Zobrazeno 1 - 10
of 633
pro vyhledávání: '"tumour- associated macrophages"'
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Objective This study aims to investigate the effect of CD206 on the progression of hepatocellular carcinoma (HCC) and the regulation of the tumour immune microenvironment. Methods A subcutaneous mouse model of HCC was established and treated
Externí odkaz:
https://doaj.org/article/8d9b821dc3da45b89f609a3c6c81e91d
Autor:
Hao-Jia Sun, Zhui-Feng Zheng, Li-Jun Zhang, Le Fang, Hua Fu, Shao-Yang Chen, Rong-Xiu Feng, Xiao-Yang Liu, Qing-Nan Tang, Xue-Wen Liu
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Objective To assess the infiltration characteristics of tumour-associated macrophages (TAMs) in buccal mucosa carcinoma (BMC) and the correlation of these features with clinicopathological factors. Materials and methods Immunohistochemistry
Externí odkaz:
https://doaj.org/article/eadf546f0307429595a7607df0a5d2ce
Autor:
Belén Toledo, Linrui Zhu Chen, María Paniagua-Sancho, Juan Antonio Marchal, Macarena Perán, Elisa Giovannetti
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-34 (2024)
Abstract Macrophages infiltrating tumour tissues or residing in the microenvironment of solid tumours are known as tumour-associated macrophages (TAMs). These specialized immune cells play crucial roles in tumour growth, angiogenesis, immune regulati
Externí odkaz:
https://doaj.org/article/04bae7a90baa4ad0a0fd1a84ab9ec11f
Autor:
Saem Mul Park, Chun-Jen J. Chen, Daniel J. Verdon, Marcus P. Y. Ooi, Anna E. S. Brooks, Richard C. W. Martin, Jon A. Mathy, Patrick O. Emanuel, P. Rod Dunbar
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Macrophages play essential roles in maintaining tissue homeostasis and immune defence. However, their extensive infiltration into tumours has been linked to adverse outcomes in multiple human cancers. Within the tumour microenvironment (TME), tumour-
Externí odkaz:
https://doaj.org/article/a187d000615349518c462ce930fe0db0
Publikováno v:
Trends in Computational and Applied Mathematics, Vol 25, Iss 1 (2024)
Melanoma is considered one of the most aggressive types of cancer due to its high propensy for metastasis, which significantly reduces survival chances when detected late. Moreover, melanoma exhibits strong immunogenic characteristics, complicating i
Externí odkaz:
https://doaj.org/article/420dada52e5e4682ab83b17916b02238
Publikováno v:
Heliyon, Vol 10, Iss 7, Pp e29273- (2024)
Background: Oesophageal squamous cell carcinoma (ESCC) is a leading cause of cancer-related deaths worldwide because existing treatments are often insufficient. Therefore, new, reliable biomarkers must be identified. CTSL overexpression is closely as
Externí odkaz:
https://doaj.org/article/025bf8e89b104351b8ba61ef24104b20
Autor:
Sai Man Cheung, Kwok-Shing Chan, Nicholas Senn, Ehab Husain, Ravi Sharma, Trevor McGoldrick, Tanja Gagliardi, Yazan Masannat, Jiabao He
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9303 (2024)
The deregulation of monounsaturated, polyunsaturated, and saturated fatty acids (MUFAs, PUFAs, SFAs) from de novo synthesis and hypoxia are central metabolic features of breast tumour. Early response markers for neoadjuvant chemotherapy (NACT) are cr
Externí odkaz:
https://doaj.org/article/0274f9d4d33947c0a017492c425ba00f
Publikováno v:
Cells, Vol 13, Iss 12, p 1057 (2024)
Diffuse large B cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma worldwide, constituting around 30–40% of all cases. Almost 60% of patients develop relapse of refractory DLBCL. Among the reasons for the therapy failure, tumour
Externí odkaz:
https://doaj.org/article/52caac3063614bb598260447be1ac577
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-22 (2023)
Abstract Tumour-associated macrophages (TAMs) are crucial components of the tumour microenvironment and play a significant role in tumour development and drug resistance by creating an immunosuppressive microenvironment. Macrophages are essential com
Externí odkaz:
https://doaj.org/article/19b1f597cfca4d45a3fbea0466afc367
Autor:
Yifan Cao, Kuan Yu, Zihao Zhang, Yun Gu, Yichao Gu, Wandi Li, Weijuan Zhang, Zhenbin Shen, Jiejie Xu, Jing Qin
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 2, Pp n/a-n/a (2024)
Abstract Background and aims In gastric cancer, the response rate of programmed cell death protein‐1 (PD‐1) inhibitor is far from satisfactory, indicating additional nonredundant pathways might hamper antitumour immunity. V‐domain immunoglobuli
Externí odkaz:
https://doaj.org/article/5842ca28560842f7b5b45c60ac353a53