Zobrazeno 1 - 10
of 213
pro vyhledávání: '"tumor profiling"'
Autor:
Dörthe Schaffrin-Nabe, Anke Josten-Nabe, Andrea Tannapfel, Waldemar Uhl, Marietta Garmer, Razelle Kurzrock, Timothy Crook, Sewanti Limaye, Stefan Schuster, Darshana Patil, Merle Schaffrin, Kefah Mokbel, Rudolf Voigtmann
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Despite multiple recent advances in systemic therapy for metastatic breast cancer, cases which display suboptimal response to guideline-driven treatment are frequently seen in the clinic. Effective options for such patients are limited, particularly
Externí odkaz:
https://doaj.org/article/ee48f55e5d044d9590e11da7710ff613
Autor:
Bingqing Xie, Susan Olalekan, Rebecca Back, Naa Asheley Ashitey, Heather Eckart, Anindita Basu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2024)
Ovarian cancer is a highly heterogeneous disease consisting of at least five different histological subtypes with varying clinical features, cells of origin, molecular composition, risk factors, and treatments. While most single-cell studies have foc
Externí odkaz:
https://doaj.org/article/01bfaefd279a408a89d832fd9ef6569e
Publikováno v:
Current Problems in Cancer: Case Reports, Vol 9, Iss , Pp 100210- (2023)
Cutaneous Squamous Cell Cancer (cSCC) is the second most common Non-Melanoma Skin Cancer (NMSC) after basal cell in the United States with increasing incidence due to advanced age and screening. It predominantly occurs in the head and neck region (sc
Externí odkaz:
https://doaj.org/article/d736992cafc34618bc0bdb30174686dd
Autor:
Lucy A. Godley
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Germline predisposition to hematopoietic malignancies is more common than previously appreciated, with several clinical guidelines advocating for cancer risk testing in an expanding pool of patients. As molecular profiling of tumor cells becomes a st
Externí odkaz:
https://doaj.org/article/5f9b2f3fb6b344a39c79dcafb59e45ff
Autor:
Virginia Valentini, Valentina Silvestri, Agostino Bucalo, Giulia Conti, Mina Karimi, Linda Di Francesco, Giulia Pomati, Silvia Mezi, Bruna Cerbelli, Maria Gemma Pignataro, Arianna Nicolussi, Anna Coppa, Giulia D’Amati, Giuseppe Giannini, Laura Ottini
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
IntroductionCompared with breast cancer (BC) in women, BC in men is a rare disease with genetic and molecular peculiarities. Therapeutic approaches for male BC (MBC) are currently extrapolated from the clinical management of female BC, although the d
Externí odkaz:
https://doaj.org/article/30c1888cb4474392bf22a874b1d7d259
Publikováno v:
Current Problems in Cancer: Case Reports, Vol 8, Iss , Pp 100194- (2022)
Chordomas are rare slow-growing tumors of the bone that are locally aggressive and arise from embryonic remnants of the notochord. The clinical presentation of chordomas is dependent on the site of the neoplasm. Brain MRI remains the preferred diagno
Externí odkaz:
https://doaj.org/article/0cf2b69b819b4bca8b97e328a7bb208a
Autor:
Adeolu Z. Ogunleye, Chayanit Piyawajanusorn, Anthony Gonçalves, Ghita Ghislat, Pedro J. Ballester
Publikováno v:
Advanced Science, Vol 9, Iss 24, Pp n/a-n/a (2022)
Abstract Doxorubicin is a common treatment for breast cancer. However, not all patients respond to this drug, which sometimes causes life‐threatening side effects. Accurately anticipating doxorubicin‐resistant patients would therefore permit to s
Externí odkaz:
https://doaj.org/article/23bededaf5204aaf9bc65e9fb73c41aa
Publikováno v:
World Cancer Research Journal, Vol 9 (2022)
Objective: To examine and summarize the most discussed molecular targets for prognosis prediction in all histological subtypes of breast cancer. Materials and Methods: The contemporary view on breast cancer pathology as heterogeneous disease has chan
Externí odkaz:
https://doaj.org/article/de7abaa741574c4ea49c30bbf18fdb42
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Neuroendocrine breast cancer (NEBC) is a rare entity accounting for
Externí odkaz:
https://doaj.org/article/ea849368a7594d5092da85102915828e
Autor:
Maria Teresa Di Martino, Stefania Meschini, Katia Scotlandi, Chiara Riganti, Enrico De Smaele, Francesca Zazzeroni, Massimo Donadelli, Carlo Leonetti, Michele Caraglia
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-11 (2020)
Abstract Molecular profiling of DNA and RNA has provided valuable new insights into the genetic basis of non-malignant and malignant disorders, as well as an increased understanding of basic mechanisms that regulate human disease. Recent technologica
Externí odkaz:
https://doaj.org/article/9de877396e9b457095db2f29af5d3a24