Zobrazeno 1 - 3
of 3
pro vyhledávání: '"tuberculosis and drug discovery"'
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 14, Pp 3235-3249 (2020)
Xolani H Makhoba,1 Claudio Viegas Jr,2 Rebamang A Mosa,1 Flávia PD Viegas,2 Ofentse J Pooe3 1Department of Biochemistry, Genetics and Microbiology, Division of Biochemistry, University of Pretoria, Hatfield, South Africa; 2Laboratory of Research in
Externí odkaz:
https://doaj.org/article/9817c2ef058d4755a509562a63eb20a4
Autor:
Vivek Srinivas, Rene A. Ruiz, Min Pan, Selva Rupa Christinal Immanuel, Eliza J.R. Peterson, Nitin S. Baliga
Here, we report the development of “DRonA” and “MLSynergy”, algorithms to perform rapid drug response assays and predict response of Mtb to novel drug combinations. Using a transcriptome signature for cell viability, DRonA accurately detects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bb9bb1858be77d544e83812d0bc4536
Publikováno v:
Drug Design, Development and Therapy
It is essential to acknowledge the efforts made thus far to manage or eliminate various disease burden faced by humankind. However, the rising global trends of the so-called incurable diseases continue to put pressure on Pharma industries and other d