Výsledky vyhledávání - "type-VI collagen"

Akademický článek

Cartilage-derived cells display heterogeneous pericellular matrix synthesis in agarose microgels

Autor: Marloes van Mourik, Bart M. Tiemeijer, Maarten van Zon, Florencia Abinzano, Jurjen Tel, Jasper Foolen, Keita Ito

Publikováno v: Matrix Biology Plus, Vol 23, Iss , Pp 100157- (2024)

The pericellular matrix (PCM) surrounding chondrocytes is essential for articular cartilage tissue engineering. As the current isolation methods to obtain chondrocytes with their PCM (chondrons) result in a heterogeneous mixture of chondrocytes and c

Externí odkaz: https://doaj.org/article/b57a15c52a344216b4a025a821e4f13e

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Akademický článek

COL28 promotes proliferation, migration, and EMT of renal tubular epithelial cells

Autor: Linlin Li, Hong Ye, Qiaoling Chen, Lixin Wei

Publikováno v: Renal Failure, Vol 45, Iss 1 (2023)

AbstractType XXVIII collagen (COL28) is involved in cancer and lung fibrosis. COL28 polymorphisms and mutations might be involved in kidney fibrosis, but the exact role of COL28 in renal fibrosis is unknown. This study explored the function of COL28

Externí odkaz: https://doaj.org/article/8bc929b9075a44bbabebe8916e47966a

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Akademický článek

Longitudinal serological assessment of type VI collagen turnover is related to progression in a real-world cohort of idiopathic pulmonary fibrosis

Autor: Henrik Jessen, Nils Hoyer, Thomas S. Prior, Peder Frederiksen, Sarah R. Rønnow, Morten A. Karsdal, Diana J. Leeming, Elisabeth Bendstrup, Jannie M. B. Sand, Saher B. Shaker

Publikováno v: BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-8 (2021)

Abstract Background Remodeling of the extracellular matrix (ECM) is a central mechanism in the progression of idiopathic pulmonary fibrosis (IPF), and remodeling of type VI collagen has been suggested to be associated with disease progression. Biomar

Externí odkaz: https://doaj.org/article/51e299aa98f7485bbe5ebc94f9457fa2

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Akademický článek

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Akademický článek

Congenital muscular dystrophy-associated inflammatory chemokines provide axes for effective recruitment of therapeutic adult stem cell into muscles

Autor: Vitali Alexeev, Jacquelyn Olavarria, Paolo Bonaldo, Luciano Merlini, Olga Igoucheva

Publikováno v: Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-15 (2020)

Abstract Background Congenital muscular dystrophies (CMD) are a clinically and genetically heterogeneous group of neuromuscular disorders characterized by muscle weakness. The two most prevalent forms of CMD, collagen VI-related myopathies (COL6RM) a

Externí odkaz: https://doaj.org/article/85d15c56570f41bba25bbfcd88db61c6

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Akademický článek

Complete Freund’s Adjuvant Induces a Fibroblast-like Synoviocytes (FLS) Metabolic and Migratory Phenotype in Resident Fibroblasts of the Inoculated Footpad at the Earliest Stage of Adjuvant-Induced Arthritis

Autor: Susana Aideé González-Chávez, Eduardo Chaparro-Barrera, María Fernanda Alvarado-Jáquez, Rubén Cuevas-Martínez, Rosa Elena Ochoa-Albíztegui, César Pacheco-Tena

Publikováno v: Cells, Vol 12, Iss 6, p 842 (2023)

The fibroblast-like synoviocytes (FLS) have a crucial role in the pathogenesis of Rheumatoid Arthritis (RA); however, its precise mechanisms remain partially unknown. The involvement of the fibroblast in activating adjuvant-induced arthritis (AA) has

Externí odkaz: https://doaj.org/article/a36073de5c864a1b9c7e14a4eb59560c

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Akademický článek

ILC2 Lung-Homing in Cystic Fibrosis Patients: Functional Involvement of CCR6 and Impact on Respiratory Failure

Autor: Anja Schulz-Kuhnt, Vicky Greif, Kai Hildner, Lisa Knipfer, Michael Döbrönti, Sabine Zirlik, Florian Fuchs, Raja Atreya, Sebastian Zundler, Rocío López-Posadas, Clemens Neufert, Andreas Ramming, Alexander Kiefer, Anika Grüneboom, Erwin Strasser, Stefan Wirtz, Markus F. Neurath, Imke Atreya

Publikováno v: Frontiers in Immunology, Vol 11 (2020)

Cystic fibrosis patients suffer from a progressive, often fatal lung disease, which is based on a complex interplay between chronic infections, locally accumulating immune cells and pulmonary tissue remodeling. Although group-2 innate lymphoid cells

Externí odkaz: https://doaj.org/article/b9a2b170082845fa8e41cb11a39c42f7

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Akademický článek

Direct Perfusion Improves Redifferentiation of Human Chondrocytes in Fibrin Hydrogel with the Deposition of Cartilage Pericellular Matrix

Autor: Alexandre Dufour, Frédéric Mallein-Gerin, Emeline Perrier-Groult

Publikováno v: Applied Sciences, Vol 11, Iss 19, p 8923 (2021)

Articular cartilage has limited potential for self-repair, and cell-based strategies combining scaffolds and chondrocytes are currently used to treat cartilage injuries. However, achieving a satisfying level of cell redifferentiation following expans

Externí odkaz: https://doaj.org/article/9c0d868128254d1db5d8a3f589ff7a09

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Cadherin-11 Influences Differentiation in Human Mesenchymal Stem Cells by Regulating the Extracellular Matrix Via the TGFβ1 Pathway

Autor: Fiona R Passanha, Thomas Geuens, Vanessa L S LaPointe

Publikováno v: Stem Cells, 40(7), 669-677. Wiley

For regenerative medicine, directing stem cell fate is one of the key aims. Human mesenchymal stem cells (hMSCs) are versatile adult stem cells that have been proposed for several clinical applications, making directing their fate of utmost importanc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff001ae674a6f8886b2243fb9dfa658
https://doi.org/10.1093/stmcls/sxac026

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