Zobrazeno 1 - 10
of 22 154
pro vyhledávání: '"transmembrane domain"'
Autor:
Bowen Jiang, Wei Zhang, Yu He, Zhen Wu, Mingshu Wang, Renyong Jia, Dekang Zhu, Mafeng Liu, Xinxin Zhao, Qiao Yang, Ying Wu, Shaqiu Zhang, Juan Huang, Xumin Ou, Di Sun, Anchun Cheng, Shun Chen
Publikováno v:
Poultry Science, Vol 103, Iss 6, Pp 103727- (2024)
ABSTRACT: Duck Tembusu virus (DTMUV) belongs to the Flaviviridae family and mainly infects ducks. Duck Tembusu virus genome encodes one polyprotein that undergoes cleavage to produce 10 proteins. Among these, NS4B, the largest transmembrane protein,
Externí odkaz:
https://doaj.org/article/583656cb485c40b8bac063091d1011ff
Publikováno v:
Biomolecules, Vol 14, Iss 3, p 375 (2024)
The plant hormone ethylene is a key regulator of plant growth, development, and stress adaptation. Many ethylene-related responses, such as abscission, seed germination, or ripening, are of great importance to global agriculture. Ethylene perception
Externí odkaz:
https://doaj.org/article/8889fac5be154087a2866311583dcebc
Autor:
Ayesha Khan, Richard Killick, Daniel Wirth, Dominique Hoogland, Kalina Hristova, Jakob P. Ulmschneider, Christopher R. King, Martin B. Ulmschneider
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 9, Iss 4, Pp n/a-n/a (2023)
Abstract Introduction Reducing brain levels of both soluble and insoluble forms of amyloid beta (Aβ) remains the primary goal of most therapies that target Alzheimer's disease (AD). However, no treatment has so far resulted in patient benefit, and c
Externí odkaz:
https://doaj.org/article/964ff61904ec4b6b91c1f1f545a124ba
Autor:
Xinyi Jiang, Le Chang, Ying Yan, Huimin Ji, Huizhen Sun, Yingzi Xiao, Shi Song, Kaihao Feng, Abudulimutailipu Nuermaimaiti, Lunan Wang
Publikováno v:
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 2184-2196 (2022)
Occult HBV infection (OBI) is a special infection status during Hepatitis B virus (HBV) infection. The underlying mechanism of its occurrence remains unclear. This study conducted sequencing analysis on 104 OBI plasma samples and 524 HBsAg positive s
Externí odkaz:
https://doaj.org/article/e7708719887a445d815920a3625fd5a5
Autor:
Paulus Wohlfart, Mounir Chehtane, Ernesto Luna, Riyaz Mehta, Marcus Korn, Anish Konkar, Uwe Schwahn, Stefan Petry, Norbert Tennagels, Maximilian Bielohuby
Publikováno v:
Frontiers in Drug Discovery, Vol 3 (2023)
Introduction: 9-PAHSA belongs to a class of endogenous mammalian bioactive lipids, fatty acid esters of hydroxy fatty acids (FAHFA), that are present in circulation at nanomolar concentrations in mice and humans. Published preclinical data suggest be
Externí odkaz:
https://doaj.org/article/e992712713fd4d68a74d740cdfc2d6a2
Autor:
Jean-Philippe Defour, Emilie Leroy, Sharmila Dass, Thomas Balligand, Gabriel Levy, Ian C Brett, Nicolas Papadopoulos, Céline Mouton, Lidvine Genet, Christian Pecquet, Judith Staerk, Steven O Smith, Stefan N Constantinescu
Publikováno v:
eLife, Vol 12 (2023)
Dimerization of the thrombopoietin receptor (TpoR) is necessary for receptor activation and downstream signaling through activated Janus kinase 2. We have shown previously that different orientations of the transmembrane (TM) helices within a recepto
Externí odkaz:
https://doaj.org/article/1ee10a5fc3a84ee99a24838835aabcec
Autor:
Anna Clara Miranda Moura, Isaac K. Asare, Mateo Fernandez Cruz, Antonio Javier Franco Aguado, Kaeleigh Dyan Tuck, Conner C. Campbell, Matthew W. Scheyer, Ikponwmosa Obaseki, Steve Alston, Andrea N. Kravats, Charles R. Sanders, Gary A. Lorigan, Indra D. Sahu
Publikováno v:
Membranes, Vol 14, Iss 2, p 45 (2024)
KCNE3 is a single-pass integral membrane protein that regulates numerous voltage-gated potassium channel functions such as KCNQ1. Previous solution NMR studies suggested a moderate degree of curved α-helical structure in the transmembrane domain (TM
Externí odkaz:
https://doaj.org/article/f8ac973c94f44591a95a61186b1b0d48
Publikováno v:
Biomolecules, Vol 13, Iss 12, p 1756 (2023)
Nrg1 (Neuregulin 1) type III, a susceptible gene of schizophrenia, exhibits a critical role in the central nervous system and is essential at each stage of Schwann’s cell development. Nrg1 type III comprises double-pass transmembrane domains, with
Externí odkaz:
https://doaj.org/article/bf053c288d2c435eb47c4328551f0cca