Zobrazeno 1 - 10
of 919
pro vyhledávání: '"transient receptor potential vanilloid 1"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Assessing localization of the transient receptor potential vanilloid-1 (TRPV1) in skin nerve fibers is crucial for understanding its role in peripheral neuropathy and pain. However, information on the specificity and sensitivity of TRPV1 ant
Externí odkaz:
https://doaj.org/article/ad3cd3e7373a4f8f9ced564c2cb09401
Publikováno v:
Journal of Pain Research, Vol Volume 17, Pp 3919-3932 (2024)
Yeeun Kim,1,2,* Min-A Je,1,2,* Myeongguk Jeong,1,2 Hyeokjin Kwon,1,2 Aelee Jang,3 Jungho Kim,1,2 Go-Eun Choi1,2 1Department of Clinical Laboratory Science, College of Health Sciences, Catholic University of Pusan, Busan, 46252, Republic of Ko
Externí odkaz:
https://doaj.org/article/8dca9e31faa64faf9eda5d0083b61e3c
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Chronic prostatitis/chronic pelvic pain syndrome is a prevalent condition affecting the male urinary system. The urinary dysfunction resulting from this disorder has a direct or indirect impact on the patient’s quality of life. Recent studies have
Externí odkaz:
https://doaj.org/article/67d317bbd4624de499679d19aabe4f2f
Autor:
Ádám István Horváth, Kata Bölcskei, Nikolett Szentes, Éva Borbély, Valéria Tékus, Bálint Botz, Kitti Rusznák, Anett Futácsi, Boldizsár Czéh, Péter Mátyus, Zsuzsanna Helyes
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionMonoiodoacetate (MIA)-induced osteoarthritis (OA) is the most commonly used rodent model for testing anti-OA drug candidates. Herein, we investigated the effects of our patented multitarget drug candidate SZV-1287 (3-(4,5-diphenyl-1,3-oxa
Externí odkaz:
https://doaj.org/article/7cfe2dd453ac46c1bfdceb5f12491f4b
Autor:
Liu-Hui Huang, Jiao Lyu, Sheng Chen, Ting-Yi Liang, Yu-Qing Rao, Ping Fei, Jing Li, Hai-Ying Jin, Pei-Quan Zhao
Publikováno v:
International Journal of Ophthalmology, Vol 17, Iss 3, Pp 420-434 (2024)
AIM: To explore whether autophagy functions as a cellular adaptation mechanism in lens epithelial cells (LECs) under hyperosmotic stress. METHODS: LECs were treated with hyperosmotic stress at the concentration of 270, 300, 400, 500, or 600 mOsm for
Externí odkaz:
https://doaj.org/article/8831cda2f0d3443081ecd76d0a99bf25
Transient receptor potential vanilloid-1 (TRPV1) channels act as suppressors of the growth of glioma
Publikováno v:
Brain Research Bulletin, Vol 211, Iss , Pp 110950- (2024)
The aim of this study was to investigate the expression and function of the transient receptor potential vanilloid 1 (TRPV1) in glioma. We found that the expression of TRPV1 mRNA and protein were upregulated in glioma compared with normal brain by qP
Externí odkaz:
https://doaj.org/article/c7b57133a308482d9ba1143db772a376
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Angiogenesis plays a key role in bone regeneration. The role of neurons of peripheral nerves involved in angiogenesis of bone defects needs to be explored. The transient receptor potential vanilloid 1 (TRPV1), a nociceptor of noxious stimuli, is expr
Externí odkaz:
https://doaj.org/article/d2fdf0ae7d2d4a76bf962e4fba4c5d33
Autor:
Chuanpeng Ren, Yanyun Ma, Yizhen Wang, Dan Luo, Yanhan Hong, Xinyuan Zhang, Hexiang Mei, Wei Liu
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 876 (2024)
Palmitoylethanolamide (PEA) exhibits multiple skincare functions such as anti-nociceptive and anti-inflammatory effects. However, its topical application is limited due to its difficulty in bypassing the stratum corneum barrier, relatively low bioava
Externí odkaz:
https://doaj.org/article/c6781c6a51d8435eb4a95057179bb605
Autor:
Keima Ito, Yoshihiro Kanemitsu, Takeshi Kamiya, Kensuke Fukumitsu, Norihisa Takeda, Tomoko Tajiri, Ryota Kurokawa, Hirono Nishiyama, Jennifer Yap, Satoshi Fukuda, Takehiro Uemura, Hirotsugu Ohkubo, Ken Maeno, Yutaka Ito, Tetsuya Oguri, Masaya Takemura, Akio Niimi
Publikováno v:
Allergology International, Vol 72, Iss 2, Pp 271-278 (2023)
Background: Although sensory nerve dysfunction is related to the pathology of severe uncontrolled asthma and functional gastrointestinal disorders (FGIDs), the impact of comorbid FGIDs on the pathophysiology of severe uncontrolled asthma remains poor
Externí odkaz:
https://doaj.org/article/4e70f357c0ca4a15b496c2c92959ce0f
Autor:
Ji-Hong Gong, Chang-Ming Zhang, Bo Wu, Zi-Xun Zhang, Zhong-Yan Zhou, Jia-Hui Zhu, Han Liu, Yi Rong, Qian Yin, Ya-Ting Chen, Rong Zheng, Guang-Zhong Yang, Xiao-Fei Yang, Su Chen
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Triterpenoid saponins from Stauntonia chinensis have been proven to be a potential candidate for inflammatory pain relief. Our pharmacological studies confirmed that the analgesic role of triterpenoid saponins from S. chinensis occurred via a particu
Externí odkaz:
https://doaj.org/article/ffdd413f9002456dae8fc050d371af76