Zobrazeno 1 - 10
of 147
pro vyhledávání: '"tumor glycolysis"'
Autor:
Danxia Qiu, Yangcheng He, Yuyi Feng, Minhua Lin, Zekai Lin, Zhiyi Zhang, Ying Xiong, Zhiwen Hu, Suihong Ma, Hai Jin, Jianhua Liu
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
The tumor microenvironment is increasingly acknowledged as a critical contributor to cancer progression, mediating genetic and epigenetic alterations. Beyond diverse cellular interactions from the microenvironment, physicochemical factors such as tum
Externí odkaz:
https://doaj.org/article/836a86fc770f4c6ebb9f73d427326280
Publikováno v:
Molecular Therapy: Oncolytics, Vol 31, Iss , Pp 100750- (2023)
Aerobic glycolysis is a hallmark property of cancer metabolism. Enolase is a glycolytic enzyme that catalyzes the conversion of 2-phosphoglycerate into phosphoenolpyruvate. In mammals, enolases exist in three isoforms, encoded by the genes ENO1, ENO2
Externí odkaz:
https://doaj.org/article/c7ff07d6b025486c97653f14157d05a6
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-12 (2022)
Abstract Background Tumor glycolysis is a critical event for tumor progression. Docetaxel is widely used as a first-line drug for chemotherapy and shown to have a survival advantage. However, the role of docetaxel in tumor glycolysis remained poorly
Externí odkaz:
https://doaj.org/article/0c77704b72c54617bb34ee41c4682345
Autor:
Ashley Schreier, Roberta Zappasodi, Inna Serganova, Kristy A. Brown, Sandra Demaria, Eleni Andreopoulou
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
Triple negative breast cancer (TNBC) is an aggressive disease that is difficult to treat and portends a poor prognosis in many patients. Recent efforts to implement immune checkpoint inhibitors into the treatment landscape of TNBC have led to improve
Externí odkaz:
https://doaj.org/article/e216546cd79e4e67a3b6d08b973554a0
Publikováno v:
Advances in Cancer Biology - Metastasis, Vol 5, Iss , Pp 100058- (2022)
Lactate, the main product of tumor glycolysis is considered one of the most crucial metabolites in the tumor microenvironment. The reprogrammed cancer cell metabolism is closely associated with the enhanced rate of tumor glycolysis leading to excess
Externí odkaz:
https://doaj.org/article/1c02c172c3e249b5a79ad4a9f9566164
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 1, Pp 58-67 (2021)
Despite the anti-proliferative and survival benefits from tumor treating fields (TTFields) in human glioblastoma (hGBM), little is known about the effects of this form of alternating electric fields therapy on the aberrant glycolysis of hGBM. [18F]FD
Externí odkaz:
https://doaj.org/article/78fbf65abcd14fca8529674bee118405
Autor:
Ioana-Ecaterina Pralea, Alina-Maria Petrache, Adrian Bogdan Tigu, Diana Gulei, Radu-Cristian Moldovan, Maria Ilieș, Raul Nicoară, Simona-Codruța Hegheș, Alina Uifălean, Cristina-Adela Iuga
Publikováno v:
Pharmaceuticals, Vol 15, Iss 7, p 808 (2022)
The full understanding of the complex nature of cancer still faces many challenges, as cancers arise not as a result of a single target disruption but rather involving successive genetic and epigenetic alterations leading to multiple altered metaboli
Externí odkaz:
https://doaj.org/article/a478f90a72f94eb0af40e00b4702d428
Autor:
Feng Xu, Huan Xu, Zixiong Li, Yuanyuan Huang, Xiaoling Huang, Yangyi Li, Xiaohe Zheng, Yongsong Chen, Ling Lin
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
While increased glycolysis has been identified as a cancer marker and attracted much attention in thyroid cancer (THCA), the prognostic role of it remains to be further elucidated. Here we aimed to determine a specific glycolysis-associated risk mode
Externí odkaz:
https://doaj.org/article/55f294e7eb2b4de692a644d049855576
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Akademický článek
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