Zobrazeno 1 - 10
of 1 021
pro vyhledávání: '"tumour infiltrating lymphocytes"'
Autor:
Yikan Sun, Eloy Yinwang, Shengdong Wang, Zenan Wang, Fangqian Wang, Yucheng Xue, Wenkan Zhang, Shenzhi Zhao, Haochen Mou, Shixin Chen, Lingxiao Jin, Binghao Li, Zhaoming Ye
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-21 (2024)
Abstract CD8+ T cells are the workhorses executing adaptive anti-tumour response, and targets of various cancer immunotherapies. Latest advances have unearthed the sheer heterogeneity of CD8+ tumour infiltrating lymphocytes, and made it increasingly
Externí odkaz:
https://doaj.org/article/fdda9f8f7434471a9afa3fccca6f7920
Autor:
Tanjina Kader, Elena Provenzano, Madawa W. Jayawardana, Shona Hendry, Jia-Min Pang, Kenneth Elder, David J. Byrne, Lauren Tjoeka, Helen ML. Frazer, Eloise House, Sureshni I. Jayasinghe, Holly Keane, Anand Murugasu, Neeha Rajan, Islam M. Miligy, Michael Toss, Andrew R. Green, Emad A. Rakha, Stephen B. Fox, G. Bruce Mann, Ian G. Campbell, Kylie L. Gorringe
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-10 (2024)
Abstract Various histopathological, clinical and imaging parameters have been evaluated to identify a subset of women diagnosed with lesions with uncertain malignant potential (B3 or BIRADS 3/4A lesions) who could safely be observed rather than being
Externí odkaz:
https://doaj.org/article/b48a3f6e9ea54a189ccefd102db6473b
Autor:
Chin-King Looi, Ee-Mun Loo, Heng-Chee Lim, Yik-Ling Chew, Kok-Yong Chin, Shiau-Chuen Cheah, Bey Hing Goh, Chun-Wai Mai
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Nasopharyngeal carcinoma (NPC) is a distinct malignancy of the nasopharynx and is consistently associated with the Epstein-Barr virus (EBV) infection. Its unique anatomical location and complex aetiology often result in advanced-stage disease at firs
Externí odkaz:
https://doaj.org/article/4cef446874884264a4edf8ef291c940c
Autor:
Aleksandra Ciarka, Michał Kunc, Marta Popęda, Aleksandra Łacko, Barbara Radecka, Marcin Braun, Joanna Pikiel, Maria Litwiniuk, Katarzyna Pogoda, Ewa Iżycka-Świeszewska, Anna Zeller, Magdalena Niemira, Rafał Pęksa, Wojciech Biernat, Elżbieta Senkus
Publikováno v:
Contemporary Oncology, Vol 28, Iss 1, Pp 75-83 (2024)
Externí odkaz:
https://doaj.org/article/747de89e46a2493a8139c1c93606b528
Autor:
Joel Kidman, Rachael M. Zemek, John-William Sidhom, Debora Correa, Nicola Principe, Fezaan Sheikh, Vanessa S. Fear, Catherine A. Forbes, Abha Chopra, Louis Boon, Ayham Zaitouny, Emma de Jong, Robert A. Holt, Matt Jones, Michael J. Millward, Timo Lassmann, Alistair R.R. Forrest, Anna K. Nowak, Mark Watson, Richard A. Lake, W. Joost Lesterhuis, Jonathan Chee
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
ABSTRACTImmune checkpoint therapy (ICT) causes durable tumour responses in a subgroup of patients, but it is not well known how T cell receptor beta (TCRβ) repertoire dynamics contribute to the therapeutic response. Using murine models that exclude
Externí odkaz:
https://doaj.org/article/f60545e051804f9796499b61db90824e
Autor:
Julie Lecuelle, Caroline Truntzer, Debora Basile, Luigi Laghi, Luana Greco, Alis Ilie, David Rageot, Jean-François Emile, Fréderic Bibeau, Julien Taïeb, Valentin Derangere, Come Lepage, François Ghiringhelli
Publikováno v:
EBioMedicine, Vol 105, Iss , Pp 105207- (2024)
Summary: Background: T-cell immune infiltrates are robust prognostic variables in localised colon cancer. Evaluation of prognosis using artificial intelligence is an emerging field. We evaluated whether machine learning analysis improved prediction o
Externí odkaz:
https://doaj.org/article/f4866831da2d49b389ebad9f61f0d2b7
Autor:
Melanie Machiels, Redouane Oulkadi, Trine Tramm, Shane R. Stecklein, Navita Somaiah, Alex De Caluwé, Jonathan Klein, William T. Tran, Roberto Salgado
Publikováno v:
Breast, Vol 71, Iss , Pp 13-21 (2023)
Radiation therapy (RT) has long been fundamental for the curative treatment of breast cancer. While substantial progress has been made in the anatomical and technological precision of RT delivery, and some approaches to de-escalate or omit RT based o
Externí odkaz:
https://doaj.org/article/d5afeaacfc5942c99871c6665e2d94b3
Autor:
Gizem Oner, Glenn Broeckx, Christophe Van Berckelaer, Karen Zwaenepoel, Sevilay Altintas, Zafer Canturk, Wiebren Tjalma, Zwi Berneman, Marc Peeters, Patrick Pauwels, Peter A. vanDam
Publikováno v:
Cancer Medicine, Vol 12, Iss 17, Pp 17901-17913 (2023)
Abstract Background Oestrogen receptor positive (ER+)/HER‐2 negative breast cancer (BC) is considered to be an immunologically cold tumour compared to triple negative breast cancer. Therefore, the tumour microenvironment (TME) of ER+/HER‐2 negati
Externí odkaz:
https://doaj.org/article/191b42cd16644c468f4e0ac985be28d8
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-18 (2023)
Abstract Background Tumour-infiltrating lymphocytes (TILs), including T and B cells, have been demonstrated to be associated with tumour progression. However, the different subpopulations of TILs and their roles in breast cancer remain poorly underst
Externí odkaz:
https://doaj.org/article/285c7edfa62c41228d226bef30b3f707
Publikováno v:
Journal of Bone Oncology, Vol 44, Iss , Pp 100518- (2024)
Background: As compared to endocrine responsive breast cancer bone is less frequent site of distant recurrence in triple-negative breast cancer (TNBC). A biomarker which predicts bone recurrence would allow a more personalized treatment approach with
Externí odkaz:
https://doaj.org/article/008c4d1ddc4b4b6c8bb13a5cb22f6635