Zobrazeno 1 - 10
of 6 389
pro vyhledávání: '"type I-interferon"'
Autor:
Rania S. Nageeb, Noura Mostafa Mohamed, Ahmad Sallam Soliman, Amany M. Ebaid, Nancy Abdelhamid Mohammad
Publikováno v:
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, Vol 60, Iss 1, Pp 1-5 (2024)
Abstract Background Data regarding the relation between serum myostatin level, type I interferon-inducible gene expression and insulin resistance in dermatomyositis patients are limited. This study aimed to assess serum myostatin level, homeostatic m
Externí odkaz:
https://doaj.org/article/ca6f31dff680443298c004ad4f7eec91
Autor:
Laura Vízkeleti, Orsolya Papp, Viktória Doma, Jeovanis Gil, György Markó-Varga, Szonja A. Kovács, Balázs Győrffy, Sarolta Kárpáti, József Tímár
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Malignant melanoma is a difficult-to-treat skin cancer with increasing incidence worldwide. Although type-I interferon (IFN) is no longer part of guidelines, several melanoma patients are treated with type-I interferon (IFN) at some point of
Externí odkaz:
https://doaj.org/article/c19738d85de242578f64a9a66457ea73
Autor:
Takumi Saito, Ryo Takatsuji, Goh Murayama, Yu Yamaji, Yukitomo Hagiwara, Yujin Nishioka, Taiga Kuga, Tomoko Miyashita, Makio Kusaoi, Naoto Tamura, Ken Yamaji
Publikováno v:
Immunological Medicine, Vol 47, Iss 4, Pp 264-274 (2024)
Type I interferons (IFN-Is) play a significant role in systemic lupus erythematosus (SLE) pathogenesis. Double-filtration plasmapheresis (DFPP) is a treatment option for SLE; however, its effect on IFN-Is remains unclear. Therefore, we investigated t
Externí odkaz:
https://doaj.org/article/f27e8e2e68fc4fa0ad5b2806c3934536
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-18 (2024)
Abstract Bluetongue virus (BTV) infection induces profound and intricate changes in the transcriptional profile of the host to facilitate its survival and replication. However, there have been no whole-transcriptome studies on ovine lung microvascula
Externí odkaz:
https://doaj.org/article/a0cb309997c44700bb4f5d540b2bc1a8
Autor:
Chen Mengke, Zhang Yutong, Shi Weiwen, Song Xuejiao, Yang Yue, Hou Guojun, Ding Huihua, Chen Sheng, Yang Wanling, Shen Nan, Cui Yong, Zuo Xianbo, Tang Yuanjia
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 56, Pp 1659-1672 (2024)
Through genome-wide association studies (GWAS) and integrated expression quantitative trait locus (eQTL) analyses, numerous susceptibility genes (“eGenes”, whose expressions are significantly associated with common variants) associated with syste
Externí odkaz:
https://doaj.org/article/402003b49c064160aebaa145a314e194
Autor:
Wenfeng He, Hongtao Chang, Chen Li, Chenlong Wang, Longxi Li, Guoqing Yang, Jing Chen, Huimin Liu
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-17 (2024)
Abstract Serine/threonine kinase receptor-associated protein (STRAP) serves as a scaffold protein and is engaged in a variety of cellular activities, although its importance in antiviral innate immunity is unknown. We discovered that STRAP works as a
Externí odkaz:
https://doaj.org/article/0c9f80c5a4bf4a5fbf61616e629fd137
Publikováno v:
Guangdong nongye kexue, Vol 51, Iss 7, Pp 151-160 (2024)
【Objective】Tembusu virus (TMUV) disease is an important infectious disease in waterfowl. In previous studies, we found that in the early stages of TMUV infection in ducks, the viral copy number of group 2 TMUV in organs such as the liver, kidney,
Externí odkaz:
https://doaj.org/article/d606c75e1f364346a76b617122c9f746
Publikováno v:
Jichu yixue yu linchuang, Vol 44, Iss 7, Pp 959-964 (2024)
Objective To explore the role of DExD/H box helicase 60(DDX60) in the development of systemic lupus erythematosus (SLE) by regulating the dsDNA-cGAS-IFN-Ⅰ pathway. Methods Differences in DDX60 mRNA level in peripheral blood mononuclear cells (PBMCs
Externí odkaz:
https://doaj.org/article/5d1a7df73a7249a6994b8a5b66bde0e9
Autor:
Matilde Monti, Giorgia Ferrari, Luisa Gazzurelli, Mattia Bugatti, Fabio Facchetti, William Vermi
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-31 (2024)
Abstract Plasmacytoid dendritic cells (pDCs) are multifaceted immune cells executing various innate immunological functions. Their first line of defence consists in type I interferons (I-IFN) production upon nucleic acids sensing through endosomal To
Externí odkaz:
https://doaj.org/article/21418063ec4a404386de06f21aa6706c
Autor:
Wanshuang Luo, Wenjun Cai, Anchun Cheng, Mingshu Wang, Shun Chen, Juan Huang, Qiao Yang, Ying Wu, Di Sun, Dekang Zhu, Mafeng Liu, Xinxin Zhao, Shaqiu Zhang, Xumin Ou, Bin Tian, Zhongqiong Yin, Renyong Jia
Publikováno v:
Poultry Science, Vol 103, Iss 12, Pp 104269- (2024)
ABSTRACT: N-myc and STAT interactor (NMI) is an interferon-induced protein, which plays a variety of biological functions by participating in signal transduction and transcriptional activation, it has been reported to regulate antiviral response of d
Externí odkaz:
https://doaj.org/article/9bd8bac3001b4098b7ae84661960502c