Detecting Gene-Environment Interaction for Maternal Exposures Using Case-Parent Trios Ascertained Through a Case With Non-Syndromic Orofacial Cleft

Autor: Wanying Zhang, Sowmya Venkataraghavan, Jacqueline B. Hetmanski, Elizabeth J. Leslie, Mary L. Marazita, Eleanor Feingold, Seth M. Weinberg, Ingo Ruczinski, Margaret A. Taub, Alan F. Scott, Debashree Ray, Terri H. Beaty

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Two large studies of case–parent trios ascertained through a proband with a non-syndromic orofacial cleft (OFC, which includes cleft lip and palate, cleft lip alone, or cleft palate alone) were used to test for possible gene–environment (G × E)

Externí odkaz: https://doaj.org/article/d2d845570c634b34a0d2c00920c5d220

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Case–Parent Trio Studies in Cleft Lip and Palate

Autor: Prashanth Cs, Mahamad Irfanulla Khan

Publikováno v: Global Medical Genetics

Cleft lip with or without cleft palate (CL/P) is one of the most common congenital malformations in humans involving various genetic and environmental risk factors. The prevalence of CL/P varies according to geographical location, ethnicity, race, ge

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http://europepmc.org/articles/PMC7772012

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The Genome of the Netherlands: design, and project goals

Autor: Elisabeth M. van Leeuwen, Jeroen F. J. Laros, Clara C. Elbers, Alexandros Kanterakis, Jessica van Setten, Cisca Wijmenga, Gonneke Willemsen, Vyacheslav Koval, Qibin Li, Sujie Cao, Jouke-Jan Hottenga, Jayne Y. Hehir-Kwa, Laurent C. Francioli, Kai Ye, Jeanine J. Houwing-Duistermaat, Morris A. Swertz, David van Enckevort, Sara L. Pulit, Karol Estrada, Hailiang Mai, Marian Beekman, Anton J. M. de Craen, Gert-Jan B. van Ommen, Ben A. Oostra, Androniki Menelaou, Hongzhi Cao, Martijn Dijkstra, Mathijs Kattenberg, Abdel Abdellaoui, Yingrui Li, Albert Hofman, Cornelia M. van Duijn, Martijn Vermaat, Eline Slagboom, Lennart C. Karssen, Johan T. den Dunnen, Freerk van Dijk, Fernanodo Rivadeneira, Dorret I. Boomsma, Ruoyan Chen, Patrick Deelen, Paul I.W. de Bakker, Peter de Knijff, Bruce H. R. Wolffenbuttel, Ning Li, Heorhiy Byelas, Victor Guryev, Yuanping Du, Pieter B. Neerincx, André G. Uitterlinden, Jun Wang, H. Eka D. Suchiman

Publikováno v: European Journal of Human Genetics, 22(2), 221-227
Boomsma, D I, Wijmenga, C, Slagboom, P E, Swertz, M, Karssen, L C, Abdellaoui, A, Ye, K, Guryev, V, Vermaat, M, Dijk, F, Francioli, L C, Hottenga, J J, Laros, J F J, Li, Q, Li., Y, Cao, H, Chen, R, Du, Y, Li, N, Cao, S, van Setten, J, Menelaou, A, Pulit, S L, Hehir-Kwa, J Y, Beekman, M, Elbers, C C, Byelas, H, de Craen, A J, Deelen, P, Dijkstra, M, den Dunnen, J T, de Knijff, P, Houwing-Duistermaat, J J, Koval, V, Estrada, K, Hofman, A, Kanterakis, A, van Enckevort, D, Mai, H, Kattenberg, V M, van Leeuwen, E M, Neerincx, P B T, Oostra, B, Rivadeneira, F, Suchiman, H E D, Uitterlinden, A G, Willemsen, G, Wolffenbuttel, B H, Wang, J, Bakker, P I W, van Ommen, G J & van Duijn, C M 2014, ' The Genome of the Netherlands: design, and project goals ', European Journal of Human Genetics, vol. 22, no. 2, pp. 221-227 . https://doi.org/10.1038/ejhg.2013.118
European Journal of Human Genetics
European Journal of Human Genetics, 22(2), 221-227. Nature Publishing Group
Boomsma, D I, Wijmenga, C, Slagboom, E P, Swertz, M A, Karssen, L C, Abdellaoui, A, Ye, K, Guryev, V, Vermaat, M, van Dijk, F, Francioli, L C, Hottenga, J J, Laros, J F J, Li, Q, Li, Y, Cao, H, Chen, R, Du, Y, Li, N, Cao, S, van Setten, J, Menelaou, A, Pulit, S L, Hehir-Kwa, J Y, Beekman, M, Elbers, C C, Byelas, H, de Craen, A J M, Deelen, P, Dijkstra, M, den Dunnen, J T, de Knijff, P, Houwing-Duistermaat, J, Koval, V, Estrada, K, Hofman, A, Kanterakis, A, van Enckevort, D, Mai, H, Kattenberg, M, van Leeuwen, E M, Neerincx, P B T, Oostra, B, Rivadeneira, F, Suchiman, E H D, Uitterlinden, A G, Willemsen, G, Wolffenbuttel, B H, Wang, J, de Bakker, P I W, van Ommen, G-J & van Duijn, C M 2014, ' The Genome of the Netherlands : design, and project goals ', European Journal of Human Genetics, vol. 22, pp. 221-227 . https://doi.org/10.1038/ejhg.2013.118
European journal of human genetics, 22(2), 221-227. Nature Publishing Group

Within the Netherlands a national network of biobanks has been established (Biobanking and Biomolecular Research Infrastructure-Netherlands (BBMRI-NL)) as a national node of the European BBMRI. One of the aims of BBMRI-NL is to enrich biobanks with d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d47a3ce5c64e19313f252097021146ee
https://pure.eur.nl/en/publications/f5aac076-e4f8-4f25-90ac-28fb141bff4a