Zobrazeno 1 - 10
of 60
pro vyhledávání: '"tumor micoenvironment"'
Autor:
Meng-Ke Liu, Feng Liu, Yu-Ting Dai, Xiang-Qin Weng, Li-Li Cheng, Li-Quan Fan, Han Liu, Lu Jiang, Xiao-Jian Sun, Hai Fang, Li Wang, Wei-Li Zhao
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Mast cell leukemia is a rare and aggressive disease, predominantly with KIT D816V mutation. With poor response to conventional poly-chemotherapy, mast cell leukemia responded to the midostaurin treatment with a 50% overall response rate (ORR), but co
Externí odkaz:
https://doaj.org/article/7bccce04824d4586b259c41c50bfc365
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
Cancer immunotherapy shows durable treatment responses and therapeutic benefits compared to other cancer treatment modalities, but many cancer patients display primary and acquired resistance to immunotherapeutics. Immunosuppressive tumor microenviro
Externí odkaz:
https://doaj.org/article/49143242d61c45bbaf252a8da6c93b51
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Cuproptosis is the most recently discovered mode of cell death. It could affect the metabolism of cancer cells and surrounding infiltrating immune cells. In recent years, many studies have also shown that the tumor microenvironment (TME) plays a crit
Externí odkaz:
https://doaj.org/article/005f105bbb8542ac9b1d426e2e692727
Autor:
Christian R. Moya-Garcia, Hideaki Okuyama, Nader Sadeghi, Jianyu Li, Maryam Tabrizian, Nicole Y. K. Li-Jessen
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The 5-year overall survival rate remains approximately 50% for head and neck (H&N) cancer patients, even though new cancer drugs have been approved for clinical use since 2016. Cancer drug studies are now moving toward the use of three-dimensional cu
Externí odkaz:
https://doaj.org/article/c33a8647c55b458f9b67f5f37c420793
Autor:
Connor T. King, Margarite D. Matossian, Jonathan J. Savoie, Khoa Nguyen, Maryl K. Wright, C. Ethan Byrne, Steven Elliott, Hope E. Burks, Melyssa R. Bratton, Nicholas C. Pashos, Bruce A. Bunnell, Matthew E. Burow, Bridgette M. Collins-Burow, Elizabeth C. Martin
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Liver kinase B1 (LKB1) is a potent tumor suppressor that regulates cellular energy balance and metabolism as an upstream kinase of the AMP-activated protein kinase (AMPK) pathway. LKB1 regulates cancer cell invasion and metastasis in multiple cancer
Externí odkaz:
https://doaj.org/article/1fca8d14259943c0915a7352775e251d
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Tumor evolution is influenced by events involving tumor cells and the environment in which they live, known as the tumor microenvironment (TME). TME is a functional and structural niche composed of tumor cells, endothelial cells (ECs), cancer-associa
Externí odkaz:
https://doaj.org/article/8839d94d74fd4129847140b296089675
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Background: Lung adenocarcinoma (LUAD) accounts for the majority of lung cancers, and the survival of patients with advanced LUAD is poor. The extracellular matrix (ECM) is a fundamental component of the tumor microenvironment (TME) that determines t
Externí odkaz:
https://doaj.org/article/fd5ed7af069d498abff5eed680aa3173
Autor:
Sanjay Mishra, Dinesh K. Ahirwar, Amit Kumar Srivastava, Prem Prakash Tripathi, Ramesh K. Ganju
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/68e792ac8e264ec392a82cee411fe0c1
Autor:
Tominaga, Kana, Minato, Hiroshi, Murayama, Takahiko, Sasahara, Asako, Nishimura, Tatsunori, Kiyokawa, Etsuko, Kanauchi, Hajime, Shimizu, Seiichiro, Sato, Ayaka, Nishioka, Kotoe, Tsuji, Ei-ichi, Yano, Masao, Ogawa, Toshihisa, Ishii, Hideshi, Mori, Masaki, Akashi, Koichi, Okamoto, Koji, Tanabe, Masahiko, Tada, Kei-ichiro, Tojo, Arinobu, Gotoh, Noriko
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2019 Jan 01. 116(2), 625-630.
Externí odkaz:
https://www.jstor.org/stable/26574075
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Metabolic reprogramming is one of the emerging hallmarks of cancer and is driven by both the oncogenic mutations and challenging microenvironment. To satisfy the demands of energy and biomass for rapid proliferation, the metabolism of various nutrien
Externí odkaz:
https://doaj.org/article/2fc94651da194b219dc127c57777cf16