Zobrazeno 1 - 10
of 2 055
pro vyhledávání: '"trpm2"'
Publikováno v:
Cell Division, Vol 19, Iss 1, Pp 1-11 (2024)
Abstract Ovarian cancer (OC) becomes a fatal gynecologic malignant cancer in females worldwide. Target therapy is a promising therapeutical choice for patients with OC, and identifying biomarkers and exploring molecular mechanisms are necessary. In t
Externí odkaz:
https://doaj.org/article/66b8ee9df9784908969690d8952f5022
Publikováno v:
European Journal of Histochemistry, Vol 68, Iss 4 (2024)
The purpose of this study was to identify the role played by circEEF2 (has-circ-0048559) in prostate cancer (PCa) development and to determine the potential mechanism involved. circEEF2, miR-625-5p, and the transient receptor potential M2 channel pro
Externí odkaz:
https://doaj.org/article/b0f9a569a3aa414292db2864d9539603
Autor:
Zhen Chen, Karin A. Vallega, Vijay K. Boda, Zihan Quan, Dongsheng Wang, Songqing Fan, Qiming Wang, Suresh S. Ramalingam, Wei Li, Shi‐Yong Sun
Publikováno v:
Advanced Science, Vol 11, Iss 35, Pp n/a-n/a (2024)
Abstract There is an urgent need to fully understand the biology of third generation EGFR‐tyrosine kinase inhibitors (EGFR‐TKIs), particularly osimertinib, and to develop mechanism‐driven strategies to manage their acquired resistance. Transien
Externí odkaz:
https://doaj.org/article/724fd6fccbf0485f8840bc5a1b713315
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Ion channels play an important role in mediating pain through signal transduction, regulation, and control of responses, particularly in neuropathic pain. Transient receptor potential channel superfamily plays an important role in cation permeability
Externí odkaz:
https://doaj.org/article/3f0b81748962462ba74db7a6985996ba
Publikováno v:
Xin yixue, Vol 55, Iss 3, Pp 214-221 (2024)
Objective To investigate the role of transient receptor potential melatonin 2 （TRPM2） ion channels in microglia and astrocytes in temporal lobe epilepsy （TLE） -associated neuroinflammation. Methods Rats were randomly divided into the control
Externí odkaz:
https://doaj.org/article/b44a051ae5c84a6385aa64f7c06b5051
Autor:
Amelia M. Burch, Ami Haas, James E. Orfila, Erika Tiemeier, Cassidy De Anda Gamboa, Nicholas Chalmers, Nidia Quillinan, Paco S. Herson
Publikováno v:
Frontiers in Stroke, Vol 3 (2024)
Cardiac arrest-induced global cerebral ischemia (GCI) results in profound cognitive impairment in survivors. Our prior work demonstrated persistent disruption of long-term potentiation (LTP) in hippocampal CA1 neurons, correlating with learning and m
Externí odkaz:
https://doaj.org/article/72552ed10298439ca0b525e2e9a0ba77
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Transient receptor potential melastatin 2 (TRPM2) is a non-selective cation channel that exhibits Ca2+ permeability. The TRPM2 channel is expressed in various tissues and cells and can be activated by multiple factors, including endogenous ligands, C
Externí odkaz:
https://doaj.org/article/57f018e6f24845449a68914a1d641586
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Identification of TRPM2 as a prognostic factor correlated with immune infiltration in ovarian cancer
Autor:
Wei Huang, Yuliang Wu, Ning Luo, Xueqian Shuai, Jing Guo, Chunyan Wang, Fanchun Yang, Li Liu, Shupeng Liu, Zhongping Cheng
Publikováno v:
Journal of Ovarian Research, Vol 16, Iss 1, Pp 1-14 (2023)
Abstract Introduction Ovarian cancer (OC) is one of the most common gynecologic malignant cancers with the current survival rate remaining low. TRPM2 has been reported as a survival predictor in various cancers but not in OC. The aim of this study is
Externí odkaz:
https://doaj.org/article/32d57b3fc4ac40beb60ad9587eed80f4