Zobrazeno 1 - 10
of 3 518
pro vyhledávání: '"type I error"'
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-21 (2024)
Abstract Background Jointly analyzing multiple phenotype/traits may increase power in genetic association studies by aggregating weak genetic effects. The chance that at least one phenotype is missing increases exponentially as the number of phenotyp
Externí odkaz:
https://doaj.org/article/e1ba9f6a769a4e7c824390eb8e368826
Publikováno v:
AIMS Mathematics, Vol 9, Iss 11, Pp 30710-30727 (2024)
Linear mixed-effects models (LMEMs) are widely used in medical, engineering, and social applications. The accurate specification of the covariance matrix structure within the error term is known to impact the estimation and inference procedures. Thus
Externí odkaz:
https://doaj.org/article/fd6e330479d34e4bb73295e2a2524dbd
Publikováno v:
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract Purpose In the context of clinical research, there is an increasing need for new study designs that help to incorporate already available data. With the help of historical controls, the existing information can be utilized to support the new
Externí odkaz:
https://doaj.org/article/c1d5364c5bae4dfa8d00c652d8d4e357
Autor:
Mark Rubin
Publikováno v:
Methods in Psychology, Vol 10, Iss , Pp 100140- (2024)
During multiple testing, researchers often adjust their alpha level to control the familywise error rate for a statistical inference about a joint union alternative hypothesis (e.g., “H1,1 or H1,2”). However, in some cases, they do not make this
Externí odkaz:
https://doaj.org/article/427725e3699b456c87e5154a74177121
Autor:
Babak Choodari-Oskooei, Alexandra Blenkinsop, Kelly Handley, Thomas Pinkney, Mahesh K. B. Parmar
Publikováno v:
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Multi-arm multi-stage (MAMS) randomised trial designs have been proposed to evaluate multiple research questions in the confirmatory setting. In designs with several interventions, such as the 8-arm 3-stage ROSSINI-2 trial for pre
Externí odkaz:
https://doaj.org/article/f169275c95354f73bdb833b5346d695c
Publikováno v:
Indian Journal of Psychiatry, Vol 66, Iss 5, Pp 472-476 (2024)
In research, outcomes are often categorized as primary and secondary. The primary outcome is the most important one; it determines whether the study is considered ‘successful’ or not. Secondary outcomes are chosen because they provide supporting
Externí odkaz:
https://doaj.org/article/db38d20a4dfd4ab3b10edb138315b7e7
Publikováno v:
Royal Society Open Science, Vol 11, Iss 8 (2024)
Statistical significance of both the original and the replication study is a commonly used criterion to assess replication attempts, also known as the two-trials rule in drug development. However, replication studies are sometimes conducted although
Externí odkaz:
https://doaj.org/article/20f4f889a3b2406480fc2f27ce8a0781
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Count time series (e.g., daily deaths) are a very common type of data in environmental health research. The series is generally autocorrelated, while the widely used generalized linear model is based on the assumption of independe
Externí odkaz:
https://doaj.org/article/04b4d5bf2b804ec3bb27a2835d339136
Autor:
Divyangkumar Patel
Publikováno v:
National Journal of Community Medicine, Vol 15, Iss 06 (2024)
Sample size estimation remains as a cornerstone in the meticulous planning and execution of clinical trials, pivotal for ensuring studies possess the requisite statistical power to discern meaningful treatment effects. Insufficient sample sizes compr
Externí odkaz:
https://doaj.org/article/699b69361b7d4f548133cda1194f567d
Publikováno v:
Medicine Science, Vol 12, Iss 4, Pp 1180-4 (2023)
In this study, the effect of multicollinearity, which is defined as high correlation, on the type I error rate and test power of the binary logistic regression models were studied. To do this, one dependent variable that consists of 1 and 2 and four
Externí odkaz:
https://doaj.org/article/2a8cb7ccfafe4bb6a51c387723609e43