Zobrazeno 1 - 10
of 490
pro vyhledávání: '"two-component regulatory systems"'
Autor:
Rahul Yadav, Deepak Kumar Saini
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 11 (2024)
ABSTRACT For bacteria, an intricate coordination between sensing and regulating iron levels and managing oxidative stress is required as their levels are tightly interlinked. While various oxidative stress and heme-based redox sensors have been repor
Externí odkaz:
https://doaj.org/article/5293398e7d284b669b9c74f746b435c5
Publikováno v:
mBio, Vol 15, Iss 7 (2024)
ABSTRACT Hybrid two-component systems (HTCSs) comprise a major class of transcription regulators of polysaccharide utilization genes in Bacteroides. Distinct from classical two-component systems in which signal transduction is carried out by intermol
Externí odkaz:
https://doaj.org/article/7ca82a07cc3e480ba273a6a88367ec61
Autor:
Agathe Faure, Sylvie Manuse, Mathilde Gonin, Christophe Grangeasse, Jean-Michel Jault, Cédric Orelle
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 2 (2024)
ABSTRACTDrug-resistant bacteria are a serious threat to human health as antibiotics are gradually losing their clinical efficacy. Comprehending the mechanism of action of antimicrobials and their resistance mechanisms plays a key role in developing n
Externí odkaz:
https://doaj.org/article/ff702f340c1149e3ad213ed54630d166
Autor:
Natalia I. García-Tomsig, Fernando M. García-Rodriguez, Sabina K. Guedes-García, Vicenta Millán, Anke Becker, Marta Robledo, José I. Jiménez-Zurdo
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTThe nitrogen (N) status transduced via the NtrBC two-component system is a major signaling cue in the root nodule endosymbiosis of diazotrophic rhizobia with legumes. NtrBC is upregulated in the N-limiting rhizosphere environment at the onset
Externí odkaz:
https://doaj.org/article/6aaa4a9c2a44465fa8c223e9a8ea1920
Autor:
Megan E. Garber, Vered Frank, Alexey E. Kazakov, Matthew R. Incha, Alberto A. Nava, Hanqiao Zhang, Luis E. Valencia, Jay D. Keasling, Lara Rajeev, Aindrila Mukhopadhyay
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTThis report presents multi-genome evidence that REC protein family expansion occurs when the emergence of new pathways gives rise to functional discordance. Specificity between residues in REC domain containing response regulators with paired
Externí odkaz:
https://doaj.org/article/1b5e31e2aab640b78a76252a4e5a2252
Autor:
Liam K. R. Sharkey, Romain Guerillot, Calum J. Walsh, Adrianna M. Turner, Jean Y. H. Lee, Stephanie L. Neville, Stephan Klatt, Sarah L. Baines, Sacha J. Pidot, Fernando J. Rossello, Torsten Seemann, Hamish E. G. McWilliam, Ellie Cho, Glen P. Carter, Benjamin P. Howden, Christopher A. McDevitt, Abderrahman Hachani, Timothy P. Stinear, Ian R. Monk
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTAmong the 16 two-component systems in the opportunistic human pathogen Staphylococcus aureus, only WalKR is essential. Like the orthologous systems in other Bacillota, S. aureus WalKR controls autolysins involved in peptidoglycan remodeling a
Externí odkaz:
https://doaj.org/article/b925679724c74489887fb31d58cddb66
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Gram-negative facultative anaerobes often cause bacteremia, a systemic infection associated with severe clinical outcomes. ArcAB, a two-component regulatory system that represses aerobic respiration, is a key mediator of metabolic adaptation
Externí odkaz:
https://doaj.org/article/db3186dd667640c39d947e61d0da2980
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 5 (2023)
ABSTRACT Bacterial two-component systems are crucial features of bacterial pathogens such as methicillin-resistant Staphylococcus aureus to overcome environmental and antimicrobial stresses by activating regulons to interfere with the bactericidal me
Externí odkaz:
https://doaj.org/article/bc44db0c2e65456ebe70a8fdfcf4d581
Akademický článek
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Autor:
Tania Henríquez, Jyh-Shiuan Hsu, Jakob Sebastian Hernandez, Sonja Kuppermann, Michelle Eder, Heinrich Jung
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT MxtR/ErdR is a two-component system that has been previously described as a regulator of the utilization of acetate in Vibrio cholerae and in some Pseudomonas species. Regulation is achieved by controlling the expression of the acs gene (ace
Externí odkaz:
https://doaj.org/article/4bfd22af5f0041e6aa99033c5720b355