Zobrazeno 1 - 10
of 233
pro vyhledávání: '"transcriptomic sequencing"'
Publikováno v:
Zhongguo quanke yixue, Vol 27, Iss 29, Pp 3654-3663 (2024)
Background Hepatic macrophages play a vital role in the defense mechanisms and maintaining the internal environment stability of body, and are also major cellular components involved in liver injury and repair. Macrophages derived from hematopoietic
Externí odkaz:
https://doaj.org/article/966151a3fbd94205891bb345db758aac
Autor:
Min Deng, Woodvine O. Odhiambo, Min Qin, Thao Tam To, Gregory M. Brewer, Alexander R. Kheshvadjian, Carol Cheng, George W. Agak
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract A comprehensive understanding of the intricate cellular and molecular changes governing the complex interactions between cells within acne lesions is currently lacking. Herein, we analyzed early papules from six subjects with active acne vul
Externí odkaz:
https://doaj.org/article/351c9c971ce7421e93fde1ff3155d29f
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-15 (2024)
Abstract Cancer-associated fibroblasts (CAFs) are the major components of the tumor microenvironment and are related to tumor proliferation, metastasis, relapse, and drug resistance. With the development of sequencing technologies, single-cell RNA se
Externí odkaz:
https://doaj.org/article/ed8fa35fc52d4442bc0e386d16f8de54
Autor:
Qiuping Lin, Zhen Wang, Guohui Ding, Guang Li, Liqin Chen, Qingzhu Qiu, Sirui Song, Wei Liu, Xunwei Jiang, Min Huang, Libing Shen, Tingting Xiao, Lijian Xie
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundKawasaki disease (KD) is an acute systemic vasculitis that can lead to acquired heart disease in children mostly from in developed countries. The previous research showed that B cells in KD patients underwent a profound change in both the c
Externí odkaz:
https://doaj.org/article/449d2e10c8e04339925874fe4f33cd98
Publikováno v:
Brain Research Bulletin, Vol 217, Iss , Pp 111076- (2024)
In recent years, overwhelming evidence has emphasized the crucial role of inflammation in the pathogenesis of PD. However, the exact mechanisms by which inflammation damages dopaminergic neurons in PD are still unclear. Therefore, we generated a MPTP
Externí odkaz:
https://doaj.org/article/ea296ae5b81b41768feddaf2b044727b
Publikováno v:
陆军军医大学学报, Vol 46, Iss 10, Pp 1083-1091 (2024)
Objective To analyze the cellular senescence pathways and their associated genes with bioinformatic analysis by screening differentially expressed genes (DEGs) during embryonic kidney development with aid of transcriptomics in order to explore the re
Externí odkaz:
https://doaj.org/article/32739a7a4cc44428882af0e883ed1268
Autor:
Simeng Liu, Huijuan Wen, Fazhan Li, Xia Xue, Xiangdong Sun, Fuhao Li, Ruoyu Hu, Huayuan Xi, Francesco Boccellato, Thomas F Meyer, Yang Mi, Pengyuan Zheng
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Gastric intestinal metaplasia (GIM) is an essential precancerous lesion. Although the reversal of GIM is challenging, it potentially brings a state-to-art strategy for gastric cancer therapeutics (GC). The lack of the appropriate
Externí odkaz:
https://doaj.org/article/9ce16ff024ee41068d4718c07694e629
Autor:
Diana Omoke, Lucy Mackenzie Impoinvil, Dieunel Derilus, Stephen Okeyo, Helga Saizonou, Nicola Mulder, Nsa Dada, Audrey Lenhart, Luc Djogbénou, Eric Ochomo
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-23 (2024)
Abstract Background Effective vector control is key to malaria prevention. However, this is now compromised by increased insecticide resistance due to continued reliance on insecticide-based control interventions. In Kenya, we have observed heterogen
Externí odkaz:
https://doaj.org/article/6ca44f2a860541e5b4e7d0d2e2a3c605
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-20 (2024)
Abstract Objective Anesthetics have been linked to cognitive alterations, particularly in the elderly. The current research delineates how Fibroblast Growth Factor 2 (Fgf2) modulates tau protein phosphorylation, contributing to cognitive impairments
Externí odkaz:
https://doaj.org/article/b7ace567b7844f73b007bd84a544d32e