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pro vyhledávání: '"translation repression"'
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Akademický článek
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Publikováno v:
Neural Regeneration Research, Vol 15, Iss 1, Pp 47-52 (2020)
Over the past decades, tRNA was found to be a rich hub of RNA modifications such as 1-methyladenosine and 5-methycytosine modifications and others, holding more than half of all modifications occurring in RNA molecules. Moreover, tRNA was discovered
Externí odkaz:
https://doaj.org/article/5383e31a249b4688855976592a9076cb
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 2 (2021)
ABSTRACT When encountering oxidative stress, organisms selectively upregulate antioxidant genes and simultaneously suppress the translation of most other proteins. Eukaryotes employ multiple strategies to adjust translation at both the initiation and
Externí odkaz:
https://doaj.org/article/d6341e6ee0c5460eb551c71d9e29f41d
Autor:
Shaohong Chen, Guangxia Gao
Publikováno v:
Protein & Cell, Vol 8, Iss 10, Pp 750-761 (2017)
Abstract MicroRNAs (miRNAs) recruit the RNA-induced silencing complex (RISC) to repress the translation of target mRNAs. While the 5′ 7-methylguanosine cap of target mRNAs has been well known to be important for miRNA repression, the underlying mec
Externí odkaz:
https://doaj.org/article/5b16844a219a483293413b18d7d0984e
Autor:
Hélène Sanfaçon
Publikováno v:
Viruses, Vol 7, Iss 7, Pp 3392-3419 (2015)
Plant viruses recruit cellular translation factors not only to translate their viral RNAs but also to regulate their replication and potentiate their local and systemic movement. Because of the virus dependence on cellular translation factors, it is
Externí odkaz:
https://doaj.org/article/8d3c2665b22540d5b7666793fb077f36
Publikováno v:
Viruses, Vol 11, Iss 3, p 203 (2019)
Plants are persistently challenged by various phytopathogens. To protect themselves, plants have evolved multilayered surveillance against all pathogens. For intracellular parasitic viruses, plants have developed innate immunity, RNA silencing, trans
Externí odkaz:
https://doaj.org/article/9d55c4144dec42aba66708232237c945
Autor:
Yukina Yamauchi, Shingo Izawa
Publikováno v:
Frontiers in Microbiology, Vol 7 (2016)
Severe ethanol stress (>9% ethanol, v/v) as well as glucose deprivation rapidly induces a pronounced repression of overall protein synthesis in budding yeast Saccharomyces cerevisiae. Therefore, transcriptional activation in yeast cells under severe
Externí odkaz:
https://doaj.org/article/40f8c7a62ed444cb8696e11f88827e33
Nonsense‐mediated decay targets have multiple sequence‐related features that can inhibit translation
Autor:
Zhenguo Zhang, Li Zhou, Landian Hu, Yufei Zhu, Heng Xu, Yang Liu, Xianfen Chen, Xianfu Yi, Xiangyin Kong, Laurence D Hurst
Publikováno v:
Molecular Systems Biology, Vol 6, Iss 1, Pp 1-9 (2010)
Abstract Nonsense‐mediated mRNA decay (NMD) is a surveillance system that eliminates transcripts with premature termination codons. In this study, we show that mRNAs targeted by NMD are also suppressed at the translational level. The low translatio
Externí odkaz:
https://doaj.org/article/78deea994d15422eb71e4347c033e8f8
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 2 (2021)
Microbiology Spectrum
Microbiology Spectrum
When encountering oxidative stress, organisms selectively upregulate antioxidant genes and simultaneously suppress the translation of most other proteins. Eukaryotes employ multiple strategies to adjust translation at both the initiation and elongati