Structural, computational, docking and biological studies of a triaminopyrimidine caspase-1 inhibitor

Autor: Grice, Kyle A. ^{⁎, a}, Varsbergs, Zoe M. ^a, Zhang, Yingjie ^a, Zingales, Sarah K. ^b, Johnson, Adam R. ^c, Sommer, Roger D. ^{d, e}, Karver, Caitlin E. ^{⁎, a}

Publikováno v: In Journal of Molecular Structure 15 December 2024 1318 Part 2

Traceless solid-phase synthesis of 2,4,6-chlorodiamino and triaminopyrimidines

Autor: Montebugnoli, Dario ^a, Bravo, Pierfrancesco ^{a, b}, Brenna, Elisabetta ^a, Mioskowski, Charles ^c, Panzeri, Walter ^b, Viani, Fiorenza ^b, Volonterio, Alessandro ^a, Wagner, Alain ^c, Zanda, Matteo ^{b, ∗}

Publikováno v: In Tetrahedron 2003 59(36):7147-7156

Crystal structure of 2,4-di-amino-6-oxo-3,6-di-hydro-pyrimidin-1-ium p-toluene-sulfonate

Autor: Sadasivam Sharmila Tagore, Krishnasamy Mamallan, V. Sethuraman, Sundaramoorthy Gomathi

Publikováno v: Acta Crystallographica Section E: Crystallographic Communications
Acta Crystallographica Section E: Crystallographic Communications, Vol 71, Iss 5, Pp 476-478 (2015)

In the crystal of the title salt, the 2,6-di­amino-4-oxo-1,3-di­hydro­pyrimidin-1-ium cations and the p-toluene­sulfonate anions are linked by a series of N—H⋯O hydrogen bonds, forming tunnel-like polymer chains propagating along [010].

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b7ea0d0b41ac2378c108edaa4ad8c5
https://pubmed.ncbi.nlm.nih.gov/25995859