Zobrazeno 1 - 10
of 108
pro vyhledávání: '"trophoblast cell surface antigen 2"'
Publikováno v:
Chinese Journal of Lung Cancer, Vol 27, Iss 6, Pp 431-440 (2024)
Lung cancer is the most common malignant tumor and the second most common malignant tumor in terms of mortality in the world. Non-small cell lung cancer (NSCLC) is the most common pathological type of lung cancer. Currently, the first-line standard t
Externí odkaz:
https://doaj.org/article/24e4571a0d854bb09298304cb36521b3
Autor:
Jiani Wang, Zhongsheng Tong, Yinuo Tan, Yehui Shi, Yun Wu, Qing Zhou, Xiaoyan Xing, Xiaomei Chen, Fuming Qiu, Fei Ma
Publikováno v:
Cell Reports Medicine, Vol 5, Iss 9, Pp 101707- (2024)
Summary: This phase 1a study assesses ESG401 in patients with heavily pretreated locally advanced or metastatic solid tumors, focusing on metastatic breast cancer. Forty patients are enrolled: three experience dose-limiting toxicities, establishing t
Externí odkaz:
https://doaj.org/article/736f4c38ba8e4e2ca5a20e6083c652d7
Autor:
Qingyu Liao, Ruiming Zhang, Zuli Ou, Yan Ye, Qian Zeng, Yange Wang, Anqi Wang, Tingmei Chen, Chengsen Chai, Bianqin Guo
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 1, Pp 200762- (2024)
Circulating tumor cells (CTCs) are the seeds of distant metastases of malignant tumors and are associated with malignancy and risk of metastasis. However, tumor cells undergo epithelial-mesenchymal transition (EMT) during metastasis, leading to the e
Externí odkaz:
https://doaj.org/article/526a37691e4a43f68cfd4d31bd31f899
Autor:
Susanne Ghandili, Judith Dierlamm, Carsten Bokemeyer, Clara Marie von Bargen, Anne Menz, Sören Alexander Weidemann
Publikováno v:
Reports, Vol 7, Iss 2, p 37 (2024)
Although trophoblast cell surface antigen 2 (Trop2)-targeting drugs are already approved or under investigation in various solid tumors, the significance of Trop2 in lymphoma is unknown. Thus, our objective was to investigate the expression of Trop2
Externí odkaz:
https://doaj.org/article/0991490d20ac4aba85f35bb6a8076938
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Breast cancer is a heterogeneous disease characterized by distinct molecular subtypes, varied prognoses, and differential treatment responses. Understanding the molecular landscape and identifying therapeutic targets, such as trophoblast cell-surface
Externí odkaz:
https://doaj.org/article/403705f503a9479db850e34308874ec8
Autor:
Eisuke Tomiyama, Kazutoshi Fujita, Kosuke Nakano, Ken Kuwahara, Takafumi Minami, Taigo Kato, Koji Hatano, Atsunari Kawashima, Motohide Uemura, Tetsuya Takao, Hiroaki Fushimi, Kotoe Katayama, Seiya Imoto, Kazuhiro Yoshimura, Ryoichi Imamura, Hirotsugu Uemura, Norio Nonomura
Publikováno v:
Current Oncology, Vol 29, Iss 6, Pp 3911-3921 (2022)
Trophoblast cell surface antigen 2 (Trop-2, encoded by TACSTD2) is the target protein of sacituzumab govitecan, a novel antibody-drug conjugate for locally advanced or metastatic urothelial carcinoma. However, the expression status of Trop-2 in upper
Externí odkaz:
https://doaj.org/article/0a4fb7c503704d7199085de8222c3759
Autor:
LI Yujie, CHEN Hao
Publikováno v:
Zhongguo aizheng zazhi, Vol 32, Iss 3, Pp 268-273 (2022)
Pancreatic cancer is a malignant tumor with high incidence, rapid progression and low survival rate. It is in urgent need of new targets for precise treatment or improvement of prognosis. In recent years, it has been found that trophoblast cell surfa
Externí odkaz:
https://doaj.org/article/74ec0e600f9c43f6b8d7bf02be618c73
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