Protein Kinase CK2 Acts as a Molecular Brake to Control NADPH Oxidase 1 Activation and Colon Inflammation

Autor: Liu, Dan, Marie, Jean-Claude, Pelletier, Anne-Laure, Song, Zhuoyao, Ben-Khemis, Marwa, Boudiaf, Kaouthar, Pintard, Coralie, Leger, Thibaut, Terrier, Samuel, Chevreux, Guillaume, El-Benna, Jamel, Dang, Pham My-Chan

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, 2022, 13 (4), pp.1073-1093. ⟨10.1016/j.jcmgh.2022.01.003⟩

International audience; BACKGROUND & AIMS: NADPH oxidase 1 (NOX1) has emerged as a prime regulator of intestinal mucosa immunity and homeostasis. Dysregulation of NOX1 may cause inflammatory bowel disease (IBD). It is not clear how NOX1 is regulated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0d262c7f56dca6454e597cf2438a8e
https://doi.org/10.1016/j.jcmgh.2022.01.003

Novel Insights on the Toxicity of Phycotoxins on the Gut through the Targeting of Enteric Glial Cells

Autor: Océane Reale, Antoine Huguet, Valérie Fessard

Publikováno v: Marine Drugs
Volume 17
Issue 7
Marine Drugs, Vol 17, Iss 7, p 429 (2019)
Marine drugs
Marine drugs, MDPI, 2019, 17 (7), pp.429. ⟨10.3390/md17070429⟩

In vitro and in vivo studies have shown that phycotoxins can impact intestinal epithelial cells and can cross the intestinal barrier to some extent. Therefore, phycotoxins can reach cells underlying the epithelium, such as enteric glial cells (EGCs),

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebe4f36602dc1989140a6b3f0c83e221

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