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pro vyhledávání: '"transcription factor TCF4"'
Autor:
Alex Sirp, Anastassia Shubina, Jürgen Tuvikene, Laura Tamberg, Carl Sander Kiir, Laura Kranich, Tõnis Timmusk
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Transcription factor 4 (TCF4) belongs to the class I basic helix–loop–helix family of transcription factors (also known as E-proteins) and is vital for the development of the nervous system. Aberrations in the TCF4 gene are associated with severa
Externí odkaz:
https://doaj.org/article/9b778188fd544b8fa16f929f6f9ccfae
Akademický článek
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Publikováno v:
The Journal of Biological Chemistry
Journal of Biological Chemistry
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ORCID
Microsoft Academic Graph
PubMed Central
Journal of Biological Chemistry
UnpayWall
ORCID
Microsoft Academic Graph
PubMed Central
Transcription factor 4 (TCF4) is a basic helix-loop-helix transcription factor essential for neurocognitive development. The aberrations in TCF4 are associated with neurodevelopmental disorders including schizophrenia, intellectual disability, and Pi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::571fb9a500003d0acbefc612aacd700e
https://pubmed.ncbi.nlm.nih.gov/34748727
https://pubmed.ncbi.nlm.nih.gov/34748727
Publikováno v:
Arthritis Research & Therapy
Arthritis research & therapy, 15(4):R93. BioMed Central Ltd.
Arthritis research & therapy, 15(4):R93. BioMed Central Ltd.
Introduction In this study, we tested the ability of small molecule inhibitors of WNT/β-catenin signaling to block interleukin 1β (IL-1β)- and tumor necrosis factor α (TNFα)-induced cartilage degradation. Proinflammatory cytokines such as IL-1β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a142686fa0dc77b18665dde2f936efe
https://pubmed.ncbi.nlm.nih.gov/23965253
https://pubmed.ncbi.nlm.nih.gov/23965253
Akademický článek
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Autor:
Sirp A; Department of Chemistry and Biotechnology, Tallinn University of Technology, Tallinn, Estonia., Roots K; Department of Chemistry and Biotechnology, Tallinn University of Technology, Tallinn, Estonia., Nurm K; Department of Chemistry and Biotechnology, Tallinn University of Technology, Tallinn, Estonia., Tuvikene J; Department of Chemistry and Biotechnology, Tallinn University of Technology, Tallinn, Estonia; Protobios LLC, Tallinn, Estonia., Sepp M; Department of Chemistry and Biotechnology, Tallinn University of Technology, Tallinn, Estonia. Electronic address: m.sepp@zmbh.uni-heidelberg.de., Timmusk T; Department of Chemistry and Biotechnology, Tallinn University of Technology, Tallinn, Estonia; Protobios LLC, Tallinn, Estonia. Electronic address: tonis.timmusk@taltech.ee.
Publikováno v:
The Journal of biological chemistry [J Biol Chem] 2021 Dec; Vol. 297 (6), pp. 101381. Date of Electronic Publication: 2021 Nov 06.