Zobrazeno 1 - 10
of 364
pro vyhledávání: '"tumor immune microenvironment (time)"'
Autor:
Ning Lan, Shuheng Bai, Min Chen, Xuan Wang, Zhaode Feng, Ying Gao, Beina Hui, Wen Ma, Xiangxiang Zhang, Fengyuan Hu, Wanyi Liu, Wenyang Li, Fang Wu, Juan Ren
Publikováno v:
Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-13 (2024)
Abstract The MECOM locus is a gene frequently amplified in high-grade serous ovarian carcinoma (HGSOC). Nevertheless, the body of research examining the associations among MECOM transcripts, patient prognosis, and their role in modulating the tumor i
Externí odkaz:
https://doaj.org/article/8c9b1dd6204a4414866d7abc28d2df9b
Publikováno v:
Shanghai Jiaotong Daxue xuebao. Yixue ban, Vol 44, Iss 7, Pp 814-821 (2024)
Osteosarcoma is a common primary malignant bone tumor in adolescents and children, characterized by a high recurrence rate and metastasis, making its treatment extremely challenging. Traditional treatment modalities, including surgery, radiation ther
Externí odkaz:
https://doaj.org/article/c5559a02310e407286f675a4ce48cb10
Autor:
Jason Tasoulas, Travis P. Schrank, Harish Bharambe, Jay Mehta, Steven Johnson, Kimon Divaris, Trevor G. Hackman, Siddharth Sheth, Kedar Kirtane, Juan C. Hernandez-Prera, Christine H. Chung, Wendell G. Yarbrough, Renata Ferrarotto, Natalia Issaeva, Stamatios Theocharis, Antonio L. Amelio
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Adenoid cystic carcinoma (AdCC) is a slow-growing salivary gland malignancy that relapses frequently. AdCCs of the submandibular gland exhibit unique differences in prognosis and treatment response to adjuvant radiotherapy compared to other
Externí odkaz:
https://doaj.org/article/dcc8fd92e705442c9ebdfb5df85e4bce
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundImmunotherapy has revolutionized skin cutaneous melanoma treatment, but response variability due to tumor heterogeneity necessitates robust biomarkers for predicting immunotherapy response.MethodsWe used weighted gene co-expression network
Externí odkaz:
https://doaj.org/article/15b904924afa42c8a82a7eeefca5c68c
Autor:
Tuo Wang, Cong Cao, Yu Fan, Jialing Xu, Tao Hua, Jie Ding, Zejie Liu, Beili Wang, Juanwen Lian
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Background GABPB1, the gene that encodes two isoforms of the beta subunit of GABP, has been identified as an oncogene in multiple malignant tumors. However, the role and mode of action of GABPB1 in malignant tumors, especially in lung cancer
Externí odkaz:
https://doaj.org/article/03faa9885d4c49598923ab3940c591aa
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundTertiary lymphoid structures (TLS), ordered structure of tumor-infiltrating immune cells in tumor immune microenvironment (TIME), play an important role in the development and anti-tumor immunity of various cancers, including liver, colon,
Externí odkaz:
https://doaj.org/article/dff78a62341e4beb813d74e507509c30
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Lung squamous cell carcinoma (LUSC) is the second most common lung cancer worldwide, leading to millions of deaths annually. Although immunotherapy has expanded the therapeutic choices for LUSC and achieved considerable efficacy in a subset
Externí odkaz:
https://doaj.org/article/1d4d24951dca4eb8961edd4d14f927e0
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/91ba1c11bf1946acae0c3fcc0271f4bf
Autor:
Duo Xu, MD, PhD, Yanyun Gao, PhD, Haitang Yang, MD, PhD, Marc Spils, MD, Thomas M. Marti, PhD, Tereza Losmanová, MD, Min Su, PhD, Wenxiang Wang, MD, Qinghua Zhou, MD, Patrick Dorn, MD, Yongqian Shu, MD, PhD, Ren-Wang Peng, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 5, Pp 100672- (2024)
Introduction: Malignant pleural mesothelioma (MPM) is a rare and universally lethal malignancy with limited treatment options. Immunotherapy with immune checkpoint inhibitors (ICIs) has recently been approved for unresectable MPM, but response to ICI
Externí odkaz:
https://doaj.org/article/e39747f2ea884a66863f10c057030d43
Autor:
Christophe Van Berckelaer, Steven Van Laere, Seayoung Lee, Michael A Morse, Joseph Geradts, Luc Dirix, Mark Kockx, François Bertucci, Peter Van Dam, Gayathri R Devi
Publikováno v:
Translational Oncology, Vol 43, Iss , Pp 101907- (2024)
Objective: To assess the expression pattern of X-linked inhibitor of apoptosis protein (XIAP), a cellular stress sensor, and delineate the associated changes in the tumor immune microenvironment (TiME) for prognostic value and new therapeutic targets
Externí odkaz:
https://doaj.org/article/439d44debf2b4643bb138313adffcb0b