Zobrazeno 1 - 10
of 562
pro vyhledávání: '"tumour‐stroma"'
Autor:
Camille Verocq, Jean-Christophe Noël, Manon Charry, Egor Zindy, Sandrine Rorive, Isabelle Salmon, Christine Decaestecker, Xavier Catteau
Publikováno v:
Heliyon, Vol 10, Iss 22, Pp e40295- (2024)
Background: Previous breast carcinoma studies focused on the evaluation of tumour-infiltrating lymphocytes (TILs) or of tumoural stroma via the tumour stroma ratio (TSR). Few studies assessed peritumoural lymphocytes and almost no studies investigate
Externí odkaz:
https://doaj.org/article/c33b8ca817cd4db7a1eecebd34874f80
Autor:
Selas T. F. Bots, Tom J. Harryvan, Christianne Groeneveldt, Priscilla Kinderman, Vera Kemp, Nadine vanMontfoort, Rob C. Hoeben
Publikováno v:
Molecular Oncology, Vol 18, Iss 5, Pp 1245-1258 (2024)
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy which shows unparalleled therapeutic resistance due to its genetic and cellular heterogeneity, dense stromal tissue, and immune‐suppressive tumour microenvironment. Oncolytic
Externí odkaz:
https://doaj.org/article/363926a725884353876c3b3369ba04bb
Autor:
Verocq, Camille a, b, ⁎, Noël, Jean-Christophe a, Charry, Manon b, Zindy, Egor c, Rorive, Sandrine a, b, Salmon, Isabelle a, b, c, Decaestecker, Christine c, d, Catteau, Xavier a, b
Publikováno v:
In Heliyon 30 November 2024 10(22)
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-22 (2024)
Abstract Macrophages and tumour stroma cells account for the main cellular components in the tumour microenvironment (TME). Current advancements in single-cell analysis have revolutionized our understanding of macrophage diversity and macrophage–st
Externí odkaz:
https://doaj.org/article/eed2b448d7a147eb99adfa1eeb11e5ed
Autor:
Libo Liu, Longhao Xu, Daqin Wu, Yingying Zhu, Xiaoyang Li, Chunru Xu, Ke Chen, Yi Lin, Jianwen Lao, Peicong Cai, Xuesong Li, Yun Luo, Xiang Li, Jian Huang, Tianxin Lin, Wenlong Zhong
Publikováno v:
EBioMedicine, Vol 104, Iss , Pp 105152- (2024)
Summary: Background: The tumour stroma is associated with unfavourable prognosis in diverse solid tumours, but its prognostic and predictive value in bladder cancer (BCa) is unclear. Methods: In this multicentre, retrospective study, we included 830
Externí odkaz:
https://doaj.org/article/aafd0ab8cf7043799aa1f86fbe5699c5
Autor:
N.G. Reitsam, B. Grosser, J.S. Enke, W. Mueller, A. Westwood, N.P. West, P. Quirke, B. Märkl, H.I. Grabsch
Publikováno v:
Translational Oncology, Vol 44, Iss , Pp 101913- (2024)
Background: Stroma AReactive Invasion Front Areas (SARIFA) is a novel prognostic histopathologic biomarker measured at the invasive front in haematoxylin & eosin (H&E) stained colon and gastric cancer resection specimens. The aim of the current study
Externí odkaz:
https://doaj.org/article/c36b7af027b44aac8bdd434203ca1947
Autor:
Deniz Bakkalci, Georgina Al-Badri, Wei Yang, Andy Nam, Yan Liang, Syed Ali Khurram, Susan Heavey, Stefano Fedele, Umber Cheema
Publikováno v:
Materials Today Bio, Vol 24, Iss , Pp 100923- (2024)
Stromal cells are key components of the tumour microenvironment (TME) and their incorporation into 3D engineered tumour-stroma models is essential for tumour mimicry. By engineering tumouroids with distinct tumour and stromal compartments, it has bee
Externí odkaz:
https://doaj.org/article/977c36513ebd473c84c94da9666fe446
Autor:
Maud T. A. Strous, Ragna L. A. van der Linden, Audrey L. H. M. Gubbels, Timothy K. E. Faes, Koop Bosscha, Carolien M. Bronkhorst, Maryska L. G. Janssen-Heijnen, Adriaan P. de Bruïne, F. Jeroen Vogelaar
Publikováno v:
Molecular Medicine, Vol 29, Iss 1, Pp 1-10 (2023)
Abstract Background Within the group of node-negative colon cancer patients, presumed to have a good prognosis, a significant percentage of patients develops cancer-recurrence. Current high-risk features prove inadequate to select these particular hi
Externí odkaz:
https://doaj.org/article/dc351e63cafa456ca98c82a4c3d37b81
Publikováno v:
Biology Open, Vol 12, Iss 5 (2023)
Externí odkaz:
https://doaj.org/article/c8461e5318724063b9ee5d01e2e63025
Autor:
L. Pedrosa, I. K. Araujo, M. Cuatrecasas, G. Soy, S. López, J. Maurel, C. Sánchez-Montes, C. Montironi, T. Saurí, O. Sendino, F. M. Pérez, F. Ausania, G. Fernández-Esparrach, F. M. Espósito, E. C. Vaquero, A. Ginès
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Background: Integration of transcriptomic testing into EUS-FNA samples is a growing need for precision oncology in pancreatic ductal adenocarcinoma (PDAC). The NanoString platform is suitable for transcriptome profiling in low yield RNA samples.Metho
Externí odkaz:
https://doaj.org/article/bd781e11ebac4838b6d93f1bb894f47a