TBK1-associated adapters TANK and AZI2 protect mice against TNF-induced cell death and severe autoinflammatory diseases.

Autor: Ujevic A; Laboratory of Immunity & Cell Communication, Division BIOCEV, First Faculty of Medicine, Charles University, Vestec, Czech Republic., Knizkova D; Laboratory of Immunity & Cell Communication, Division BIOCEV, First Faculty of Medicine, Charles University, Vestec, Czech Republic.; Laboratory of Adaptive Immunity, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic., Synackova A; Laboratory of Immunity & Cell Communication, Division BIOCEV, First Faculty of Medicine, Charles University, Vestec, Czech Republic., Pribikova M; Laboratory of Immunity & Cell Communication, Division BIOCEV, First Faculty of Medicine, Charles University, Vestec, Czech Republic., Trivic T; Laboratory of Immunity & Cell Communication, Division BIOCEV, First Faculty of Medicine, Charles University, Vestec, Czech Republic.; Department of Immunobiology, University of Lausanne, Epalinges, Switzerland., Dalinskaya A; Laboratory of Immunity & Cell Communication, Division BIOCEV, First Faculty of Medicine, Charles University, Vestec, Czech Republic., Drobek A; Laboratory of Adaptive Immunity, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic., Niederlova V; Laboratory of Adaptive Immunity, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic., Paprckova D; Laboratory of Adaptive Immunity, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.; Department of Immunobiology, University of Lausanne, Epalinges, Switzerland., De Guia R; Czech Centre for Phenogenomics and Laboratory of Transgenic Models of Diseases, Institute of Molecular Genetics of the Czech Academy of Sciences, Vestec, Czech Republic., Kasparek P; Czech Centre for Phenogenomics and Laboratory of Transgenic Models of Diseases, Institute of Molecular Genetics of the Czech Academy of Sciences, Vestec, Czech Republic., Prochazka J; Czech Centre for Phenogenomics and Laboratory of Transgenic Models of Diseases, Institute of Molecular Genetics of the Czech Academy of Sciences, Vestec, Czech Republic., Labaj J; Czech Centre for Phenogenomics and Laboratory of Transgenic Models of Diseases, Institute of Molecular Genetics of the Czech Academy of Sciences, Vestec, Czech Republic., Fedosieieva O; Czech Centre for Phenogenomics and Laboratory of Transgenic Models of Diseases, Institute of Molecular Genetics of the Czech Academy of Sciences, Vestec, Czech Republic., Roeck BF; Institute for Genetics, CECAD Cluster of Excellence, University of Cologne, Cologne, Germany., Mihola O; Laboratory of Germ Cell Development, Division BIOCEV, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic., Trachtulec Z; Laboratory of Germ Cell Development, Division BIOCEV, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic., Sedlacek R; Czech Centre for Phenogenomics and Laboratory of Transgenic Models of Diseases, Institute of Molecular Genetics of the Czech Academy of Sciences, Vestec, Czech Republic., Stepanek O; Laboratory of Adaptive Immunity, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic., Draber P; Laboratory of Immunity & Cell Communication, Division BIOCEV, First Faculty of Medicine, Charles University, Vestec, Czech Republic. peter.draber@unil.ch.; Laboratory of Adaptive Immunity, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic. peter.draber@unil.ch.; Department of Immunobiology, University of Lausanne, Epalinges, Switzerland. peter.draber@unil.ch.

Publikováno v: Nature communications [Nat Commun] 2024 Nov 19; Vol. 15 (1), pp. 10013. Date of Electronic Publication: 2024 Nov 19.

Dichotomous outcomes of TNFR1 and TNFR2 signaling in NK cell-mediated immune responses during inflammation.

Autor: McCulloch TR; Frazer Institute, The University of Queensland, Woolloongabba, Australia. timothym@uni-bonn.de.; Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, University of Bonn, Bonn, Germany. timothym@uni-bonn.de., Rossi GR; Frazer Institute, The University of Queensland, Woolloongabba, Australia., Alim L; Frazer Institute, The University of Queensland, Woolloongabba, Australia., Lam PY; Frazer Institute, The University of Queensland, Woolloongabba, Australia., Wong JKM; Frazer Institute, The University of Queensland, Woolloongabba, Australia., Coleborn E; Frazer Institute, The University of Queensland, Woolloongabba, Australia., Kumari S; Frazer Institute, The University of Queensland, Woolloongabba, Australia., Keane C; Frazer Institute, The University of Queensland, Woolloongabba, Australia.; Princess Alexandra Hospital, Woolloongabba, Australia., Kueh AJ; The Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Australia., Herold MJ; The Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Australia.; Olivia Newton-John Cancer Research Institute, Heidelberg, Australia., Wilhelm C; Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, University of Bonn, Bonn, Germany., Knolle PA; Institute of Molecular Immunology, School of Medicine and Health, Technical University of Munich, Munich, Germany., Kane L; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Wells TJ; Frazer Institute, The University of Queensland, Woolloongabba, Australia.; Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, Australia., Souza-Fonseca-Guimaraes F; Frazer Institute, The University of Queensland, Woolloongabba, Australia. f.guimaraes@uq.edu.au.

Publikováno v: Nature communications [Nat Commun] 2024 Nov 14; Vol. 15 (1), pp. 9871. Date of Electronic Publication: 2024 Nov 14.

Polymorphic Variants in the Vitamin D Receptor and Clinical Parameters of Rheumatoid Arthritis Patients Undergoing Anti-TNF Treatment.

