POFUT1 mRNA expression as an independent prognostic parameter in muscle-invasive bladder cancer

Autor: Sarah Wahby, Jonas Jarczyk, Alexander Fierek, Jakob Heinkele, Cleo-Aron Weis, Markus Eckstein, Thomas Martini, Stefan Porubsky, Mathias Hafner, Philipp Erben

Publikováno v: Translational Oncology, Vol 14, Iss 1, Pp 100900- (2021)

Muscle-invasive bladder cancer (MIBC) is characterized by high recurrence and rapid progression. Progression is linked to changes in glycan structures and altered levels of glycosyltransferases. The relationship of mRNA expression by glycosyltransfer

Externí odkaz: https://doaj.org/article/f7d66227355846939a463a55c700128a

High performance of targeted next generation sequencing on variance detection in clinical tumor specimens in comparison with current conventional methods

Autor: Dan Su, Dadong Zhang, Kaiyan Chen, Jing Lu, Junzhou Wu, Xinkai Cao, Lisha Ying, Qihuang Jin, Yizhou Ye, Zhenghua Xie, Lei Xiong, Weimin Mao, Fugen Li

Publikováno v: Journal of Experimental & Clinical Cancer Research, Vol 36, Iss 1, Pp 1-12 (2017)

Abstract Background Next generation sequencing (NGS) is being increasingly applied for assisting cancer molecular diagnosis. However, it is still needed to validate NGS accuracy on detection of DNA alternations based on a large number of clinical sam

Externí odkaz: https://doaj.org/article/fbb9ea38d80b4ae6b0bc4ba33c91ad79

肺癌基因编辑探索研究

Autor: 谢国云(Guoyun Xie)

WES of H520 tumor samples injected with control and MECOM-KO APCs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::722510ba4412b5cd6294c770a43205ee

Bleomycin concentration in patientsʹ plasma and tumors after electrochemotherapy

Autor: Grošelj, Aleš, Bošnjak, Maša, Kržan, Mojca, Kosjek, Tina, Bottyán, Krisztina, Plešnik, Helena, farmacevtka, Jamšek, Črt, Čemažar, Maja, Kis, Erika, Serša, Gregor

Publikováno v: Pharmaceutics, vol. 13, no. 9, pp. 1324-1-1324-7, 2021.
Pharmaceutics, vol. 13, no. 9, 1324, 2021.
Pharmaceutics, str. 1324-1-1324-7, Vol. 13, no. 9, 2021
COBISS-ID: 517949977

The plasma concentration profile of bleomycin in the distribution phase of patients younger than 65 years is needed to determine the suitable time interval for efficient application of electric pulses during electrochemotherapy. Additionally, bleomyc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0889079852c647ebf1399d02e0ec8241
https://dirros.openscience.si/Dokument.php?id=20660&dn=

Aggressive PDACs show hypomethylation of repetitive elements and the execution of an intrinsic IFN program linked to a ductal cell-of-origin

Autor: Martin R. Sprick, Vera Thiel, Dieter Weichenhan, Mariam Safavi, Vanessa Vogel, Matthias Schlesner, H. Efsun Arda, Roland Eils, Jacob Insua-Rodríguez, Elisa Donato, Manuel Reitberger, Silke Weisenburger, Hsi-Yu Yen, Alexander Muckenhuber, Thilo Hackert, Wilko Weichert, Corinna Klein, Janel L. Kopp, Katja Steiger, Elyne Backx, Magdalena Büscher, Soheila Zarei, Nicole Pfarr, Steffi O. Kossi, Ilse Rooman, Matthias M. Gaida, Karnjit Sarai, Mattia Falcone, Zuguang Gu, Charles D. Imbusch, Manuel Rodríguez-Paredes, Christoph Plass, Elisa Espinet, Alex Y.L. Lee, Andreas Trumpp, Oliver Strobel, Benedikt Brors, Nathalia A. Giese

Publikováno v: Cancer Discov

Pancreatic ductal adenocarcinoma (PDAC) is characterized by extensive desmoplasia, which challenges the molecular analyses of bulk tumor samples. Here we FACS-purified epithelial cells from human PDAC and normal pancreas and derived their genome-wide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa7fdd3811080248222d78593416f559
https://hdl.handle.net/20.500.14017/1560f5a6-abc0-47a9-83f5-e73539f8b586