Zobrazeno 1 - 4
of 4
pro vyhledávání: '"tubercidin analog"'
Autor:
Mustafa M. Aldfer, Ibrahim A. Alfayez, Hamza A. A. Elati, Nilanjana Gayen, Ehab Kotb Elmahallawy, Ana Milena Murillo, Sabrina Marsiccobetre, Serge Van Calenbergh, Ariel M. Silber, Harry P. de Koning
Publikováno v:
Molecules, Vol 27, Iss 22, p 8045 (2022)
Among the scarce validated drug targets against Chagas disease (CD), caused by Trypanosoma cruzi, the parasite’s nucleoside salvage system has recently attracted considerable attention. Although the trypanocidal activity of tubercidin (7-deazapurin
Externí odkaz:
https://doaj.org/article/dcdfd03943c144409fdee59cfd36c9d5
Autor:
Marzuq A. Ungogo, Mustafa M. Aldfer, Manal J. Natto, Hainan Zhuang, Robyn Chisholm, Katy Walsh, MarieClaire McGee, Kayhan Ilbeigi, Jamal Ibrahim Asseri, Richard J. S. Burchmore, Guy Caljon, Serge Van Calenbergh, Harry P. De Koning
Publikováno v:
International journal of molecular sciences
Ungogo, M, Aldfer, M M, Natto, M J, Zhuang, H, Chisholm, R, Walsh, K, McGee, M, Ilbeigi, K, Asseri, J I, Burchmore, R J S, Caljon, G, Van Calenbergh, S & De Koning, H P 2023, ' Cloning and characterization of Trypanosoma congolense and T. vivax nucleoside transporters reveal the potential of P1-type carriers for the discovery of broad-spectrum nucleoside-based therapeutics against Animal African trypanosomiasis ', International Journal of Molecular Sciences, vol. 24, no. 4, 3144, pp. 1-34 . https://doi.org/10.3390/ijms24043144
International Journal of Molecular Sciences
Volume 24
Issue 4
Pages: 3144
Ungogo, M, Aldfer, M M, Natto, M J, Zhuang, H, Chisholm, R, Walsh, K, McGee, M, Ilbeigi, K, Asseri, J I, Burchmore, R J S, Caljon, G, Van Calenbergh, S & De Koning, H P 2023, ' Cloning and characterization of Trypanosoma congolense and T. vivax nucleoside transporters reveal the potential of P1-type carriers for the discovery of broad-spectrum nucleoside-based therapeutics against Animal African trypanosomiasis ', International Journal of Molecular Sciences, vol. 24, no. 4, 3144, pp. 1-34 . https://doi.org/10.3390/ijms24043144
International Journal of Molecular Sciences
Volume 24
Issue 4
Pages: 3144
African Animal Trypanosomiasis (AAT), caused predominantly by Trypanosoma brucei brucei, T. vivax and T. congolense, is a fatal livestock disease throughout Sub-Saharan Africa. Treatment options are very limited and threatened by resistance. Tubercid
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