Zobrazeno 1 - 10
of 138
pro vyhledávání: '"tumour vasculature"'
Autor:
Yvonne L. E. Ang, Gwo Fuang Ho, Ross A. Soo, Raghav Sundar, Sing Huang Tan, Wei Peng Yong, Samuel G. W. Ow, Joline S. J. Lim, Wan Qin Chong, Phyu Pyar Soe, Bee Choo Tai, Lingzhi Wang, Boon Cher Goh, Soo-Chin Lee
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background We previously reported that low-dose, short-course sunitinib prior to neoadjuvant doxorubicin-cyclophosphamide (AC) normalised tumour vasculature and improved perfusion, but resulted in neutropenia and delayed subsequent cycles in
Externí odkaz:
https://doaj.org/article/64ad21aacf0e4e9dbb97e7c6812136d7
Akademický článek
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Autor:
Yanfei Qi, Jinbiao Chen, Jennifer R. Gamble, Yang Zhao, Ka Ka Ting, Mathew A. Vadas, Paul R. Coleman
Publikováno v:
Cancers
Cancers, Vol 13, Iss 1724, p 1724 (2021)
Cancers, Vol 13, Iss 1724, p 1724 (2021)
Simple Summary Tumour blood vessels, characterised by abnormal morphology and function, create an immunosuppressive tumour microenvironment via restricting the appropriate leucocyte subsets trafficking. Strategies to trigger phenotypic alteration in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41b25e571dab28ddba4c4e2900ddc988
http://europepmc.org/articles/PMC8038724
http://europepmc.org/articles/PMC8038724
Autor:
Kay Khine Myo Min, Claudine S. Bonder, Michaelia P. Cockshell, Derek Abbott, Emma J. Thompson, Mohsen Dorraki, Andrew Allison, Anahita Fouladzadeh, Johan W. Verjans
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Communications Biology
Communications Biology
The growth of solid tumours relies on an ever-increasing supply of oxygen and nutrients that are delivered via vascular networks. Tumour vasculature includes endothelial cell lined angiogenesis and the less common cancer cell lined vasculogenic mimic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2877cb5a65fb3d18197342589bcb0a82
https://hdl.handle.net/11541.2/27487
https://hdl.handle.net/11541.2/27487
Autor:
Lingzhi Wang, Gwo Fuang Ho, Yvonne Ang, Soo-Chin Lee, Bee Choo Tai, Ross A. Soo, Samuel Guan Wei Ow, Joline S.J. Lim, Sing Huang Tan, Wan Qin Chong, Boon Cher Goh, Raghav Sundar, Phyu Pyar Soe, Wei Peng Yong
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
BMC Cancer
BMC Cancer
BackgroundWe previously reported that low-dose, short-course sunitinib prior to neoadjuvant doxorubicin-cyclophosphamide (AC) normalised tumour vasculature and improved perfusion, but resulted in neutropenia and delayed subsequent cycles in breast ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a73a38445a06aef1681dd2120158331
https://doi.org/10.1186/s12885-020-07616-4
https://doi.org/10.1186/s12885-020-07616-4
Autor:
Emma J. Thompson, Carmela Martini, Emma C. Josefsson, Stephanie R. Hyslop, Brian Dale, Claudine S. Bonder, Anthony E. Woods, Lisa M. Ebert, Michaelia P. Cockshell
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-18 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-18 (2020)
Tumour vasculature supports the growth and progression of solid cancers with both angiogenesis (endothelial cell proliferation) and vasculogenic mimicry (VM, the formation of vascular structures by cancer cells themselves) predictors of poor patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d1ff1aaff87f8266eaf43d0b08b9736
https://hdl.handle.net/11541.2/141835
https://hdl.handle.net/11541.2/141835
Akademický článek
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Autor:
Timothy W. Wallace, John A. Hadfield, Steven B. Rossington, Kaye J. Williams, Steven D. Shnyder
Publikováno v:
Rossington, S, Hadfield, J, Shnyder, S D, Wallace, T & Williams, K 2017, ' Tubulin-binding dibenz[c,e]oxepines : Part 2. Structural variation and biological evaluation as tumour vasculature disrupting agents ', Bioorganic and Medicinal Chemistry, vol. 25, no. 5, pp. 1630-1642 . https://doi.org/10.1016/j.bmc.2017.01.027
5,7-Dihydro-3,9,10,11-tetramethoxybenz[c,e]oxepin-4-ol 1, prepared from a dibenzyl ether precursor via Pd-catalysed intramolecular direct arylation, possesses broad-spectrum in vitro cytotoxicity towards various tumour cell lines, and induces vascula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7159b0428917a521e7ecb361504f199
https://doi.org/10.1016/j.bmc.2017.01.027
https://doi.org/10.1016/j.bmc.2017.01.027
Autor:
Tomaszewski, Michal Robert
Poor oxygenation of solid tumours has been linked with resistance to chemo- and radio-therapy and poor patient outcomes. Measuring the functional status of the tumour vasculature, including blood flow fluctuations and changes in oxygenation is import
Externí odkaz:
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.763747
Autor:
Pautu, Vincent
Il a été démontré que l’acidité de l’environnement tumoral jouait un rôle dans la résistance aux chimiothérapies. L’utilisation de nanovecteurs, tels que les nanocapsules lipidiques (LNC), permet non seulement d’améliorer le temps de
Externí odkaz:
http://www.theses.fr/2018ANGE0042