Zobrazeno 1 - 10
of 4 849
pro vyhledávání: '"transforming growth factor beta 1"'
Autor:
Ingo Mrosewski, Valeriya Mantel, Matthias Urbank, Gundula Schulze-Tanzil, Christian Werner, Clemens Gögele, Maria Kokozidou, Thomas Bertsch
Publikováno v:
Heliyon, Vol 10, Iss 23, Pp e40826- (2024)
Background: Type 2 diabetes mellitus (T2DM) is marked by insulin resistance, low grade chronic inflammation, and endothelial dysfunction. Vitamin K2, especially menaquinone-7 (MK-7), might delay T2DM progression and alleviate its consequences. Hence,
Externí odkaz:
https://doaj.org/article/d2234eb46cc3476b8faf9735d3418699
Publikováno v:
Regenerative Therapy, Vol 26, Iss , Pp 407-414 (2024)
Introduction: Dentin matrix extracted protein (DMEP) is a mixture of proteins extracted from the organic matrix of a natural demineralized dentin matrix that is rich in a variety of growth factors. However, the effect of DMEP on cartilage regeneratio
Externí odkaz:
https://doaj.org/article/22aa8dcf1c514a5d8f04c5ef65778108
Autor:
Karl Martin Forbord, Ngoc Nguyen Lunde, Tatjana Bosnjak-Olsen, Harald Thidemann Johansen, Rigmor Solberg, Abbas Jafari
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Transforming growth factor-beta 1 (TGF-β1) is a critical regulator of skeletal homeostasis and has diverse effects on osteoblastogenesis. To date, the mechanisms behind the intriguing inhibitory effect of TGF-β1 on osteoblast maturation are not ful
Externí odkaz:
https://doaj.org/article/2ed4838aee4f4772985d37de03a1d9ac
Publikováno v:
Heliyon, Vol 10, Iss 16, Pp e36059- (2024)
Objective: To explore the mechanisms of the TGF-β1/Smad and NF-κB pathways in the effect of berberine (BBR) on colon cancer epithelial–mesenchymal transition (EMT) and their regulatory relationships with microRNAs (miRNAs). Methods: TGF-β1 was u
Externí odkaz:
https://doaj.org/article/c7654673d6b44de4bf3a7992d9d47d83
Autor:
Mrosewski, Ingo a, ⁎, Mantel, Valeriya a, b, Urbank, Matthias a, Schulze-Tanzil, Gundula c, Werner, Christian c, Gögele, Clemens c, Kokozidou, Maria c, 1, Bertsch, Thomas d, 1
Publikováno v:
In Heliyon 15 December 2024 10(23)
Publikováno v:
In Heliyon 30 August 2024 10(16)
Autor:
Minxiao Yi, Ye Yuan, Li Ma, Long Li, Wan Qin, Bili Wu, Bolong Zheng, Xin Liao, Guangyuan Hu, Bo Liu
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 1, Pp n/a-n/a (2024)
Abstract Background Radiotherapy is the main treatment modality for thoracic tumours, but it may induce pulmonary fibrosis. Currently, the pathogenesis of radiation‐induced pulmonary fibrosis (RIPF) is unclear, and effective treatments are lacking.
Externí odkaz:
https://doaj.org/article/7848d1aaa00b40bdb73b49237ccd1d35
Publikováno v:
Biomolecules & Biomedicine, Vol 23, Iss 6 (2023)
The ski-related novel gene (SnoN), encoded by the SKIL gene, has been shown to negatively regulated transforming growth factor-β1 (TGF-β1) signaling pathway. However, the roles of SnoN in hepatic stellate cell (HSC) activation and hepatic fibrosis
Externí odkaz:
https://doaj.org/article/350b8204f0f54ddebae8fc763fc7afa4
Autor:
Rehab Fawzy Abdel-Rahman, Hany M Fayed, Marwan A Mohamed, Alyaa F Hessin, Gihan F Asaad, Sahar S AbdelRahman, Abeer A Salama, Mahmoud S Arbid, Hanan A Ogaly
Publikováno v:
Journal of HerbMed Pharmacology, Vol 12, Iss 2, Pp 202-213 (2023)
Introduction: Liver tissue malfunction is a severe worldwide health concern that arises from various chronic liver conditions. The goal of this investigation was to look into the anti-fibrotic effect of apigenin (APG), an antioxidant found in various
Externí odkaz:
https://doaj.org/article/aa8f7c5f9ad44c889ed0a7ffc9976287
Autor:
Linfeng Wang, Shengcan Li, Han Xiao, Tao Zhang, Yuqian Liu, Jianzhong Hu, Daqi Xu, Hongbin Lu
Publikováno v:
Bone & Joint Research, Vol 12, Iss 3, Pp 219-230 (2023)
Aims: It has been established that mechanical stimulation benefits tendon-bone (T-B) healing, and macrophage phenotype can be regulated by mechanical cues; moreover, the interaction between macrophages and mesenchymal stem cells (MSCs) plays a fundam
Externí odkaz:
https://doaj.org/article/2e567006296f41abbfd69bac728c5c77