Significance of extracellular vesicles in orchestration of immune responses in Mycobacterium tuberculosis infection

Autor: Shamila D. Alipoor, Daniel Elieh-Ali-Komi

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)

Mycobacterium tuberculosis (M.tb), the causative agent of Tuberculosis, is an intracellular bacterium well known for its ability to subvert host energy and metabolic pathways to maintain its intracellular survival. For this purpose, the bacteria util

Externí odkaz: https://doaj.org/article/0d136c0c84ab45cb95587696a5fb9e98

In Silico Development of Novel Benzofuran-1,3,4-Oxadiazoles as Lead Inhibitors of M. tuberculosis Polyketide Synthase 13

Autor: Ali Irfan, Shah Faisal, Ameer Fawad Zahoor, Razia Noreen, Sami A. Al-Hussain, Burak Tuzun, Rakshanda Javaid, Ahmed A. Elhenawy, Magdi E. A. Zaki, Sajjad Ahmad, Magda H. Abdellattif

Publikováno v: Pharmaceuticals, Vol 16, Iss 6, p 829 (2023)

Benzofuran and 1,3,4-oxadiazole are privileged and versatile heterocyclic pharmacophores which display a broad spectrum of biological and pharmacological therapeutic potential against a wide variety of diseases. This article reports in silico CADD (c

Externí odkaz: https://doaj.org/article/a7daf53a686440acbcc642c4ef7275aa

Classification of Tuberculosis Based on Lung X-Ray Image With Data Science Approach Using Convolutional Neural Network

Autor: Harahap, Mawaddah, Pasaribu, Alfeus P. S., Sinaga, Dedy Ridoly, Sipangkar, Romulus, Samuel, Samuel

Publikováno v: Sinkron : jurnal dan penelitian teknik informatika; Vol. 7 No. 4 (2022): Article Research: Volume 7 Number 4, October 2022; 2193-2197

Tuberculosis (TB) is a potentially serious infectious disease in the lungs, becoming 1 of 10 causes of death. In Indonesia, the disease is ranked third after India and China with 824,000 cases and 93,000 deaths per year, equivalent to 11 deaths per h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72f6c8c33dfca5cb2e7b96ea09afbe56
https://doi.org/10.33395/sinkron.v7i4.11711

Tuberculosis Molecular Bacterial Load Assay Reveals Early Delayed Bacterial Killing in Patients With Relapse

Autor: Ntinginya, Nyanda Elias, Bakuli, Abhishek, Mapamba, Daniel, Sabiiti, Wilber, Kibiki, Gibson, Minja, Lilian Tina, Kuchaka, Davis, Reither, Klaus, Phillips, Patrick Peter John, Boeree, Martin Johan, Gillespie, Stephen H, Hoelscher, Michael, Heinrich, Norbert, Pan African Consortium for the Evaluation of Antituberculosis Antibiotics (PanACEA) Consortium

Publikováno v: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, vol 76, iss 3
Clinical Infectious Diseases, 76, e990-e994
Clinical Infectious Diseases, 76, 3, pp. e990-e994

Funding: this work was supported by several funding agencies. The PanACEA MAMS study was funded by the European and Developing Countries Clinical Trials Partnership (EDCTP1); Grant No. IP.2007.32011.013, IP.2007.32011.012, and IP.2007.32011.011 as we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::556694a28a511dad628584ffd7dc1b28
https://doi.org/10.1093/cid/ciac445

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