Zobrazeno 1 - 10
of 234
pro vyhledávání: '"type 2 innate lymphoid cells"'
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-33 (2024)
Abstract Allergic rhinitis (AR) is a condition with limited treatment options. This study investigates the potential use of mesenchymal stem cell (MSC) nanovesicles as a novel therapy for AR. Specifically, the study explores the underlying mechanisms
Externí odkaz:
https://doaj.org/article/90fff321eb9d4d05b4877981666a1d61
Publikováno v:
Immunity, Inflammation and Disease, Vol 12, Iss 6, Pp n/a-n/a (2024)
Abstract Background The PI3K/Akt/mTOR pathway and autophagy are important physiological processes. But their roles in eCRSwNP remains controversial. Methods In this study, we used the eCRSwNP mouse model, PI3K/Akt/mTOR pathway inhibitors, and autopha
Externí odkaz:
https://doaj.org/article/32b9fd1d82e24203b6a2b3852b14e0c3
Autor:
Iryna Saranchova, Clara Wenjing Xia, Stephanie Besoiu, Pablo L. Finkel, Samantha L. S. Ellis, Suresh Kari, Lonna Munro, Cheryl G. Pfeifer, Ladan Fazli, Martin E. Gleave, Wilfred A. Jefferies
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Cell-based cancer immunotherapy has achieved significant advancements, providing a source of hope for cancer patients. Notwithstanding the considerable progress in cell-based immunotherapy, the persistently low response rates and the exorbitant costs
Externí odkaz:
https://doaj.org/article/84770b6c7e8544bcacd0fa5532f52bcb
Publikováno v:
BMC Pulmonary Medicine, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Backgroud Recent research has focused on the role of immune cells and immune responses in the pathogenesis of bronchopulmonary dysplasia (BPD), but the exact mechanisms have not yet been elucidated. Previously, the key roles of type 2 innate
Externí odkaz:
https://doaj.org/article/7a9da2dc90ae4b4fac077147502371be
Loss of SLC26A3 Results in Colonic Mucosal Immune Dysregulation via Epithelial-Immune Cell Crosstalk
Autor:
Dulari Jayawardena, Shubha Priyamvada, Takahiro Kageyama, Zachary White, Anoop Kumar, Theodor F. Griggs, Apurba Majumder, Ramsha Akram, Arivarasu N. Anbazhagan, Teruyuki Sano, Pradeep K. Dudeja
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 4, Pp 903-919 (2023)
Background & Aims: Down-regulation of chloride transporter SLC26A3 or down-regulated in adenoma (DRA) in colonocytes has recently been linked to the pathogenesis of ulcerative colitis (UC). Because exaggerated immune responses are one of the hallmark
Externí odkaz:
https://doaj.org/article/fd0b8fc91d7c4c7fa67e4275254f6641
Akademický článek
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Autor:
Rama K. Gurram, Danping Wei, Qiao Yu, Olena Kamenyeva, Hyunwoo Chung, Mingzhu Zheng, Matthew J. Butcher, Juraj Kabat, Chengyu Liu, Jaspal S. Khillan, Jinfang Zhu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
T helper-2 (Th2) cells and type 2 innate lymphoid cells (ILC2s) play crucial roles during type 2 immune responses; the transcription factor GATA3 is essential for the differentiation and functions of these cell types. It has been demonstrated that GA
Externí odkaz:
https://doaj.org/article/7086e6abc9e0457685c63d6ddf0cd319
Akademický článek
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Publikováno v:
Journal of Asthma and Allergy, Vol Volume 14, Pp 773-783 (2021)
Maryline Falquet,1,2 Giuseppe Ercolano,1,2 Peter Jandus,3 Camilla Jandus,1,2,* Sara Trabanelli1,2,* 1Ludwig Institute for Cancer Research, Lausanne Branch, Lausanne, Switzerland; 2Department of Pathology and Immunology, Faculty of Medicine, U
Externí odkaz:
https://doaj.org/article/15b6fc8753a9463c989cb6062a270a13
Publikováno v:
BMC Immunology, Vol 22, Iss 1, Pp 1-9 (2021)
Abstract Background Acute graft-versus-host disease (aGVHD) is one of the most common causes of morbidity for patients undergoing allogeneic stem cell transplantation. There is preliminary evidence that activated Group 2 innate lymphoid cells (ILC2s)
Externí odkaz:
https://doaj.org/article/15e56cec54214907a6ceb100f11901b8