Zobrazeno 1 - 10
of 1 986
pro vyhledávání: '"transcription activator-like effector nuclease"'
Publikováno v:
The Journal of Reproduction and Development, Vol 67, Iss 3, Pp 177-187 (2021)
Genetically modified animals, especially rodents, are widely used in biomedical research. However, non-rodent models are required for efficient translational medicine and preclinical studies. Owing to the similarity in the physiological traits of pig
Externí odkaz:
https://doaj.org/article/0ad8c633862e49638b333be4fbb71d9c
Autor:
Satoshi Homma, Akihisa Murata, Masato Ikegami, Masakazu Kobayashi, Maki Yamazaki, Kento Ikeda, Takaaki Daimon, Hideharu Numata, Akira Mizoguchi, Kunihiro Shiomi
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The bivoltine strain of the domestic silkworm, Bombyx mori, exhibits a facultative diapause phenotype that is determined by maternal environmental conditions during embryonic and larval development. Although a recent study implicated a circadian cloc
Externí odkaz:
https://doaj.org/article/154d2109f38340b1926792aff31ad89f
Publikováno v:
Asian-Australasian Journal of Animal Sciences, Vol 33, Iss 2, Pp 360-372 (2020)
Objective Specific genomic sites can be recognized and permanently modified by genome editing. The discovery of endonucleases has advanced genome editing in pigs, attenuating xenograft rejection and cross-species disease transmission. However, off-ta
Externí odkaz:
https://doaj.org/article/3636cf9c5c5b42829201df8a59d7874d
Publikováno v:
Frontiers in Genetics, Vol 12 (2022)
The domesticated silkworm, Bombyx mori, is an economically important insect that synthesizes large amounts of silk proteins in its silk gland to make cocoons. In recent years, germline transformation strategies advanced the bioengineering of the silk
Externí odkaz:
https://doaj.org/article/6d6a2daf4a3c4e9c893dca927c946123
Publikováno v:
Plants, Vol 11, Iss 21, p 2860 (2022)
At least two sets of RNA polymerase (RNAP), nucleus (NEP)- and plastid (PEP)-encoded polymerases, recognizing distinct promoters exist in the plastids of land plants. Most plastid genes are regulated by multiple promoters with different strengths in
Externí odkaz:
https://doaj.org/article/738cf3af7d7648ec931c235e568f37cd
Autor:
Shakil Ahmad Bhat, Abrar Ahad Malik, Syed Mudasir Ahmad, Riaz Ahmad Shah, Nazir Ahmad Ganai, Syed Shanaz Shafi, Nadeem Shabir
Publikováno v:
Veterinary World, Vol 10, Iss 11, Pp 1361-1366 (2017)
Since centuries, the traits for production and disease resistance are being targeted while improving the genetic merit of domestic animals, using conventional breeding programs such as inbreeding, outbreeding, or introduction of marker-assisted selec
Externí odkaz:
https://doaj.org/article/4e6c3654175e4109ac70a47b2d211784
Publikováno v:
Current Stem Cell Research & Therapy. 17:267-279
Precise and site-specific genome editing through application of emerging and modern gene engineering techniques, namely zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and clustered regularly interspaced short
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66b56ba4fbbe107f7629698bda9fb3fc
https://doi.org/10.2174/1574888x16666211124095527
https://doi.org/10.2174/1574888x16666211124095527
Autor:
Chong FENG, Xi-rui LI, Hui-ting CUI, Chuan LONG, Xia LIU, Xing-hua TIAN, Deng-ke PAN, Yu-zhu LUO
Publikováno v:
Journal of Integrative Agriculture, Vol 15, Iss 7, Pp 1540-1549 (2016)
The transcription activator-like effector nuclease (TALEN) technique combined with the somatic cell nuclear transfer (SCNT) method has been successfully applied for creating genetically modified pigs. However, methods for isolating cells with biallel
Externí odkaz:
https://doaj.org/article/893ea718894a455cb3d0939519760289
Publikováno v:
Asian-Australasian Journal of Animal Sciences, Vol 29, Iss 4, Pp 564-570 (2016)
The Sal-like 1 gene (Sall1) is essential for kidney development, and mutations in this gene result in abnormalities in the kidneys. Mice lacking Sall1 show agenesis or severe dysgenesis of the kidneys. In a recent study, blastocyst complementation wa
Externí odkaz:
https://doaj.org/article/ce5ebd6ad16a411ba798171f986f1b25
Autor:
Laurent Poirot, Alexandre Juillerat, Diane Tkach, Ming Yang, Philippe Duchateau, Selena Kazancioglu, Aymeric Duclert, Alex Boyne
Publikováno v:
FEBS Open Bio, Vol 12, Iss 1, Pp 38-50 (2022)
FEBS Open Bio
FEBS Open Bio
Gene editing enables scientists to make precise changes to the genome of an organism using the cell’s own ability to repair damaged DNA using a supplied DNA template. In recent years, gene editing has been applied clinically in the treatment of dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19d48658e4280aca4614dcbe916de048
https://doaj.org/article/b489919778d241b5b206cd7cf268dbe0
https://doaj.org/article/b489919778d241b5b206cd7cf268dbe0