281f73d9540c9aae7ef6f8d8ccdc0
Publikováno v:
Liver Research, Vol 7, Iss 2, Pp 108-115 (2023)
Local ablation technologies, such as radiofrequency ablation (RFA), microwave ablation (MWA) and cryoablation, have become a standard treatment option for hepatocellular carcinoma (HCC) less than 5 cm in size, particularly in individuals who are not
Externí odkaz:
https://doaj.org/article/5beb5897be63490a8bf4fc5a28a68d9f
Autor:
Ismail Ghafary, Chang-Kyung Kim, Eric Roth, Michael Lu, Erin M. Taub, Susan Lee, Ira Cohen, Zhongju Lu
Publikováno v:
Cardio-Oncology, Vol 9, Iss 1, Pp 1-11 (2023)
Abstract Objective To investigate the association between stages of QTc prolongation and the risk of cardiac events among patients on TKIs. Methods This was a retrospective cohort study performed at an academic tertiary care center of cancer patients
Externí odkaz:
https://doaj.org/article/cf37407463bf4ba0bb61202449cb3345