Zobrazeno 1 - 10
of 4 026
pro vyhledávání: '"tumor–stroma"'
Autor:
Serena Mancarella, Isabella Gigante, Elena Pizzuto, Grazia Serino, Alberta Terzi, Francesco Dituri, Eugenio Maiorano, Leonardo Vincenti, Mario De Bellis, Francesco Ardito, Diego F. Calvisi, Gianluigi Giannelli
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-15 (2024)
Abstract Background Cancer-associated fibroblasts (CAFs), mainly responsible for the desmoplastic reaction hallmark of intrahepatic Cholangiocarcinoma (iCCA), likely have a role in tumor aggressiveness and resistance to therapy, although the molecula
Externí odkaz:
https://doaj.org/article/f7201f2a93ed4fb2bd5f4cc907746a8b
Immunomodulatory role of tumor microenvironment on oncological outcomes in advanced laryngeal cancer
Autor:
Anna Rzepakowska, Joanna Olędzka, Piotr Daniel, Marta Mękarska, Michał Żurek, Karol Kulbaka, Łukasz Fus
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background The study evaluated the prognostic impact of the immune microenvironment in LSCC with markers of major immune cells to identify the key determinants of short-term disease-free survival (ST DFS) and reveal factors related to diseas
Externí odkaz:
https://doaj.org/article/b523a5dc63db4a539b5f2018789ead10
Autor:
Gamze AKBAS, Pelin BAGCI
Publikováno v:
Türk Patoloji Dergisi, Vol 40, Iss 3, Pp 181-189 (2024)
Objective: Pancreatic stellate cells (PSC) have been defined to be the key players in pancreatic fibrogenesis and carcinogenesis. They undergo myofibroblast-like differentiation, express α-smooth muscle actin (α-SMA), and play a crucial role in inj
Externí odkaz:
https://doaj.org/article/901ea4541e384215852bc7c70d1e0e40
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-12 (2024)
Abstract Background Currently, there is limited understanding regarding the clinical significance of the tumor-stroma ratio (TSR) in giant cell tumor of bone (GCTB). Hence, we aimed to investigate the distribution of TSR in GCTB and explore its corre
Externí odkaz:
https://doaj.org/article/cb7413226d4b468e9c55d7ba8c273384
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Chemotherapy and immunotherapy have shown no significant outcome for unresectable pancreatic ductal adenocarcinoma (PDAC). Multi-drug combination therapy has become a consensus in clinical trials to explore how to arouse anti-tumor immunity
Externí odkaz:
https://doaj.org/article/636570c8b9454344bfa1c84aa7444ff6
Autor:
Justus Kaufmann, Maximilian Haist, Ivan-Maximiliano Kur, Stefanie Zimmer, Jan Hagemann, Christoph Matthias, Stephan Grabbe, Heinz Schmidberger, Andreas Weigert, Arnulf Mayer
Publikováno v:
Translational Oncology, Vol 46, Iss , Pp 102019- (2024)
The growth pattern of oropharyngeal squamous cell carcinomas (OPSCC) varies from compact tumor cell aggregates to diffusely infiltrating tumor cell-clusters. The influence of the growth pattern on local tumor control and survival has been studied mai
Externí odkaz:
https://doaj.org/article/00464a0c31cb415aa53bf4a1c2be142f
Publikováno v:
FEBS Open Bio, Vol 14, Iss 4, Pp 675-686 (2024)
Collagen, the main component of the tumor microenvironment, plays a key role in the development of breast cancer (BCa); however, the specific changes in its spatial organization during tumor progression have not been definitively elucidated. The exis
Externí odkaz:
https://doaj.org/article/1a77e32f9cb14b83b4df6c2cc07ceec7
Publikováno v:
Oral Oncology Reports, Vol 10, Iss , Pp 100375- (2024)
Background: An important factor in the progression of tumours is the formation of blood vessels in the tumour stroma. When there is an upregulation of angiogenesis stimulators or a downregulation of angiogenesis inhibitors, the tumour may manifest it
Externí odkaz:
https://doaj.org/article/7c44a3d1fb434b65b3163c85c47b3c75
Publikováno v:
Cancer Medicine, Vol 13, Iss 12, Pp n/a-n/a (2024)
Abstract Introduction Therapy‐induced senescent cancer and stromal cells secrete cytokines and growth factors to promote tumor progression. Therefore, senescent cells may be novel targets for tumor treatment. Near‐infrared photoimmunotherapy (NIR
Externí odkaz:
https://doaj.org/article/71582fe5c90e42cca354aada49a0e70e
Publikováno v:
Oncology Reviews, Vol 18 (2024)
Emerging research has uncovered the significance of microbiota in carcinogenesis, with specific bacterial infectious agents linked to around 15% of malignant tumors. This review is focused on the resident kidney microbiome, its composition, and alter
Externí odkaz:
https://doaj.org/article/fd6dbcad7c3c41b4b961142d252aa921