Zobrazeno 1 - 10
of 53
pro vyhledávání: '"type I toxin"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Bacterial dormancy is marked by reduced cellular activity and the suspension of growth. It represents a valuable strategy to survive stressful conditions, as exemplified by the long-term tolerance towards antibiotics that is attributable to
Externí odkaz:
https://doaj.org/article/a8c83c82c92b48b39b189dcf9f0092e1
Publikováno v:
mSystems, Vol 9, Iss 7 (2024)
ABSTRACT Bacterial chromosomal type I toxin-antitoxin systems consist of a small protein, typically under 60 amino acids, and a small RNA (sRNA) that represses toxin translation. These gene pairs have gained attention over the last decade for their c
Externí odkaz:
https://doaj.org/article/baf359e97d0044c2a99430b3e94dcbf3
Akademický článek
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Akademický článek
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Publikováno v:
Toxins, Vol 15, Iss 1, p 32 (2022)
Chromosomally encoded toxin-antitoxin systems have been increasingly identified and characterized across bacterial species over the past two decades. Overproduction of the toxin gene results in cell growth stasis or death for the producing cell, but
Externí odkaz:
https://doaj.org/article/d8a5609c35a54045a164822217bc9400
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
In bacterial cells we find a variety of interacting macromolecules, among them RNAs and proteins. Not only small regulatory RNAs (sRNAs), but also small proteins have been increasingly recognized as regulators of bacterial gene expression. An average
Externí odkaz:
https://doaj.org/article/f365d2985137412794291bf4d9fbd360
Autor:
Robin C. Friedman, Stefan Kalkhof, Olivia Doppelt-Azeroual, Stephan A. Mueller, Martina Chovancová, Martin von Bergen, Benno Schwikowski
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-21 (2017)
Abstract Background While eukaryotic noncoding RNAs have recently received intense scrutiny, it is becoming clear that bacterial transcription is at least as pervasive. Bacterial small RNAs and antisense RNAs (sRNAs) are often assumed to be noncoding
Externí odkaz:
https://doaj.org/article/85e1df008b3d4322be46ef83c2a04677
Publikováno v:
Toxins, Vol 13, Iss 5, p 329 (2021)
A majority of toxins produced by type I toxin–antitoxin (TA-1) systems are small membrane-localized proteins that were initially proposed to kill cells by forming non-specific pores in the cytoplasmic membrane. The examination of the effects of num
Externí odkaz:
https://doaj.org/article/d41f8151fc7942dd8190257e899c8611
Autor:
Keith Weaver
Publikováno v:
Toxins, Vol 12, Iss 8, p 474 (2020)
The parpAD1 locus was the first type I toxin–antitoxin (TA) system described in Gram-positive bacteria and was later determined to be the founding member of a widely distributed family of plasmid- and chromosomally encoded TA systems. Indeed, homol
Externí odkaz:
https://doaj.org/article/861b00fa64974dfb8ed1ed3d19dcf786
Autor:
Jia Wen, Elizabeth M. Fozo
Publikováno v:
Toxins, Vol 6, Iss 8, Pp 2310-2335 (2014)
Bacterial toxin-antitoxin loci consist of two genes: one encodes a potentially toxic protein, and the second, an antitoxin to repress its function or expression. The antitoxin can either be an RNA or a protein. For type I and type III loci, the antit
Externí odkaz:
https://doaj.org/article/21d90b5a019549b09c9946d1ba5fd697