Zobrazeno 1 - 7
of 7
pro vyhledávání: '"tumor angiogenesi"'
Autor:
Roxana E. Oberkersch, Giovanna Pontarin, Matteo Astone, Marianna Spizzotin, Liaisan Arslanbaeva, Giovanni Tosi, Emiliano Panieri, Sara Ricciardi, Maria Francesca Allega, Alessia Brossa, Paolo Grumati, Benedetta Bussolati, Stefano Biffo, Saverio Tardito, Massimo M. Santoro
Angiogenesis, the active formation of new blood vessels from pre-existing ones, is a complex and demanding biological process that plays an important role in physiological as well as pathological settings. Recent evidence supports cell metabolism as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef01762b0a666724967e4c91e48d5931
https://hdl.handle.net/11588/899906
https://hdl.handle.net/11588/899906
Autor:
Lavinia Raimondi, Alessia Gallo, Nicola Cuscino, Angela De Luca, Viviana Costa, Valeria Carina, Daniele Bellavia, Matteo Bulati, Riccardo Alessandro, Milena Fini, Pier Giulio Conaldi, Gianluca Giavaresi
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 705
International Journal of Molecular Sciences, Vol 23, Iss 705, p 705 (2022)
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 705
International Journal of Molecular Sciences, Vol 23, Iss 705, p 705 (2022)
Osteosarcoma (OS) is the most common primary bone tumor mainly occurring in young adults and derived from primitive bone-forming mesenchyme. OS develops in an intricate tumor microenvironment (TME) where cellular function regulated by microRNAs (miRN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e1c9bc5924d17a6cdf3c9daecbbc699
https://doi.org/10.3390/ijms23020705
https://doi.org/10.3390/ijms23020705
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030430924
There are many reasons to try to achieve a good grasp of the distribution of oxygen in the tumor microenvironment. The lack of oxygen - hypoxia - is a main actor in the evolution of tumors and in their growth and appears to be just as important in tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9445778d03c851d5f34b7af2bd3c526
http://hdl.handle.net/11368/2969015
http://hdl.handle.net/11368/2969015
Autor:
M Kazemi, A Carrer, S Moimas, L Zandonà, R Bussani, B Casagranda, S Palmisano, P Prelazzi, M Giacca, L Zentilin, N De Manzini, S Zacchigna
Publikováno v:
Cancer Gene Therapy. 23:125-132
Tumor angiogenesis depends on the vascular endothelial growth factor (VEGF), which exists in multiple splicing isoforms, including the most abundant VEGF165 and VEGF121. We have previously shown that the differential capacity of these two VEGF isofor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05193115d9825a404d8da6d247ca31d3
https://doi.org/10.1038/cgt.2016.12
https://doi.org/10.1038/cgt.2016.12
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
One of many important features of the tumour microenvironment is that it is a place of active Darwinian selection where different tumour clones become adapted to the variety of ecological niches that make up the microenvironment. These evolutionary p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f68dd183871037ea745c75bc41d39ac
http://hdl.handle.net/11368/2947881
http://hdl.handle.net/11368/2947881
Autor:
Raffaella Giavazzi, Robert Fruscio, Sara Figini, Maria Rosa Bani, Alessia Anastasia, Antonietta Silini, Monica Lupi, Carmen Ghilardi
Publikováno v:
Oncotarget
Europe PubMed Central
Europe PubMed Central
Proteases contribute to cancer in many ways, including tumor vascularization and metastasis, and their pharmacological inhibition is a potential anticancer strategy. We report that human endothelial cells (EC) express the trypsinogen 4 isoform of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13f63992173f8d75a2efa37d79b1a032
https://pubmed.ncbi.nlm.nih.gov/26318044
https://pubmed.ncbi.nlm.nih.gov/26318044
Autor:
Guido Bocci, Silvia Salerno, Ettore Novellino, Sabrina Taliani, Sandro Cosconati, Stefania Sartini, Concettina La Motta, Lisa Dalla Via, Paola Orlandi, Federico Da Settimo, Anna Fioravanti, Anna Maria Marini, Pilar D'Ocon, Ornella Gia, Francesca Simorini, Aída Nelly García-Argáez, G. Fornaciari
Vascular Endothelial Growth Factor (VEGF) pathway has emerged as one of the most important positive modulators of Angiogenesis, a central process implicated in tumour growth and metastatic dissemination. This led to the design and development of anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f9fea5b0bfe3a0329bd4a58a98610f
http://hdl.handle.net/11591/195244
http://hdl.handle.net/11591/195244