Zobrazeno 1 - 10
of 3 742
pro vyhledávání: '"tumor‐initiating cells"'
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Thyroid cancer (TC) is the most common endocrine malignancy. Nowadays, undifferentiated thyroid cancers (UTCs) are still lethal, mostly due to the insurgence of therapy resistance and disease relapse. These events are believed to
Externí odkaz:
https://doaj.org/article/a5b84c9754e34fd5abe25fc05a072b92
Autor:
Kristian Pietras, Jonas Sjölund
Publikováno v:
Upsala Journal of Medical Sciences, Vol 129, Pp 1-5 (2024)
The complex interplay between genetically diverse tumor cells and their microenvironment significantly influences cancer progression and therapeutic responses. This review highlights recent findings on cellular plasticity and heterogeneity within the
Externí odkaz:
https://doaj.org/article/b15f6782c06b4255a8bbb5f0c9f2d1fc
Autor:
Qiaodan Deng, Jiankun Qiang, Cuicui Liu, Jiajun Ding, Juchuanli Tu, Xueyan He, Jie Xia, Xilei Peng, Siqin Li, Xian Chen, Wei Ma, Lu Zhang, Yi‐Zhou Jiang, Zhi‐Ming Shao, Ceshi Chen, Suling Liu, Jiahui Xu, Lixing Zhang
Publikováno v:
Advanced Science, Vol 11, Iss 29, Pp n/a-n/a (2024)
Abstract Breast tumor‐initiating cells (BTICs) of triple‐negative breast cancer (TNBC) tissues actively repair DNA and are resistant to treatments including chemotherapy, radiotherapy, and targeted therapy. Herein, it is found that a previously r
Externí odkaz:
https://doaj.org/article/1e3b009041f14a21a1f006ddc2dac957
Autor:
Zhi‐Jie Xiao, Si‐Qi Wang, Jun‐Jiang Chen, Yun Li, Yuchen Jiang, Vicky Pui‐Chi Tin, Jia Liu, Huiyi Hu, Maria Pik Wong, Yihang Pan, Judy Wai Ping Yam
Publikováno v:
Advanced Science, Vol 11, Iss 20, Pp n/a-n/a (2024)
Abstract Tumor‐initiating cells (TICs) resilience and an immunosuppressive microenvironment are aggressive oncogenic phenotypes that contribute to unsatisfactory long‐term outcomes in lung adenocarcinoma (LUAD) patients. The molecular mechanisms
Externí odkaz:
https://doaj.org/article/e915842cedec452eb9539396b6763cea
Autor:
Mingna Zhang, Yiqiao Fang, Xia Fu, Jiaye Liu, Yang Liu, Zhounan Zhu, Yinyun Ni, Menglin Yao, Qiuwei Pan, Wanlu Cao, Zhihui Li, Chunyan Dong
Publikováno v:
Cancer Medicine, Vol 12, Iss 17, Pp 18032-18049 (2023)
Abstract Background & Aims In liver cancer, leucine‐rich repeat‐containing G‐protein coupled receptor 5 (LGR5) compartment represents an important tumor‐initiating cell (TIC) population and served as a potential therapeutic target. Cancer‐a
Externí odkaz:
https://doaj.org/article/6dca15fe43bb4954acd3cd23f077e098
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Background: Triple-negative breast cancer (TNBC) is an aggressive subtype with the most unfavorable clinical outcomes, in part due to tumor heterogeneity, treatment resistance, and tumor relapse. The TNBC subtypes [basal-like 1 (BL1), basal-like 2 (B
Externí odkaz:
https://doaj.org/article/cc89dfb3e78e40f3886ef428e2aabab0
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 5, Pp 1105-1116 (2023)
Liver cancer (hepatocellular carcinoma) is a common cancer worldwide. It is an aggressive cancer, with high rates of tumor relapse and metastasis, high chemoresistance, and poor prognosis. Liver tumor-initiating cells (LTICs) are a distinctive subset
Externí odkaz:
https://doaj.org/article/128ded627e0a47b989cb8729172cbfb7
Autor:
Donatella Delle Cave, Silvia Buonaiuto, Bruno Sainz, Marco Fantuz, Maria Mangini, Alessandro Carrer, Annalisa Di Domenico, Tea Teresa Iavazzo, Gennaro Andolfi, Carme Cortina, Marta Sevillano, Christopher Heeschen, Vincenza Colonna, Marco Corona, Antonio Cucciardi, Martina Di Guida, Eduard Batlle, Annachiara De Luca, Enza Lonardo
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-20 (2022)
Abstract Background Tumor-initiating cells (TIC), also known as cancer stem cells, are considered a specific subpopulation of cells necessary for cancer initiation and metastasis; however, the mechanisms by which they acquire metastatic traits are no
Externí odkaz:
https://doaj.org/article/7a66930b577747c385f65ad7170426ec
Akademický článek
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Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 19, Iss 1 (2023)
A promising personal immunotherapy is autologous dendritic cells (DC) loaded ex vivo with autologous tumor antigens (ATA) derived from self-renewing autologous cancer cells. DC-ATA are suspended in granulocyte-macrophage colony stimulating factor at
Externí odkaz:
https://doaj.org/article/090d0e0ac7694bbe9ffdb397d49d9d3b