Zobrazeno 1 - 10
of 192
pro vyhledávání: '"trained innate immunity"'
Autor:
Tsvetelina Velikova, Issa El Kaouri, Konstantina Bakopoulou, Milena Gulinac, Kremena Naydenova, Martin Dimitrov, Milena Peruhova, Snezhina Lazova
Publikováno v:
Gastroenterology Insights, Vol 15, Iss 3, Pp 661-675 (2024)
Mucosal immunity and trained innate immunity of the gut play a pivotal role in maintaining intestinal homeostasis and defending against microbial pathogens. This review provides an overview of the mechanisms underlying mucosal immunity and the concep
Externí odkaz:
https://doaj.org/article/7208d8e1cba549c89d45eba25bd84b7f
Autor:
Mehdi Bamorovat, Iraj Sharifi, Mehdi Shafiei Bafti, Setareh Agha Kuchak Afshari, Mohammad Reza Aflatoonian, Ali Karamoozian, Abdollah Jafarzadeh, Raheleh Amirzadeh, Ahmad Khosravi, Zahra Babaei, Farzane Safa, Fatemeh Sharifi, Amireh Heshmatkhah
Publikováno v:
Journal of Epidemiology and Global Health, Vol 14, Iss 1, Pp 142-153 (2024)
Abstract Introduction Emerging infectious diseases such as SARS-CoV-2 can cause pandemics and create a critical risk for humans. In a previous pilot study, we reported that the immunological responses induced by cutaneous leishmaniasis (CL) could dec
Externí odkaz:
https://doaj.org/article/0072c3ef180f474e9dafda66376fc0b5
Autor:
Alisha Kang, Gluke Ye, Ramandeep Singh, Sam Afkhami, Jegarubee Bavananthasivam, Xiangqian Luo, Maryam Vaseghi‐Shanjani, Fatemah Aleithan, Anna Zganiacz, Mangalakumari Jeyanathan, Zhou Xing
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 7, Pp 1-14 (2023)
Abstract Bacillus Calmette‐Guérin (BCG) still remains the only licensed vaccine for TB and has been shown to provide nonspecific protection against unrelated pathogens. This has been attributed to the ability of BCG to modulate the innate immune s
Externí odkaz:
https://doaj.org/article/5c2bf5230b074316873aab5bc4197134
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Polymicrobial intra-abdominal infections (IAI) can lead to life-threatening sepsis with significant morbidity and mortality, especially when pathogenic fungi are involved. We have employed an established clinically relevant mouse model of fu
Externí odkaz:
https://doaj.org/article/578699ebd6e44690bb0e88d032773236
Autor:
Shiwei Hu, Danhong Xiang, Xinlu Zhang, Lan Zhang, Shengjie Wang, Keyi Jin, Liangshun You, Jian Huang
Publikováno v:
Virology Journal, Vol 19, Iss 1, Pp 1-14 (2022)
Abstract In recent years, the traditional cognition of immunological memory being specific to adaptive immunity has been challenged. Innate immunity can mount enhanced responsiveness upon secondary stimulation, and a phenomenon is termed trained inna
Externí odkaz:
https://doaj.org/article/1de664e8e050495180c7b2d28df4ae64
Publikováno v:
Clinical Immunology Communications, Vol 2, Iss , Pp 118-129 (2022)
Emerging research shows that innate immunity can also keep the memory of prior experiences, challenging the long-held notion that immunological memory is only the domain of the adaptive immune cells. However, the absence of immunological memory in in
Externí odkaz:
https://doaj.org/article/d0163d0ed570494680c9f9181a51d280
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
IntroductionWeight loss improves obesity-associated diabetes risk. However, most individuals regain weight, which worsens the risk of developing diabetes and cardiovascular disease. We previously reported that male mice retain obesity-associated immu
Externí odkaz:
https://doaj.org/article/b7ea8c13b6aa472f8c7d8ae7d5a30364
Autor:
Vipin M. Vashishtha
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 17, Iss 1, Pp 88-91 (2021)
The world is experiencing a pandemic of Coronavirus Disease (COVID-19) caused by type-2 Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2). Vaccination is the only option to prevent future surges of the disease. Efforts for developing an effe
Externí odkaz:
https://doaj.org/article/b75c950fd1544315b21d33ee4241b5de
Autor:
Haruka Mizobuchi, Gen-Ichiro Soma
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 10, Pp 1928-1934 (2021)
Microglia, which are tissue-resident macrophages in the brain, play a central role in the brain innate immunity and contribute to the maintenance of brain homeostasis. Lipopolysaccharide is a component of the outer membrane of gram-negative bacteria,
Externí odkaz:
https://doaj.org/article/48cb9c73cef44252867d722e35ad78e7
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Fungal-bacterial intra-abdominal infections (IAI) can lead to sepsis with significant morbidity and mortality. We have established a murine model of Candida albicans (Ca) and Staphylococcus aureus (Sa) IAI that results in acute lethal sepsis. Prior i
Externí odkaz:
https://doaj.org/article/5f4fea64c6cf4a07a613e97e8f94448f