Genomic and Metabolite Profiling Reveal a Novel Streptomyces Strain, QHH-9511, from the Qinghai-Tibet Plateau

Autor: Xi-Long Feng, Rui-Qi Zhang, Da-Cheng Wang, Wei-Ge Dong, Zhen-Xin Wang, Yi-Jie Zhai, Wen-Bo Han, Xia Yin, Junmian Tian, Jing Wei, Jin-Ming Gao, Jianzhao Qi

Publikováno v: Microbiology Spectrum, Vol 11, Iss 1 (2023)

ABSTRACT The prevalence of superbugs, represented by methicillin-resistant Staphylococcus aureus (MRSA), has become a serious clinical and public safety concern with rising incidence in hospitals. Polyketides with diverse chemical structures harbor m

Externí odkaz: https://doaj.org/article/b7ab50acec8644bdb239a78180d2a866

Novel Fredericamycin Variant Overproduced by a Streptomycin-resistant subsp. Strain

Autor: Rodríguez Estévez, Marta, Myronovskyi, Maksym, Rosenkränzer, Birgit, Paululat, Thomas, Petzke, Lutz, Ristau, Jeanette, Luzhetskyy, Andriy

Publikováno v: Marine drugs
Switzerland

Streptomycetes are an important source of natural products potentially applicable in the pharmaceutical industry. Many of these drugs are secondary metabolites whose biosynthetic genes are very often poorly expressed under laboratory cultivation cond

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1146::7e73de1e94a7ad9e7f0e08e479472f0b
https://hdl.handle.net/10033/622982

Novel Fredericamycin Variant Overproduced by a Streptomycin-resistant

Autor: Marta, Rodríguez Estévez, Maksym, Myronovskyi, Birgit, Rosenkränzer, Thomas, Paululat, Lutz, Petzke, Jeanette, Ristau, Andriy, Luzhetskyy

Publikováno v: Marine Drugs

Streptomycetes are an important source of natural products potentially applicable in the pharmaceutical industry. Many of these drugs are secondary metabolites whose biosynthetic genes are very often poorly expressed under laboratory cultivation cond

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0c5497f6b14746477bae6829b2b297ea
https://pubmed.ncbi.nlm.nih.gov/32481766

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Novel Fredericamycin Variant Overproduced by a Streptomycin-resistant Streptomyces albus subsp. chlorinus Strain.

Autor: Rodríguez Estévez M; Pharmazeutische Biotechnologie, Universität des Saarlandes, 66123 Saarbrücken, Germany., Myronovskyi M; Pharmazeutische Biotechnologie, Universität des Saarlandes, 66123 Saarbrücken, Germany., Rosenkränzer B; Pharmazeutische Biotechnologie, Universität des Saarlandes, 66123 Saarbrücken, Germany., Paululat T; Organische Chemie II, Universität Siegen, 57068 Siegen, Germany., Petzke L; BASF SE, 67056 Ludwigshafen, Germany., Ristau J; BASF SE, 67056 Ludwigshafen, Germany., Luzhetskyy A; Pharmazeutische Biotechnologie, Universität des Saarlandes, 66123 Saarbrücken, Germany.; Helmholtz-Institut für Pharmazeutische Forschung Saarland, 66123 Saarbrücken, Germany.

Publikováno v: Marine drugs [Mar Drugs] 2020 May 28; Vol. 18 (6). Date of Electronic Publication: 2020 May 28.