Zobrazeno 1 - 10
of 3 379
pro vyhledávání: '"transendothelial migration"'
Autor:
Yuying Ye, Mengting Lin, Guiyu Zhou, Weiyu Wang, Yinyin Yao, Yafei Su, Jianqiang Qi, Yanfang Zheng, Chunlian Zhong, Xi Chen, Mingqing Huang, Yusheng Lu
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Distant metastasis is a major cause of treatment failure in cancer patients and a key challenge to improving cancer care today. We hypothesized that enhancing anti-cancer immune response and inhibiting circulating tumor cells (CTCs) adhesion and tran
Externí odkaz:
https://doaj.org/article/3220316d945b42c1a367f0cc6c27f0de
Publikováno v:
Vascular Biology, Vol 5, Iss 1, Pp 1-13 (2023)
Intercellular adhesion molecules (ICAMs) are cell surface proteins that play a crucial role in the body’s immune response and inflammatory processes. ICAM1 and ICAM2 are two ICAM family members expressed on the surface of various cell types, includ
Externí odkaz:
https://doaj.org/article/4f15ddf2758745e1b658499b089f0162
Autor:
Arya Lekshmi Nair, Linda Groenendijk, Roos Overdevest, Tania M. Fowke, Rumaisha Annida, Orsola Mocellin, Helga E. de Vries, Nienke R. Wevers
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
The blood-brain barrier (BBB) is a highly selective barrier that ensures a homeostatic environment for the central nervous system (CNS). BBB dysfunction, inflammation, and immune cell infiltration are hallmarks of many CNS disorders, including multip
Externí odkaz:
https://doaj.org/article/6c036f95ae134d6ea4b6edc3bb440038
Autor:
Zhaolei Zou, Juan Fang, Wanting Ma, Junyi Guo, Zhongyan Shan, Da Ma, Qiannan Hu, Liling Wen, Zhi Wang
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Porphyromonas gingivalis is an important periodontal pathogen that can cause vascular injury and invade local tissues through the blood circulation, and its ability to evade leukocyte killing is critical to its distal colonization and surviv
Externí odkaz:
https://doaj.org/article/3455e4298b48490495e212d24df75996
Autor:
Aarren J. Mannion, Adam F. Odell, Syed Murtuza Baker, Laura C. Matthews, Pamela F. Jones, Graham P. Cook
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
CD146, also known as melanoma cell adhesion molecule (MCAM), is expressed in numerous cancers and has been implicated in the regulation of metastasis. We show that CD146 negatively regulates transendothelial migration (TEM) in breast cancer. This inh
Externí odkaz:
https://doaj.org/article/91b1642de92d457a99a0a2a29369437a
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16740 (2023)
Dysregulated B cell receptor-associated protein 31 (BAP31) plays a crucial role in tumor progression. This study aimed to investigate the functions and molecular mechanism of BAP31 on the miR-206/133b cluster in colorectal cancer (CRC). qPCR was cond
Externí odkaz:
https://doaj.org/article/126d78f1cf0143e0bca2afe1bf4925d2
Publikováno v:
Cancers, Vol 15, Iss 21, p 5160 (2023)
Chronic lymphocytic leukemia (CLL) is a B-cell malignancy whose progression largely depends on the lymph node and bone marrow microenvironment. Indeed, CLL cells actively proliferate in specific regions of these anatomical compartments, known as prol
Externí odkaz:
https://doaj.org/article/8542d53b03d743d1a57703bd3ce45a91
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Autor:
Svetlana N. Pleskova, Nikolay A. Bezrukov, Ekaterina N. Gorshkova, Sergey Z. Bobyk, Ekaterina V. Lazarenko
Publikováno v:
Cells, Vol 12, Iss 13, p 1806 (2023)
The dynamics of neutrophil transendothelial migration was investigated in a model of experimental septicopyemia. Scanning ion-conductance microscopy allowed us to determine changes in morphometric characteristics of endothelial cells during this proc
Externí odkaz:
https://doaj.org/article/3af7e407370f44bbb01169af8f2e3682
Autor:
Ricardo Huilcaman, Natalia Veliz-Olivos, Whitney Venturini, Alexandra Olate-Briones, Adriana V. Treuer, Claudio Valenzuela, Nelson Brown, Rodrigo Moore-Carrasco
Publikováno v:
Platelets, Vol 32, Iss 8, Pp 1113-1119 (2021)
Cardiovascular diseases (CVDs) remain leading causes of death worldwide. While platelet-mediated thrombus formation following the rupture of an atherosclerotic plaque is one of the key pathophysiologic events in CVDs, the role of platelets in previou
Externí odkaz:
https://doaj.org/article/bae285f9acae40369ee07ccffe52ca30