Zobrazeno 1 - 10
of 8 892
pro vyhledávání: '"tumor‐targeting"'
Publikováno v:
Alexandria Engineering Journal, Vol 106, Iss , Pp 767-777 (2024)
The active ingredient in traditional Chinese medicine, silybin (SBN), is known to inhibit the proliferation of cancer cells and synergistically enhance the anticancer effects of the chemotherapy drug doxorubicin (DOX). However, the combination of SBN
Externí odkaz:
https://doaj.org/article/374b9706513e483bb8ae6514c0a5d65a
Autor:
Bowen Zeng, Lina Pian, Yanhong Liu, Shuangqing Wang, Nuoya Wang, Chao Liu, Hao Wu, Hongshuang Wan, Liqing Chen, Wei Huang, Zhonggao Gao, Xuezhe Yin, Mingji Jin
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Breast cancer therapy has significantly advanced by targeting the programmed cell death-ligand 1/programmed cell death-1 (PD-L1/PD-1) pathway. BMS-202 (a smallmolecule PD-L1 inhibitor) induces PD-L1 dimerization to block PD-1/PD-L1 interacti
Externí odkaz:
https://doaj.org/article/51f62b1377604f8bb41e12e6d76353bc
Autor:
Mengyi Yan, Xiayun Chen, Xiaotong Li, Qianqian Liu, Baixue Yu, Yi Cen, Wei Zhang, Yibin Liu, Xinxuan Li, Ying Chen, Tao Wang, Shiying Li
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 9, Pp 4118-4133 (2024)
The immunosuppressive phenotype of tumor cells extensively attenuates the immune activation effects of traditional treatments. In this work, a transferrin receptor (TfR) targeted immunostimulant (PTI) is fabricated for photodynamic immunotherapy agai
Externí odkaz:
https://doaj.org/article/e82264c1b8c34b5596ecc6997c5f01a8
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-24 (2024)
Abstract Adverse effects and multidrug resistance remain significant obstacles in conventional cancer therapy. Nanomedicines, with their intrinsic properties such as nano-sized dimensions and tunable surface characteristics, have the potential to mit
Externí odkaz:
https://doaj.org/article/05425797e8014bcca166e718a8b68891
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 9213-9226 (2024)
Wenlu Li,1,2,* Yaolin Gong,1,2,* Jing Zhang,1,2 Jiong Liu,1,2 Jiali Li,1,2 Shaozhi Fu,3 Wen Xiu Ren,1,2 Jian Shu1,2 1Department of Radiology, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, People’s Republic of Chi
Externí odkaz:
https://doaj.org/article/65308e157c3943328712950f790be859
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 8237-8251 (2024)
Xuefeng Hou,1– 4,* Qi Chen,1,* Ying Fang,5 Li Zhang,1 Shuoheng Huang,1 Minjie Xu,1 Yaning Ren,1 Zhansen Shi,1 Yan Wei,1 Lihua Li1– 4 1School of Pharmacy, Wannan Medical College, Wuhu, Anhui Province, People’s Republic of China; 2Anhui P
Externí odkaz:
https://doaj.org/article/fd363505dd494a5e8a687d1b6949ac39
Autor:
Yunyun Liu, Lihua Xiang, Yitong Li, Shen Zhang, Ying Zhang, Hui Shi, Hui Liu, Dou Du, Bangguo Zhou, Beibei Ye, Shaoyue Li, Haohao Yin, Huixiong Xu, Yifeng Zhang
Publikováno v:
Advanced Science, Vol 11, Iss 47, Pp n/a-n/a (2024)
Abstract Pyroptosis, an inflammatory cell death, has attracted great attention for potentiating a strong immune response against tumor cells. However, developing powerful pyroptosis inducers and then activating specific pyroptosis still remains chall
Externí odkaz:
https://doaj.org/article/3add5e2af68146e7bac2af6630e2ff8e
Autor:
Olaniyi Olarewaju, Franziska Held, Pamela Curtis, Cynthia Hess Kenny, Udo Maier, Tadas Panavas, Francois du Plessis
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 4, Pp 101378- (2024)
Due to the refractiveness of tumor tissues to adeno-associated virus (AAV) transduction, AAV vectors are poorly explored for cancer therapy delivery. Here, we aimed to engineer AAVs to target tumors by enabling the specific engagement of fibroblast a
Externí odkaz:
https://doaj.org/article/953471efcaa54a97877e67b01b80d553
Publikováno v:
Advanced Science, Vol 11, Iss 43, Pp n/a-n/a (2024)
Abstract Boron neutron capture therapy (BNCT) is a physiologically focused radiation therapy that relies on nuclear capture and fission processes. BNCT is regarded as one of the most promising treatments due to its excellent accuracy, short duration
Externí odkaz:
https://doaj.org/article/48d51b52761948ef8a5741d4d73c758f
Autor:
Yanan Cui, Seung Hun Park, Wesley R. Stiles, Atsushi Yamashita, Jason Dinh, Richard S. Kim, Yadong Zhang, Xiaoran Yin, Yoonji Baek, Haoran Wang, Kai Bao, Homan Kang, Hak Soo Choi
Publikováno v:
Small Science, Vol 4, Iss 11, Pp n/a-n/a (2024)
The use of ligand conjugation onto nanoparticle surfaces as an active targeting strategy has gained significant attention in the pursuit of improving tumor‐specific delivery and retention. However, the chemical conjugation of targeting moieties oft
Externí odkaz:
https://doaj.org/article/30e48aec8a9b4dcbae9176c512df6e55