Zobrazeno 1 - 10
of 86
pro vyhledávání: '"treatment response monitoring"'
Autor:
Ryan D. Gentzler, John Guittar, Akash Mitra, Wade T. Iams, Terri Driessen, Regina Schwind, Michelle M. Stein, Kristiyana Kaneva, Seung Won Hyun, Yan Liu, Adam J. Dugan, Cecile Rose T. Vibat, Chithra Sangli, Jonathan Freaney, Zachary Rivers, Josephine L. Feliciano, Christine Lo, Kate Sasser, Rotem Ben-Shachar, Halla Nimeiri, Jyoti D. Patel, Aadel A. Chaudhuri
Publikováno v:
Oncology and Therapy, Vol 12, Iss 3, Pp 509-524 (2024)
Abstract Introduction A dynamic molecular biomarker that can identify early efficacy of immune checkpoint inhibitor (ICI) therapy remains an unmet clinical need. Here we evaluate if a novel circulating tumor DNA (ctDNA) assay, xM, used for treatment
Externí odkaz:
https://doaj.org/article/e9866030c92c41cc8282109a54d5780e
Publikováno v:
Dubai Medical Journal, Vol 7, Iss 1 (2024)
Introduction: The beginning of exosome biosynthesis is marked by the emergence of the initial endosomes through the inward splitting of the plasma cell membrane. This process is facilitated through the endosomal categorization complex essential for t
Externí odkaz:
https://doaj.org/article/14a4f8f22058447788a126bd52671253
Autor:
Mayur Narkhede, Sarah Tomassetti, Madiha Iqbal, Antony Tin, Samuel Rivero-Hinojosa, Giby V. George, Hayley Widden, Ryan Benrud, Meenakshi Malhotra, Angel Rodriguez, Minetta C. Liu
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundA novel approach for molecular residual disease (MRD) detection and treatment monitoring is needed in diffuse large B-cell lymphoma (DLBCL) to identify patients with a poor prognosis. We performed a retrospective evaluation of commercial ct
Externí odkaz:
https://doaj.org/article/275a98f96b254ebebbd094c8182d6f4f
Autor:
Maya Kansara, Neeru Bhardwaj, Subotheni Thavaneswaran, Chang Xu, Jessica K. Lee, Lo‐Bin Chang, Russell W. Madison, Frank Lin, Eugene Hsu, Vipul Kumar Patel, Alexey Aleshin, Geoffrey R. Oxnard, John Simes, Halla Nimeiri, David M. Thomas
Publikováno v:
Molecular Oncology, Vol 17, Iss 2, Pp 298-311 (2023)
There is an urgent need to identify biomarkers of early response that can accurately predict the benefit of immune checkpoint inhibitors (ICI). Patients receiving durvalumab/tremelimumab had tumor samples sequenced before treatment (baseline) to iden
Externí odkaz:
https://doaj.org/article/c442c4094d7d4fbb9a169db3f368978a
Autor:
Paul van derLeest, Birgitta Hiddinga, Anneke Miedema, Maria L. Aguirre Azpurua, Naomi Rifaela, Arja terElst, Wim Timens, Harry J. M. Groen, Léon C. vanKempen, T. Jeroen N. Hiltermann, Ed Schuuring
Publikováno v:
Molecular Oncology, Vol 15, Iss 11, Pp 2910-2922 (2021)
Immunotherapy for metastasized non‐small‐cell lung cancer (NSCLC) can show long‐lasting clinical responses. Selection of patients based on programmed death‐ligand 1 (PD‐L1) expression shows limited predictive value for durable clinical bene
Externí odkaz:
https://doaj.org/article/3d6ef98ec808424e9bf8c4b94e7a4fc2
Autor:
Shaw-Wei D. Tsen, Luke E. Springer, Krishna Sharmah Gautam, Rui Tang, Kexian Liang, Gail Sudlow, Amir Kucharski, Christine T. N. Pham, Samuel Achilefu
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-13 (2021)
Abstract Background The development and optimization of therapies for rheumatoid arthritis (RA) is currently hindered by a lack of methods for early non-invasive monitoring of treatment response. Annexin A2, an inflammation-associated protein whose p
Externí odkaz:
https://doaj.org/article/c2748d36fa21481a93859a9c27874953
Autor:
Sheng-Wei Pan, Rehan R. Syed, Donald G. Catanzaro, Mei-Lin Ho, Chin-Chung Shu, Tsung-Yeh Tsai, Yen-Han Tseng, Jia-Yih Feng, Yuh-Min Chen, Wei-Juin Su, Antonino Catanzaro, Timothy C. Rodwell
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
ObjectivesHuman mitochondrial cell-free DNA (Mt-cfDNA) may serve as a useful biomarker for infectious processes. We investigated Mt-cfDNA dynamics in patients with pulmonary mycobacterial infections to determine if this novel biomarker could be used
Externí odkaz:
https://doaj.org/article/8fc2df74f932474c8054c6fa3b1cd66a
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