Zobrazeno 1 - 10
of 1 132
pro vyhledávání: '"trna-derived"'
Autor:
Kangfeng Jin, Jinran Wu, Junling Yang, Bairong Chen, Jing Xu, Hongyi Bao, Wei Zong, Cuihua Xie, Lin Chen, Feng Wang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Accumulating evidence has shown that tRNA-derived small RNAs (tsRNAs) play crucial roles in malignant tumor development. However, whether serum tsRNAs can act as potential biological markers for hepatocellular carcinoma (HCC) are still large
Externí odkaz:
https://doaj.org/article/32dc81d7dd2f468795682060cec642c4
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
The main function of transfer RNAs (tRNAs) is to carry amino acids into the ribosome and synthesize proteins under the guidance of messenger RNAs (mRNAs). In addition to this, it has been observed that tRNAs undergo precise cleavage at specific loci,
Externí odkaz:
https://doaj.org/article/065621d423cb407198c059c058946b4e
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Small non-coding RNAs (sncRNAs) derived from tRNAs are known as tRNA-derived small RNAs (tsRNAs). These tsRNAs are further categorized into tRNA-derived fragments (tRFs) and tRNA halves (tiRNAs), which play significant roles in the various m
Externí odkaz:
https://doaj.org/article/cd483803e6644c1185c532c623ce184c
Autor:
Matthew Uzelac, Weg M. Ongkeko
Publikováno v:
Translational Oncology, Vol 50, Iss , Pp 102135- (2024)
Roughly 54,000 individuals are diagnosed with head and neck cancers in the United States yearly. Transfer RNA-derived fragments (tRF) are the products of enzymatic cleavage of precursor tRNAs, and have been proposed for use as biomarkers of head and
Externí odkaz:
https://doaj.org/article/fc263f627d4c43868e373cc6c2e77e0b
Autor:
Mizhen Qiu, Fei Zeng, Yi Yan, Mu Xu, Xuexue Zhang, Zhijian Wang, Yutong Wang, Daying Zhang, Shibiao Chen
Publikováno v:
All Life, Vol 17, Iss 1 (2024)
The mechanism of pyroptosis in trigeminal neuralgia (TN) progression remains unclear. The discovery of tRNA-derived small RNAs (tsRNAs) in the mechanism of pyroptosis is a breakthrough. We aim to study whether tsRNA is involved in TN progression thro
Externí odkaz:
https://doaj.org/article/19c54869b08341edb39f7e56d29e97c5
Publikováno v:
Renal Failure, Vol 46, Iss 1 (2024)
The prevalence of diabetic kidney disease (DKD) is increasing annually. Damage to and loss of podocytes occur early in DKD. tRNA-derived fragments (tRFs), originating from tRNA precursors or mature tRNAs, are associated with various illnesses. In thi
Externí odkaz:
https://doaj.org/article/f655b11b9be84f9c8a436bbbf571c8ce
Autor:
Anna K. Goldkamp, Randy G. Atchison, Shollie M. Falkenberg, Rohana P. Dassanayake, John D. Neill, Eduardo Casas
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
Understanding the molecular mechanisms underlying immune response can allow informed decisions in drug or vaccine development, and aid in the identification of biomarkers to predict exposure or evaluate treatment efficacy. The objective of this study
Externí odkaz:
https://doaj.org/article/9157ae3599634964b14a592120682aea
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Hyperactive neutrophil extracellular traps (NETs) formation plays a crucial role in active severe systemic lupus erythematosus (SLE). However, what triggers the imbalance in dysregulated NETs formation in SLE is elusive. Transfer
Externí odkaz:
https://doaj.org/article/528b40b7311f4ce9b242e05fb3ac1401
Publikováno v:
Molecular and Cellular Probes, Vol 77, Iss , Pp 101975- (2024)
Recently, it has been discovered surprisingly that tRNA can be cleaved into specific small fragments under certain conditions. Most importantly, these tRNA-derived fragments (tRFs) participate in the regulation of gene expression, playing pivotal rol
Externí odkaz:
https://doaj.org/article/22600a5f458b4762b70cddced0a82900
Autor:
Xiaoling Ying, Wenyu Hu, Yapeng Huang, Yifan Lv, Ding Ji, Cong Chen, Baotong Yang, Chengcheng Zhang, Yaomin Liang, Haiqing Zhang, Mingrui Liu, Gang Yuan, Wenqi Wu, Weidong Ji
Publikováno v:
Advanced Science, Vol 11, Iss 31, Pp n/a-n/a (2024)
Abstract Emerging evidence indicates that transfer RNA (tRNA)‐derived small RNAs (tsRNAs), originated from tRNA with high abundance RNA modifications, play an important role in many complex physiological and pathological processes. However, the bio
Externí odkaz:
https://doaj.org/article/66e5088add8c44f69eb649cd89d35f5d