Zobrazeno 1 - 10
of 3 630
pro vyhledávání: '"tumor associated macrophage"'
Autor:
Hiroaki Matsuzaki, Cheng Pan, Yoshihiro Komohara, Rin Yamada, Hiromu Yano, Yukio Fujiwara, Keitaro Kai, Akitake Mukasa
Publikováno v:
Immunological Medicine, Pp 1-9 (2024)
Glioblastoma (GBM) is the central nervous system tumor with the most aggressive behavior, and no definitive therapy has yet been found. The tumor microenvironment of GBM is immunosuppressive and is considered a ‘cold tumor’ with low lymphocytic i
Externí odkaz:
https://doaj.org/article/d0dd0c50717242e79bb05cd3a1956b70
Autor:
Zhao-Ru Dong, Meng-Ya Zhang, Ling-Xin Qu, Jie Zou, Yong-Heng Yang, Yun-Long Ma, Chun-Cheng Yang, Xue-Lei Cao, Li-Yuan Wang, Xiao-Lu Zhang, Tao Li
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-15 (2024)
Abstract Background Multiple studies have shown that tumor-associated macrophages (TAMs) promote cancer initiation and progression. However, the reprogramming of macrophages in the tumor microenvironment (TME) and the cross-talk between TAMs and mali
Externí odkaz:
https://doaj.org/article/1cce91b11b5f4a4ea687952e33ce33cc
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-18 (2024)
Abstract Background Treatment of gliomas, the most prevalent primary malignant neoplasm of the central nervous system, is challenging. Arachidonate 5-lipoxygenase activating protein (ALOX5AP) is crucial for converting arachidonic acid into leukotrien
Externí odkaz:
https://doaj.org/article/ffa96d91d98f44498de6d33e58f1c9a3
Autor:
Weihong Chen, Mingyuan Chen, Lingju Hong, Abudukeremu Xiahenazi, Maotuan Huang, Nanhong Tang, Xinyue Yang, Feifei She, Yanling Chen
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-19 (2024)
Abstract Background The predominant immune cells in solid tumors are M2-like tumor-associated macrophages (M2-like TAMs), which significantly impact the promotion of epithelial-mesenchymal transition (EMT) in tumors, enhancing stemness and facilitati
Externí odkaz:
https://doaj.org/article/87f4d6cbd0214a18ac9955a8afb48606
Autor:
Meysam Motevasseli, Maryam Darvishi, Alireza Khoshnevisan, Mehdi Zeinalizadeh, Hiva Saffar, Shiva Bayat, Ali Najafi, Mohammad Javad Abbaspour, Ali Mamivand, Susan B. Olson, Mina Tabrizi
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-20 (2024)
Abstract Tumor-associated macrophages (TAMs) residing in the tumor microenvironment (TME) are characterized by their pivotal roles in tumor progression, antitumor immunity, and TME remodeling. However, a thorough comparative characterization of tumor
Externí odkaz:
https://doaj.org/article/1b2d84d07e814d528d1858042d4dd751
Autor:
Shaoyuan Zhang, Jianmin Gu, Wenhan Wang, Linyi Sun, Tian Jiang, Xinyu Yang, Jun Yin, Miao Lin, Dong Lin, Hao Wang, Lijie Tan
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Esophageal cancer is common worldwide, with ESCC being the most frequent tumor in East Asia. Tumor-associated macrophages are an important component of the ESCC microenvironment. SUMOylation is a post-translational modification of proteins,
Externí odkaz:
https://doaj.org/article/d2485f0465a34fccac17815b8e368fb6
Autor:
Yi‐Cheng Pan, Pei‐Yi Chu, Ching‐Chan Lin, Ching‐Yun Hsieh, Wei‐Yu Hsu, Lie‐Fen Shyur, Juan‐Cheng Yang, Wei‐Chao Chang, Yang‐Chang Wu
Publikováno v:
Molecular Oncology, Vol 18, Iss 8, Pp 1866-1884 (2024)
Bladder cancer poses a significant challenge to chemotherapy due to its resistance to cisplatin, especially at advanced stages. Understanding the mechanisms behind cisplatin resistance is crucial for improving cancer therapy. The enzyme glutathione S
Externí odkaz:
https://doaj.org/article/2b592489dea7445fbc623aa501dcb1dd
Publikováno v:
Shanghai Jiaotong Daxue xuebao. Yixue ban, Vol 44, Iss 7, Pp 830-838 (2024)
Tumor microenvironment (TME) is a complex cellular environment where tumor cells reside, along with various types of cells and extracellular components surrounding the tumor cells. Immune cells are key components of TME, including tumor-associated ma
Externí odkaz:
https://doaj.org/article/8b7c54b7f8e0499f8c03c4638141bdbf
Autor:
Gaku Ota, Ryo Inoue, Akira Saito, Yoshihiko Kono, Joji Kitayama, Naohiro Sata, Hisanaga Horie
Publikováno v:
Journal of the Anus, Rectum and Colon, Vol 8, Iss 3, Pp 235-245 (2024)
Objectives: The aim of this study was to identify the microbiota whose decrease in tumor area was associated with the metastatic process of distal colorectal cancer (CRC). Methods: Twenty-eight consecutive patients with distal CRC undergoing surgical
Externí odkaz:
https://doaj.org/article/6579df500bec4ebb941bec44db6959d3
Publikováno v:
Thoracic Cancer, Vol 15, Iss 21, Pp 1626-1637 (2024)
Abstract Background Improving immunotherapy efficacy for EGFR‐negative lung adenocarcinoma (LUAD) patients remains a critical challenge, and the therapeutic effect of immunotherapy is largely determined by the tumor microenvironment (TME). Tumor‐
Externí odkaz:
https://doaj.org/article/9262f090e6164a6b966e3256c883ae26