Autor: Wielińska J; Department of Clinical Immunology, Laboratory of Clinical Immunogenetics and Pharmacogenetics, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, R. Weigla 12, 53-114 Wroclaw, Poland., Górna K; Department of Clinical Immunology, Laboratory of Clinical Immunogenetics and Pharmacogenetics, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, R. Weigla 12, 53-114 Wroclaw, Poland., Świerkot J; Department of Rheumatology and Internal Medicine, Wroclaw Medical University, Wroclaw, Poland., Bugaj B; Department of Rheumatology and Internal Medicine, Wroclaw Medical University, Wroclaw, Poland., Kolossa K; Department of Rheumatology and Connective Tissue Diseases, Jan Biziel University Hospital No. 2, Bydgoszcz, Poland., Jeka S; Department of Rheumatology and Connective Tissue Diseases, Jan Biziel University Hospital No. 2, Bydgoszcz, Poland.; Clinic and Department of Rheumatology and Connective Tissue Diseases, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Jagiellońska 15, 85-067 Bydgoszcz, Poland., Bogunia-Kubik K; Department of Clinical Immunology, Laboratory of Clinical Immunogenetics and Pharmacogenetics, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, R. Weigla 12, 53-114 Wroclaw, Poland.

Publikováno v: Archivum immunologiae et therapiae experimentalis [Arch Immunol Ther Exp (Warsz)] 2024 Nov 10; Vol. 72 (1). Date of Electronic Publication: 2024 Nov 10 (Print Publication: 2024).

Long-term follow-up of anti-TNF treatment in adult and pediatric DADA2 patients: Insights from real-world data.

Autor: Ayan G; Division of Rheumatology, Department of Internal Medicine, Medical Faculty, Hacettepe University, Ankara, Turkey.; Vasculitis Research Centre, Hacettepe University, Ankara, Turkey., Basaran O; Vasculitis Research Centre, Hacettepe University, Ankara, Turkey.; Division of Pediatric Rheumatology, Department of Pediatrics, Medical Faculty, Hacettepe University, Ankara, Turkey., Firlatan B; Division of Rheumatology, Department of Internal Medicine, Medical Faculty, Hacettepe University, Ankara, Turkey.; Vasculitis Research Centre, Hacettepe University, Ankara, Turkey., Kilic L; Division of Rheumatology, Department of Internal Medicine, Medical Faculty, Hacettepe University, Ankara, Turkey.; Vasculitis Research Centre, Hacettepe University, Ankara, Turkey., Bilginer Y; Vasculitis Research Centre, Hacettepe University, Ankara, Turkey.; Division of Pediatric Rheumatology, Department of Pediatrics, Medical Faculty, Hacettepe University, Ankara, Turkey., Alikasifoglu M; Division of Medical Genetics, Medical Faculty, Hacettepe University, Ankara, Turkey., Karadag O; Division of Rheumatology, Department of Internal Medicine, Medical Faculty, Hacettepe University, Ankara, Turkey.; Vasculitis Research Centre, Hacettepe University, Ankara, Turkey., Ozen S; Vasculitis Research Centre, Hacettepe University, Ankara, Turkey.; Division of Pediatric Rheumatology, Department of Pediatrics, Medical Faculty, Hacettepe University, Ankara, Turkey.

Publikováno v: International journal of rheumatic diseases [Int J Rheum Dis] 2024 Nov; Vol. 27 (11), pp. e15377.

Efficacy of TNF-Alpha Inhibitors to Control Inflammation and Prevent Secondary Complications in Non-Infectious Uveitis: A Real-Life Experience from Switzerland.

Autor: Fuchs D; Department of Ophthalmology, Cantonal Hospital of Lucerne, Lucerne, Switzerland., Bograd A; Berner Augenklinik, Bern, Switzerland.; Department of Ophthalmology, Bern University Hospital, Inselspital, University of Bern, Bern, Switzerland.; Department of Ophthalmology, Pallas Klink, Olten, Switzerland., Pfister IB; Berner Augenklinik, Bern, Switzerland., Bächtiger J; Berner Augenklinik, Bern, Switzerland., Spindler J; Berner Augenklinik, Bern, Switzerland.; Department of Ophthalmology University Hospital Zurich, University of Zurich, Zurich, Switzerland., Hoogewoud F; Eye Hospital, FAA, Department of Ophthalmology, University of Lausanne Jules-Gonin, Lausanne, Switzerland., Gugleta K; Department of Ophthalmology, University of Basel, Basel, Switzerland., Böni C; Department of Ophthalmology University Hospital Zurich, University of Zurich, Zurich, Switzerland.; Augenarztpraxis Bremgarten, Bremgarten, Switzerland., Guex-Crosier Y; Eye Hospital, FAA, Department of Ophthalmology, University of Lausanne Jules-Gonin, Lausanne, Switzerland., Garweg JG; Berner Augenklinik, Bern, Switzerland.; Department of Ophthalmology, Bern University Hospital, Inselspital, University of Bern, Bern, Switzerland., Tappeiner C; Department of Ophthalmology, Pallas Klink, Olten, Switzerland.; Department of Ophthalmology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.; Department of Ophthalmology, San Raffaele Scientific Institute, University Vita-Salute, Milan, Italy.; Medical Faculty, University of Bern, Bern, Switzerland.

Publikováno v: Ocular immunology and inflammation [Ocul Immunol Inflamm] 2024 Oct; Vol. 32 (8), pp. 1585-1590. Date of Electronic Publication: 2023 Oct 05.