Zobrazeno 1 - 10
of 61
pro vyhledávání: '"transcription factor SOX2"'
Publikováno v:
Zhongguo aizheng zazhi, Vol 33, Iss 1, Pp 36-44 (2023)
Background and purpose: The pathogenesis of lung cancer is diverse, however once confirmed, the best time for treatment is often missed. In this paper, the correlation between tumor suppressor gene (p53), protein gene product (PGP9.5), transcription
Externí odkaz:
https://doaj.org/article/8ee077e03fbe44bd91ad8e0862cd5395
Akademický článek
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Akademický článek
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Autor:
Köber, Ute, Koeber, Ute
Glioblastoma (GBM) is the most common adult brain cancer and one of the most lethal human cancers. SOX2-expressing GBM cells drive tumour growth and have a neural stem cell-like identity. Here, we developed novel synthetic superenhancers that inform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______463::6a37512a91f19d8cac173357eddafebc
https://hdl.handle.net/1842/38078
https://hdl.handle.net/1842/38078
Akademický článek
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Background: Small Cell Lung Cancer (SCLC) is a highly aggressive malignancy. MYC family oncogenes are amplified and overexpressed in 20% of SCLCs, showing that MYC oncogenes and MYC regulated genes are strong candidates as therapeutic targets for SCL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20079bd974296d67b84c4cb236f078ee
Publikováno v:
Epigenetics & Chromatin, Vol 10, Iss 1, Pp 1-18 (2017)
Kamstra, J H, Bastos Sales, L, Aleström, P & Legler, J 2017, ' Differential DNA methylation at conserved non-genic elements and evidence for transgenerational inheritance following developmental exposure to mono(2-ethylhexyl) phthalate and 5-azacytidine in zebrafish ', Epigenetics and Chromatin, vol. 10, no. 1, 20 . https://doi.org/10.1186/s13072-017-0126-4
Epigenetics and Chromatin, 10(1):20. BioMed Central
Epigenetics & Chromatin
Kamstra, J H, Bastos Sales, L, Aleström, P & Legler, J 2017, ' Differential DNA methylation at conserved non-genic elements and evidence for transgenerational inheritance following developmental exposure to mono(2-ethylhexyl) phthalate and 5-azacytidine in zebrafish ', Epigenetics and Chromatin, vol. 10, no. 1, 20 . https://doi.org/10.1186/s13072-017-0126-4
Epigenetics and Chromatin, 10(1):20. BioMed Central
Epigenetics & Chromatin
Background Exposure to environmental stressors during development may lead to latent and transgenerational adverse health effects. To understand the role of DNA methylation in these effects, we used zebrafish as a vertebrate model to investigate heri
Publikováno v:
Lung Cancer. 98:122-129
Objectives: The epithelial-to-mesenchymal transition (EMT) is considered as a key step in invasion of cancer cells. There are several regulator proteins responsible for induction of EMT, but underlying mechanisms are still unclear. SATB2 is an epigen
Autor:
James Briscoe, Mario Rosario Guarracino, Erin Stout, Mina Gouti, Paul R. Heath, Peter W. Andrews, Stuart L. Johnson, Valerie Wilson, Matthew Wind, Katrin Neumann, Anestis Tsakiridis, Marysia Placzek, Dylan Stavish, Thomas J. R. Frith, Oliver Thompson, Konstantinos Anastassiadis, Daniel Ortmann, James O.S. Hackland, Ilaria Granata
Publikováno v:
eLife, Vol 7 (2018)
eLife
Frith, T J, Granata, I, Wind, M, Stout, E, Thompson, O, Neumann, K, Stavish, D, Heath, P R, Ortmann, D, Hackland, J O, Anastassiadis, K, Gouti, M, Briscoe, J, Wilson, V, Johnson, S L, Placzek, M, Guarracino, M R, Andrews, P W & Tsakiridis, A 2018, ' Human axial progenitors generate trunk neural crest cells in vitro ', eLIFE, vol. 7 . https://doi.org/10.7554/eLife.35786
eLife 7 (2018). doi:10.7554/eLife.35786
info:cnr-pdr/source/autori:Frith T.J.R.; Granata I.; Wind M.; Stout E.; Thompson O.; Neumann K.; Stavish D.; Heath P.R.; Ortmann D.; Hackland J.O.S.; Anastassiadis K.; Gouti M.; Briscoe J.; Wilson V.; Johnson S.L.; Placzek M.; Guarracino M.R.; Andrews P.W.; Tsakiridis A./titolo:Human axial progenitors generate trunk neural crest cells in vitro/doi:10.7554%2FeLife.35786/rivista:eLife/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume:7
eLife
Frith, T J, Granata, I, Wind, M, Stout, E, Thompson, O, Neumann, K, Stavish, D, Heath, P R, Ortmann, D, Hackland, J O, Anastassiadis, K, Gouti, M, Briscoe, J, Wilson, V, Johnson, S L, Placzek, M, Guarracino, M R, Andrews, P W & Tsakiridis, A 2018, ' Human axial progenitors generate trunk neural crest cells in vitro ', eLIFE, vol. 7 . https://doi.org/10.7554/eLife.35786
eLife 7 (2018). doi:10.7554/eLife.35786
info:cnr-pdr/source/autori:Frith T.J.R.; Granata I.; Wind M.; Stout E.; Thompson O.; Neumann K.; Stavish D.; Heath P.R.; Ortmann D.; Hackland J.O.S.; Anastassiadis K.; Gouti M.; Briscoe J.; Wilson V.; Johnson S.L.; Placzek M.; Guarracino M.R.; Andrews P.W.; Tsakiridis A./titolo:Human axial progenitors generate trunk neural crest cells in vitro/doi:10.7554%2FeLife.35786/rivista:eLife/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume:7
The neural crest (NC) is a multipotent embryonic cell population that generates distinct cell types in an axial position-dependent manner. The production of NC cells from human pluripotent stem cells (hPSCs) is a valuable approach to study human NC b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::757175bb64b4ca0f3f2c03859803fcac
Publikováno v:
Epigenetics and Chromatin. 10(1)
Background: Exposure to environmental stressors during development may lead to latent and transgenerational adverse health effects. To understand the role of DNA methylation in these effects, we used zebrafish as a vertebrate model to investigate her