DEL-1, as an anti-neutrophil transepithelial migration molecule, inhibits airway neutrophilic inflammation in asthma.

Autor: Jia M; Department of Respiratory & Critical Care Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China., Fu H; Department of Respiratory & Critical Care Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China., Jiang X; Department of Respiratory & Critical Care Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China., Wang L; Department of Respiratory & Critical Care Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China., Xu J; Department of Respiratory & Critical Care Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China., Barnes PJ; Airway Disease Section, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, UK., Adcock IM; Airway Disease Section, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, UK., Liu Y; Department of Allergy, Pulmonary and Critical Care Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.; Shandong Key Laboratory of Infections Respiratory Disease, Medical Science and Technology Innovation Center, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China., He S; Department of Respiratory Medicine, Nanjing Red Cross Hospital, Nanjing, China., Zhang F; Department of Respiratory Medicine, Nanjing Red Cross Hospital, Nanjing, China., Yao L; Department of Respiratory & Critical Care Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China., Sun P; Department of Respiratory & Critical Care Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China., Yao X; Department of Respiratory & Critical Care Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Publikováno v: Allergy [Allergy] 2024 May; Vol. 79 (5), pp. 1180-1194. Date of Electronic Publication: 2023 Sep 08.

Plasma S1P Orchestrates the Reverse Transendothelial Migration of Aortic Intimal Myeloid Cells in Mice.

Autor: Polenz CK; Departments of Laboratory Medicine and Pathobiology (C.K.P., C.A.S., M.G.A., H.M.I., M.I.C.), University of Toronto, Canada.; Toronto General Hospital Research Institute, University Health Network, Canada (C.K.P., C.A.S., S.J.H., M.G.A., H.M.I., M.I.C.)., Scipione CA; Departments of Laboratory Medicine and Pathobiology (C.K.P., C.A.S., M.G.A., H.M.I., M.I.C.), University of Toronto, Canada.; Immunology (C.A.S., M.I.C.), University of Toronto, Canada.; Toronto General Hospital Research Institute, University Health Network, Canada (C.K.P., C.A.S., S.J.H., M.G.A., H.M.I., M.I.C.)., Hyduk SJ; Toronto General Hospital Research Institute, University Health Network, Canada (C.K.P., C.A.S., S.J.H., M.G.A., H.M.I., M.I.C.)., Althagafi MG; Departments of Laboratory Medicine and Pathobiology (C.K.P., C.A.S., M.G.A., H.M.I., M.I.C.), University of Toronto, Canada.; Toronto General Hospital Research Institute, University Health Network, Canada (C.K.P., C.A.S., S.J.H., M.G.A., H.M.I., M.I.C.)., Ibrahim HM; Departments of Laboratory Medicine and Pathobiology (C.K.P., C.A.S., M.G.A., H.M.I., M.I.C.), University of Toronto, Canada.; Toronto General Hospital Research Institute, University Health Network, Canada (C.K.P., C.A.S., S.J.H., M.G.A., H.M.I., M.I.C.)., Cybulsky MI; Departments of Laboratory Medicine and Pathobiology (C.K.P., C.A.S., M.G.A., H.M.I., M.I.C.), University of Toronto, Canada.; Immunology (C.A.S., M.I.C.), University of Toronto, Canada.; Toronto General Hospital Research Institute, University Health Network, Canada (C.K.P., C.A.S., S.J.H., M.G.A., H.M.I., M.I.C.).; Peter Munk Cardiac Centre, University Health Network, Toronto, Canada (M.I.C.).

Publikováno v: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2024 Apr; Vol. 44 (4), pp. 883-897. Date of Electronic Publication: 2024 Feb 08.

Epac activation reduces trans-endothelial migration of undifferentiated neuroblastoma cells and cellular differentiation with a CDK inhibitor further enhances Epac effect.

Autor: Inuwa RF; Department of Molecular Physiology and Cell Signalling, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, United Kingdom.; Faculty of Basic Medical Sciences, Department of Anatomy, College of Health Sciences, Bayero University, Kano, Nigeria., Moss D; Department of Molecular Physiology and Cell Signalling, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, United Kingdom., Quayle J; Department of Molecular Physiology and Cell Signalling, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, United Kingdom.; ALESS/ALESA Program, Center for Global Communication Strategies, Center for Global Education, University of Tokyo, Bunkyō, Japan., Swadi R; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, United Kingdom.; Institute for Health Research, Liverpool John Moores University, Liverpool, United Kingdom.

Publikováno v: PloS one [PLoS One] 2024 Nov 04; Vol. 19 (11), pp. e0304547. Date of Electronic Publication: 2024 Nov 04 (Print Publication: 2024).

RGS5 ⁺ lymphatic endothelial cells facilitate metastasis and acquired drug resistance of breast cancer through oxidative stress-sensing mechanism.

Autor: Qiu C; Department of Gastrointestine and Gland Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China., Tang C; Department of Gastrointestine and Gland Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China., Tang Y; Department of Gastrointestine and Gland Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China., Su K; Department of Gastrointestine and Gland Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China., Chai X; Department of Gastrointestine and Gland Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China., Zhan Z; Department of Gastrointestine and Gland Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China., Niu X; China Medical University Shenyang 110122, China; Experimental Center of BIOQGene, YuanDong International Academy of Life Sciences, 999077, Hong Kong, China. Electronic address: xniu@cmu.edu.cn., Li J; Department of Gastrointestine and Gland Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China. Electronic address: lijiehua01@sina.com.

Publikováno v: Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy [Drug Resist Updat] 2024 Nov; Vol. 77, pp. 101149. Date of Electronic Publication: 2024 Sep 06.

Endothelial Cell-Derived Extracellular Vesicles Promote Aberrant Neutrophil Trafficking and Subsequent Remote Lung Injury.

Autor: Zi SF; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China., Wu XJ; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China., Tang Y; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China., Liang YP; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China., Liu X; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China., Wang L; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China., Li SL; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China., Wu CD; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China., Xu JY; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China., Liu T; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China.; Department of Biochemistry and Molecular Biology, School of Medicine, Southeast University, Nanjing, 210009, China., Huang W; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China., Xie JF; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China., Liu L; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China., Chao J; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China.; Department of Physiology, School of Medicine, Southeast University, Nanjing, 210009, China., Qiu HB; Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China.

Publikováno v: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Oct; Vol. 11 (38), pp. e2400647. Date of Electronic Publication: 2024 Aug 09.