Zobrazeno 1 - 10
of 146
pro vyhledávání: '"tumor exosomes"'
Autor:
Xiang Li, Shaomin Wang, Wei Mu, Jennifer Barry, Anna Han, Richard L. Carpenter, Bing-Hua Jiang, Stephen C. Peiper, Mỹ G. Mahoney, Andrew E. Aplin, Hong Ren, Jun He
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-19 (2022)
Abstract Background Cancer cells have an imbalance in oxidation-reduction (redox) homeostasis. Understanding the precise mechanisms and the impact of the altered redox microenvironment on the immunologic reaction to tumors is limited. Methods We isol
Externí odkaz:
https://doaj.org/article/54c8d14e4d4c415ea3b2296caa6d7c60
Akademický článek
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Autor:
Yulia S. Korneva, Roman V. Ukrainets
Publikováno v:
Современная онкология, Vol 21, Iss 4, Pp 6-9 (2020)
The article is devoted to premetastatic niche as a complex term, including stromal cells, vessels, extracellular matrix and their changes during interaction with the primary tumor. On example of different malignant tumors authors describe as primary
Externí odkaz:
https://doaj.org/article/726b5bb290fb4cb2821bb88dee572a31
Autor:
Changguo Gong, Xiao Zhang, Min Shi, Feng Li, Shuang Wang, Yan Wang, Yugang Wang, Wei Wei, Guanghui Ma
Publikováno v:
Advanced Science, Vol 8, Iss 10, Pp n/a-n/a (2021)
Abstract As membrane‐bound extracellular vesicles, exosomes have targeting ability for specific cell types, and the cellular environment strongly impacts their content and uptake efficiency. Inspired by these natural properties, the impacts of vari
Externí odkaz:
https://doaj.org/article/966078ac3703478a960b38234958fe99
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Tumor-derived extracellular vesicles (TEVs) are important regulators of the immune response in cancer; however, most research so far has been carried out using cell culture systems. Immune-competent murine tumor models currently provide the best plat
Externí odkaz:
https://doaj.org/article/4fe81be5e5394101b8d0c16b192363fc
Autor:
Yoon‐Tae Kang, Thomas Hadlock, Ting‐Wen Lo, Emma Purcell, Anusha Mutukuri, Shamileh Fouladdel, Monica De Silva Raguera, Heather Fairbairn, Vasudha Murlidhar, Alison Durham, Scott A. McLean, Sunitha Nagrath
Publikováno v:
Advanced Science, Vol 7, Iss 19, Pp n/a-n/a (2020)
Abstract Melanoma is among the most aggressive cancers, and its rate of incidence continues to grow. Early detection of melanoma has been hampered due to the lack of promising markers for testing. Recent advances in liquid biopsy have proposed noninv
Externí odkaz:
https://doaj.org/article/2478a8956f83442dae965a06016983c9
Autor:
Dirk Himbert, Philip Zeuschner, Hiresh Ayoubian, Joana Heinzelmann, Michael Stöckle, Kerstin Junker
Publikováno v:
Diagnostics, Vol 10, Iss 12, p 1034 (2020)
Extracellular vesicles (EVs) are secreted by healthy and tumor cells and are involved in cell–cell communication. Tumor-released EVs could represent a new class of biomarkers from liquid biopsies. The aim of this study was to identify tumor-specifi
Externí odkaz:
https://doaj.org/article/6134113a3bf842688aabe23e1279e7fc
Publikováno v:
Cells, Vol 9, Iss 2, p 319 (2020)
Tumor cell-derived extracellular vesicles (TEX) expressing tetraspanin Tspan8-alpha4/beta1 support angiogenesis. Tspan8-alpha6/beta4 facilitates lung premetastatic niche establishment. TEX-promoted target reprogramming is still being disputed, we exp
Externí odkaz:
https://doaj.org/article/92c9ddd219b04650840ec9bc3ce30560
Akademický článek
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Autor:
Isabel Britsch, Emily M. Ploeg, Xiurong Ke, Wijnand Helfrich, Hao Zhang, Douwe F. Samplonius, Schelto Kruijff, Mark A. J. M. Hendriks, Femke A Van der Zant
Publikováno v:
Cancer letters, 521, 109-118. ELSEVIER IRELAND LTD
Tumor-derived extracellular vesicles (EVs) carry potent immunosuppressive factors that affect the antitumor activities of immune cells. A significant part of the immunoinhibitory activity of EVs is attributable to CD73, a GPI-anchored ecto-5′-nucle