Zobrazeno 1 - 10
of 1 245
pro vyhledávání: '"tumor stem cells"'
Autor:
Jiayi Peng, Linhao Yuan, Peng Kang, Shucheng Jin, Shunchang Ma, Wenjianlong Zhou, Guijun Jia, Chuanbao Zhang, Wang Jia
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Pituitary adenomas (PAs) are the second most common intracranial tumor. While current diagnostic practices rely primarily on histological testing, they often fail to capture the molecular complexities of pituitary adenomas, unders
Externí odkaz:
https://doaj.org/article/a1d2d790d7a54794a13b8b3d82897cc7
Autor:
Wei He, Yanfang Li, Song-Bai Liu, Ying Chang, Shiyuan Han, Xingyu Han, Zixin Ma, Hesham M. Amin, Yao-Hua Song, Jin Zhou
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Acetyl CoA acetyltransferase 1 (ACAT1), a mitochondrial enzyme, is mainly involved in the formation and decomposition of ketones, isoleucine, and fatty acids. Previous clinical studies showed that mutations in the ACAT1 gene lead to ketoacidosis, Not
Externí odkaz:
https://doaj.org/article/1f9a994c0cab4d3da4cfeb64d6394a46
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
As a key factor in tumorigenesis, progression, recurrence and metastasis, the biological properties, metabolic adaptations and immune escape mechanisms of CSCs are the focus of current oncological research. CSCs possess self-renewal, multidirectional
Externí odkaz:
https://doaj.org/article/ef0f6da8c61f45d18b59ba9eeafc7d26
Autor:
Jingcun Shi, Zihui Yang, Yuhan Zhang, Ahmed Abdelrehem, Ziqian Wu, Bingqing Zhang, Meng Xiao, Shijian Zhang, Zhen Zhang, Lei Wang
Publikováno v:
Translational Oncology, Vol 40, Iss , Pp 101852- (2024)
Background: Neurofibroma type I (NF1) often presents with multiple clinical phenotypes due to mutations of NF1 gene. The aim of this study was to determine the phenotypic and therapeutic relevance of tumor microenvironment in NF1 patients. Methods: T
Externí odkaz:
https://doaj.org/article/ca075a2a27534c82a770b06f1e68c2d7
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Electromagnetic fields (EMF) are increasing in popularity as a safe and non-invasive therapy. On the one hand, it is widely acknowledged that EMF can regulate the proliferation and differentiation of stem cells, promoting the undifferentiate
Externí odkaz:
https://doaj.org/article/6ec4ed8a514649328eabf0ad249c57e4
Autor:
Linhao Yuan, Peiliang Li, Jiang Li, Jiayi Peng, Jianlong Zhouwen, Shunchang Ma, Guijun Jia, Wang Jia, Peng Kang
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-12 (2023)
Abstract Background Gonadotrophic pituitary adenoma is a major subtype of pituitary adenoma in the sellar region, but it is rarely involved in the hypersecretion of hormones into blood; thus, it is commonly regarded as “non-functioning.” Its tumo
Externí odkaz:
https://doaj.org/article/55e091dfc3e94ee4a1a384f3c7d3e74f
Publikováno v:
Taiwanese Journal of Obstetrics & Gynecology, Vol 62, Iss 1, Pp 16-21 (2023)
Objective: Research has suggested that tumor-initiating tumor stem cells are derived from normal stem cells and that tumor cells undergo progressive de-differentiation to achieve a stem cell-like state. Tumor stem cells are characterized by high prol
Externí odkaz:
https://doaj.org/article/c35c9ccb0afc4c7ea45c4abf76868695
Publikováno v:
Advances in Cancer Biology - Metastasis, Vol 7, Iss , Pp 100095- (2023)
Objectives: In tumor microenvironment (TME), cancer-associated fibroblasts (CAFs) are known to expedite cancer progression (metastasis). CAF-secreted cytokines confer a survival advantage to circulating tumor stem cells (CTSCs) (indicators of residua
Externí odkaz:
https://doaj.org/article/cb23cfd5dfcc4f449c541fbe1a381f6d
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17325 (2023)
Lung cancer is the leading cause of cancer-related death worldwide. Its high mortality is partly due to chronic inflammation that accompanies the disease and stimulates cancer progression. In this review, we analyzed recent studies and highlighted th
Externí odkaz:
https://doaj.org/article/064af6f2b01745d483aed3fe20d27278
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