Zobrazeno 1 - 10
of 2 505
pro vyhledávání: '"transmembrane proteins"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Insects rely on odorant receptors (ORs) to detect and respond to volatile environmental cues, so the ORs are attracting increasing interest as potential targets for pest control. However, experimental analysis of their structures and functio
Externí odkaz:
https://doaj.org/article/4da645ee3e18485b8f5f747f95c8abea
Autor:
Adam Nelson, Nichole McMullen, Simon Gebremeskel, Roberto De Antueno, Duncan Mackenzie, Roy Duncan, Brent Johnston
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-17 (2024)
Abstract Background Metastatic breast cancer is a leading cause of cancer death in woman. Current treatment options are often associated with adverse side effects and poor outcomes, demonstrating the need for effective new treatments. Immunotherapies
Externí odkaz:
https://doaj.org/article/149fda54df0043feaa5581db68f00768
Autor:
Toshiyuki Murai
Publikováno v:
European Journal of Cell Biology, Vol 103, Iss 2, Pp 151413- (2024)
A wide variety of transmembrane signals are transduced by cell-surface receptors that activate intracellular signaling molecules. In particular, receptor clustering in the plasma membrane plays a critical role in these processes. Single-spanning or s
Externí odkaz:
https://doaj.org/article/43338a61391b416a968fa302bf07e964
Publikováno v:
BioChem, Vol 3, Iss 3, Pp 118-141 (2023)
Oncologic disease is a significant global health issue that causes thousands of deaths annually, and it has a significant impact on the quality of life of patients. Prostate cancer (PCa) is the second most diagnosed cancer and the fourth leading caus
Externí odkaz:
https://doaj.org/article/0e51868948544570bea93ffab110018f
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The nuclear pore complex (NPC) serves as a pivotal subcellular structure, acting as a gateway that orchestrates nucleocytoplasmic transport through a selectively permeable barrier. Nucleoporins (Nups), particularly those containing phenylalanine–gl
Externí odkaz:
https://doaj.org/article/e2d165ac76db4095986e3a98bba0a801
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 2602-2612 (2023)
The FtsQBL is an essential molecular complex sitting midway through bacterial divisome assembly. To visualize and understand its structure, and the consequences of its membrane anchorage, we produced a model of the E. coli complex using the deep-lear
Externí odkaz:
https://doaj.org/article/f86fa9d9863447ae968db1c3178d5ffe
Publikováno v:
Cellular & Molecular Biology Letters, Vol 27, Iss 1, Pp 1-14 (2022)
Abstract Fat storage-inducing transmembrane proteins (FITMs) were initially identified in 2007 as members of a conserved endoplasmic reticulum (ER) resident transmembrane protein gene family, and were found to be involved in lipid droplet (LD) format
Externí odkaz:
https://doaj.org/article/6f1f2633c11f46a692c09b5d79c752d2
Publikováno v:
Bioengineering, Vol 10, Iss 12, p 1351 (2023)
Numerous potential drug targets, including G-protein-coupled receptors and ion channel proteins, reside on the cell surface as multi-pass membrane proteins. Unfortunately, despite advances in engineering technologies, engineering biologics against mu
Externí odkaz:
https://doaj.org/article/aa5d9e78b6314eb3abca7811927c5f74
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
Low temperature stress significantly threatens crop productivity and economic sustainability. Plants counter this by deploying advanced molecular mechanisms to perceive and respond to cold stress. Transmembrane proteins initiate these responses, trig
Externí odkaz:
https://doaj.org/article/1bc78e4ffb8a4af6b557ec1ea1d89b3b
Autor:
Donald J. Tipper, Carol A. Harley
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
DNA replication, transcription, and translation in eukaryotic cells occur with decreasing but still high fidelity. In contrast, for the estimated 33% of the human proteome that is inserted as transmembrane (TM) proteins, insertion with a non-function
Externí odkaz:
https://doaj.org/article/6bedb0806d9c4b43855baa7c86043d0f