Epoxide Hydrolysis as a Model System for Understanding Flux Through a Branched Reaction Scheme

Autor: Janfalk Carlsson, Åsa, Bauer, Paul, Dobritzsch, Doreen, Kamerlin, Shina C. L., Widersten, Mikael

Publikováno v: IUCrJ, Vol 5, Iss 3, Pp 269-282 (2018)
IUCrJ

Kinetic rates and computer simulations can explain regioselectivity and stereoconfiguration in the products of enzyme-catalyzed epoxide hydrolysis.
The epoxide hydrolase StEH1 catalyzes the hydrolysis of trans-methylstyrene oxide to 1-phenyl­pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7143c018a24a63606987b51307e45361
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-343750

Epoxide hydrolysis as a model system for understanding flux through a branched reaction scheme.

Autor: Janfalk Carlsson Å; Department of Chemistry, BMC, Uppsala University, Box 576, 751 23 Uppsala, Sweden., Bauer P; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, BMC Box 596, 751 24 Uppsala, Sweden., Dobritzsch D; Department of Chemistry, BMC, Uppsala University, Box 576, 751 23 Uppsala, Sweden., Kamerlin SCL; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, BMC Box 596, 751 24 Uppsala, Sweden., Widersten M; Department of Chemistry, BMC, Uppsala University, Box 576, 751 23 Uppsala, Sweden.

Publikováno v: IUCrJ [IUCrJ] 2018 Mar 22; Vol. 5 (Pt 3), pp. 269-282. Date of Electronic Publication: 2018 Mar 22 (Print Publication: 2018).